search

Active clinical trials for "Hyperlipidemias"

Results 41-50 of 695

Efficacy and Safety of SHR-1209 Combined With Lipid-lowering Agents in Patients With Hypercholesterolemia...

HypercholesterolemiaHyperlipidemia

To evaluate the efficacy, safety, pharmacokinetics and immunogenicity of SHR-1209 subcutaneous administration in patients with hypercholesterolemia and hyperlipidemia after lipid-lowering therapy

Active7 enrollment criteria

Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying...

DyslipidemiasHigh Cholesterol9 more

This study will be a placebo-controlled, double-blind, randomized, phase 3 study to Evaluate the Efficacy, Safety, and Tolerability of Obicetrapib in Participants with a History of Heterozygous Familial Hypercholesterolemia (HeFH).

Active9 enrollment criteria

Randomized Controlled Trial of Alert-Based Computerized Decision Support for Optimizing Low-Density...

HyperlipemiaMixed1 more

A 400-patient U.S.-based single-center Quality Improvement Initiative in the form of a randomized controlled trial focused on the feasibility of implementation of this electronic alert-based CDS (EPIC BPA) based on LDL-C values. The 400 patients will be comprised of 200 in the "Hospitalized Patient Cohort" and 200 in the "Outpatient Clinic Cohort." The allocation ratio will be 1:1 for an electronic alert-based CDS (EPIC BPA) notification versus no notification.

Active7 enrollment criteria

Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy

DiabetesLipodystrophy1 more

Background: - Partial lipodystrophy can cause high blood fat levels and resistance to insulin. This can lead to health problems including diabetes. Researchers have found that the drug metreleptin improves health in people with this disease. Objective: - To test the safety and effectiveness of metreleptin. Eligibility: People age 6 months and older with partial lipodystrophy who have received metreleptin through NIH studies and shown improvement AND cannot get metreleptin other ways. Design: Participants will come to NIH approximately every 6 months during year one, then every 1 2 years. Financial assistance may be available for travel within the U.S. At visits, participants will get a supply of metreleptin to take home for daily injections, or it can be shipped to them inside the U.S. They will have: plastic catheter placed in an arm vein. blood tests, urine collection, and physical exam. oral glucose tolerance test, drinking a sweet liquid. ultrasound of the heart, liver, uterus, and ovaries. A gel and a probe are placed on the skin and pictures are taken of the organs. echocardiogram, which takes pictures of the heart with sound waves. Resting Metabolic Rate taken. A plastic hood is worn over the head while the oxygen they breathe is measured. Participants will have up to 3 DEXA scan x-rays per year. Participants may have: annual bone x-rays. liver biopsies every few years. A needle will be inserted into the liver to obtain a small piece. Participants will sign a separate consent for this. Participants must be seen regularly by their local doctors and have blood tests at least every 3-6 months at home.

Active16 enrollment criteria

Behavior Change Intervention for Cardiovascular Risk Reduction Among People Experiencing Homelessness...

Heart DiseasesDiabetes Mellitus4 more

This single-arm trial of the Cardiovascular Risk Reduction Among People Experiencing Homelessness (CV-Homes) intervention alone (n=8) will test the perception and feasibility of anticipated study procedures.

Active10 enrollment criteria

Improving How Older Adults at Risk for Cardiovascular Outcomes Are Selected for Care Coordination...

Cardiovascular DiseasesMyocardial Infarction8 more

This pragmatic clinical trial embedded in an accountable care organization will determine the comparative effectiveness of two approaches for assigning care coordinators to older adults at risk for cardiovascular outcomes. The hypothesis is that assigning care coordinators to older adults based on perceived need will be more effective at preventing emergency department visits and hospitalizations compared to usual care.

Enrolling by invitation8 enrollment criteria

Effect of ANKASCIN 568-P Products Regulating Blood Lipid

Hyperlipidemias

This study is a randomized, double-blind, placebo-controlled, parallel-controlled trial (24 weeks in total), divided into three periods (screening, treatment, and discontinuation follow-up)

Not yet recruiting14 enrollment criteria

Ezetimibe-Rosuvastatin Evaluation Study

HypercholesterolemiaHyperlipidemias1 more

Evaluation of the efficacy of the stable ezetimibe-rosuvastatin combination in patients with primary hypercholesterolemia in achieving the target plasma LCL-C level.

Recruiting11 enrollment criteria

Study to Evaluate the Effect of Improving Systolic BP and LDL-C Compared to Conventional Treatments...

HyperlipidemiasHypertension

The purpose of this study is to evaluate the effectiveness of Olostar Tablet on blood pressure and lipid profiles, obtain safety-related information for subgroups that failed to participate in the clinical trials, and to evaluate variables that affect treatment effectiveness.

Recruiting6 enrollment criteria

Telehealth Integrated Care Model in Patients With Cardiometabolic Disease

Cardiometabolic DiseaseHyperlipidemia

The objective of this study is to evaluate the telehealth integrated care model for its clinical efficacy, medical resource utilization, health economics measurement, and satisfaction survey indicators in hyperlipidemia patients and other cardiometabolic diseases. The result of the study will provide evidence for the value of integrated model in the treatment of patients with cardiometabolic syndrome.

Recruiting8 enrollment criteria
1...456...70

Need Help? Contact our team!


We'll reach out to this number within 24 hrs