Pilot Study to Describe Immune Responses of Healthy Women Following Immunization With Varicella...
HealthyThe re-activating nature of Varicella Zoster Virus (VZV) may allow life long boosting when used as a vaccine vector in conjunction with HIV to generate durable immunity systemically and at the mucosa. This study aims to characterize mucosal immunity before and after vaccination with a commercial live-attenuated varicella-zoster virus vaccine with respect to immune activation state, mucosal homing properties and VZV-specific effector immune responses in healthy women at low risk for HIV acquisition.
ZOSTAVAX in Persons Imminently Receiving Chemotherapy for Solid Organ Tumors
ShinglesThis study evaluates if the shingles vaccine works in those persons that receive it before they receive chemotherapy for solid organ tumors. Half of the participants will receive the ZOSTAVAX shingle vaccine and half of the participants will not received anything.
Response and Clearance of Viral DNA Following Administration of Live Attenuated Varicella Vaccine....
VaricellaTransplantsVaricella zoster virus (VZV) can lead to significant morbidity and mortality in transplant recipients. Current recommendations suggest a 4 week waiting period between vaccination and transplantation and consideration of booster immunizations if antibody response does not reach target levels. This four week waiting period can result in delayed transplant, rejection of an optimal organ, or missed opportunity to vaccinate. However, these recommendations are not evidence based. This is a prospective study to look at the immune response to varicella vaccine in children with chronic liver disease. Investigators will evaluate: the time at which VZV DNA becomes undetectable in blood and saliva by PCR after vaccination in children with chronic liver disease and the difference in humoral and cell mediated immune response to varicella immunization between children with chronic liver disease and healthy children.
Reactivation of Varicella Zoster Virus and Risk of Vascular Disease
Varicella ZosterStroke2 moreThe purpose of this study is to investigate whether there is an association between stroke or heart attack and reactivation of varicella zoster virus, measured by antibody levels, using linked data from the Health Survey for England and secondary care.
Safety Study of Measles-Mumps-Rubella-Varicella (MMRV) Vaccine, Priorix-Tetra™ in Children Living...
MumpsRubella2 moreThis study will collect data on the safety of the MMRV vaccine (Priorix-Tetra™) used in routine practice in children aged 12 months to 12 years living in the Philippines.
Study to Estimate the Burden of Herpes Zoster (HZ) and Post-herpetic Neuralgia (PHN) in Italy
Herpes ZosterHerpes Zoster VaccineThe purpose of this study is to collect data on the incidence, complications, economic burden and impact on the quality of life in adults aged ≥ 50 years with HZ disease in Italy.
Seroprevalence Study of Hepatitis A, Varicella-Zoster, Cytomegalovirus, Herpes Simplex and Bordetella...
Viral Hepatitis VaccinesHepatitis A4 moreThe purpose of this study is to determine the seroprevalence of Hepatitis A Virus (HAV), Varicella-Zoster virus (VZV), Cytomegalovirus (CMV), Herpes Simplex (HSV) and Bordetella pertussis (BP)infections in Mexico.
Measuring Herpes Zoster and PHN Associated Burden of Illness and Health Care Utilization Costs in...
Herpes ZosterTotal 7 institutions will be recruited i.e. Clinical Infectious Disease Research Unit Department of Clinical Tropical Medicine, Faculty of Tropical Medicine Mahidol University,Bamrasnaradura Infectious Disease Institute ,Pramonkutklao Hospital,Rajavithi Hospital,NationalCancerInstitute,Institute of Dermatology,Raj Pracha Samasai Institute OBJECTIVES Measure the burden of illness due to herpes zoster (Zoster) and post-herpetic neuralgia (PHN) (severity and duration); Assess the quality of life (QoL) and quality adjusted life years (QALY) lost due to Zoster and PHN; Describe health care resource utilization associated with Zoster and PHN; Describe the direct and indirect costs per case of Zoster and PHN
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata...
Alopecia AreataDepressive Episode34 moreThis study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and incidence of psychiatric co-morbidities in people with alopecia areata, (3) the prevalence and incidence of autoimmune and atopic conditions in people with alopecia areata, and (4) the incidence of common infections in people with alopecia areata.
An Immunity Persistence Study of Live Attenuated Varicella Vaccine
VaricellaThis an open phase Ⅳ clinical trial of live attenuated varicella vaccines manufactured by Sinovac (Dalian) Vaccine Technology Co., Ltd .The purpose of this study is to evaluate the immunity persistence of live attenuated varicella vaccine at 5 and 8 years after primary immunization with live attenuated varicella vaccine.