Active clinical trials for "Hoarding Disorder"

The purpose of this study is to investigate whether a well-established case management model called Critical Time Intervention (CTI) can help individuals with hoarding disorder who are concerned about the risk of eviction. Each individual with hoarding disorder will be assigned to work with a CTI Specialist for 9 months, who will provide referrals for mental health treatment, legal consultations, and registration for entitlements. All participants will be offered a facilitated group intervention called the Buried in Treasures Workshop. The CTI Specialist will also facilitate reconnecting the individual with supportive family/friends and will monitor and support the de-cluttering of the patient's home.

This is multiple baseline study including up to three participants with a primary diagnosis of hoarding disorder. All patients will receive unblinded repetitive transcranial magnetic stimulation study intervention.

The purpose of this study is to understand the neural mechanisms of decision making in hoarding disorder.

Available data suggest that compulsive hoarders have cognitive deficits, particularly with sustaining attention that might contribute their hoarding symptoms.

The objective of this prospective observational cohort study is to answer the following clinically important questions: In patients with a pre-operative history of ICBs, what is the likelihood of improvement or deterioration in ICBs post-operatively? What is the risk of developing post-operative de novo ICBs after Subthalamic Nucleus DBS (STN DBS)? Which factors are important in predicting changes in ICBs after STN DBS? What is the impact of ICBs on carer's quality of life QoL and burden?

The present study is a single-group open-label investigation of the potential efficacy of Vortioxetine for treatment of 30 adult volunteers with Hoarding Disorder (HD) (flexible-dose study, with a target dose range 5-25mg). The proposed study will be the first Vortioxetine study in HD, and conducted at the Anxiety Treatment and Research Clinic (ATRC) Canada's largest academic anxiety clinic, a regional referral center for individuals with HD. The study requires a Letter of No Objection from Health Canada and the study will be approved by Hamilton Integrated Research Ethics Board (HiREB).

"Hoarding "is a common behavior among Holocaust survivors and is related to the traumatic events they have experienced, and we assume that storage behavior and eating disorders are related to future generations of Holocaust survivors.