Postprandial Effects of Milk and Milk Constituents
HyperlipidemiaInflammationThe purpose of this study is to determine whether the addition of milk or the milk constituents calcium and protein to a high-fat breakfast affects the postprandial lipid and inflammatory response.
Pilot Study Testing Feasibility of Health Screening at Farm Site
Diabetes ScreeningHyperlipidemia Screening1 moreTest the feasibility of performing worksite screening of Hypertension, Diabetes and Hyperlipidemia for six months
Single Radiolabeled Dose Study to Investigate the Absorption, Metabolism and Excretion of [14C]-ETC-1002...
HyperlipidemiaThis Phase 1 study will assess the mass balance recover of carbon-14 (14C) labelled ETC-1002 and the routes and rates of excretion of [14C]-ETC-1002
Assessment of Non-Fasting vs. Fasting Lipid Measures in Diabetes Patients
Diabetes MellitusNormal Glucose Metabolism1 moreThis study will examine whether fasting and non-fasting lipid measures can provide similar clinical information in order to guide lipid management by primary physicians. It will compare fasting vs. non-fasting lipid measurements in patients with and without diabetes.
Effects of Soy Protein on Serum paraoxonase1 Activity and Lipoproteins in Postmenopausal Women
PostmenopausalHyperlipidemiaparaoxonase 1 is involved to prevent LDL and HDL oxidation,so increase of it's activity leads to lower risk of coronary heart disease.In postmenopausal women ,we have decrease of paraoxonase1 activity and soy proteins may increase paraoxonase1 activity
A Randomized Controlled Trial of a Novel Community-based Primary and Secondary Cardiovascular Prevention...
Vascular DiseaseDiabetes3 moreVIP is a demonstration project with a goal to decrease modifiable risk factors for those with a higher risk of having a vascular event such as a heart attack or stroke or of developing vascular disease. Introduced as a study, VIP compares whether there is a significant reduction of modifiable vascular risk factors among patients who are involved in a personalized directed program versus those being provided standard care by their physician. Health care providers work collaboratively with the 'VIP Team' to improve the participants' vascular health.
A Pilot Study on the Effect of Vitamin D Treatment in Patients With Statin-Associated Myalgia
HyperlipidemiaThe purpose of this study is to measure the effect vitamin D has in alleviating muscle pain or aches that may be caused by taking certain medications for treating high cholesterol.
Mechanisms and Interventions to Address Cardiovascular Risk of Gender-affirming Hormone Therapy...
HypertensionHyperlipidemiasGender-identity differences are becoming increasingly diagnosed in the US and treatment with gender-affirming hormone therapy (GAHT) is associated with improved mental health outcomes. However, GAHT has been associated with cardiovascular risk in adult transgender patients, although mechanisms and treatments have not been explored. Understanding the cardiovascular effects and exploring the potential of a lipid sensitive statin as a potential treatment is important to optimizing safe treatment strategies for transgender men in mitigating this modifiable risk factor, and designing and implementing effective interventions.
Study on the Efficacy and Safety of Oral Probucol Tablets in Patients With Hyperlipidemia - Post-Marketing...
HyperlipidemiaThe primary objective of this post marketing surveillance (PMS) is to determine the safety and efficacy of probucol in lowering the level of serum cholesterol in the blood.
Effects of Use of a Connected Pillbox On Medication Adherence
Diabetes MellitusHypertension1 moreMedication adherence is defined as the extent to which a patient takes his or her medication as prescribed by their healthcare provider. One third to one half of all patients in the United States do not take their medication as directed, resulting in nearly $100B in avoidable hospital costs per year. Recent efforts to improve medication adherence in patients with multiple comorbidities have turned to case management and disease management programs. Connected monitoring devices offer an alternative- or supplement- to frequent nurse visits and outreach. These devices enable frequent monitoring and intervention but can also generate large volumes of data that can be difficult for care teams to manage. The present study explores the use of one such device- a technology-enabled, connected pillbox. Given the continued emphasis on bending the cost curve in US healthcare, clinical validation of tools that may improve the management of costly chronic diseases, such as diabetes, is essential.