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Active clinical trials for "Hyperlipoproteinemias"

Results 161-170 of 298

A Pilot Study to Evaluate the Lipid Effects of TRIA-662

HypertriglyceridemiaMixed Hyperlipidemia

The purpose of this pilot study is to learn what study factors are important in designing a large, full-scale study of the effects of TRIA-662 on serum triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) levels. In this study, patients will first enter a Single-blind, dietary-controlled baseline period and receive 1000 mg placebo or active drug three times daily with meals (i.e., breakfast, lunch, and dinner) for 6 - 8 weeks. If the qualify to continue, they will then receive up to 2000 mg of active or placebo drug for an additional 14 weeks. Active drug will be given to 48 patients and placebo drug will be given to 16 patients. However, neither the patients not the clinic staff will know which patients are on active or placebo drug until the end of the study.

Completed53 enrollment criteria

Pilot Study To Assess CAT-2003 in Patients With Chylomicronemia

Lipoprotein Lipase DeficiencyFamilial4 more

The purpose of this study is to assess safety and efficacy of CAT-2003 in patients with chylomicronemia. The study will evaluate the effects of CAT-2003 on fasting total and chylomicron triglyceride levels, as well as postprandial total and chylomicron triglyceride clearance. This is a single-blind study. All patients will receive placebo for 1 week, and CAT-2003 for 12 weeks during the 13 week treatment period.

Completed7 enrollment criteria

Trial of Antroquinonol in Patients With Hypercholesterolemia and Hyperlipidemia

Hyperlipidemias

Identified the efficacy of Antroquinonol (Hocena 50mg) in triglyceride, lipid-lowering and fatty liver.

Completed22 enrollment criteria

Evaluation of the Fixed-dose Combination of Irbesartan/Atorvastatin in Type 2 Diabetic Patients...

Type 2 Diabetes Mellitus

Primary Objective: To evaluate the effect of irbesartan/atorvastatin fixed-dose combination comparing to each irbesartan and atorvastatin on flow mediated dilation change in type 2 diabetic patients diagnosed with hyperlipidemia, hypertension. Secondary Objective: To evaluate efficacy of blood pressure and hyperlipidemic factors of irbesartan/atorvastatin fixed-dose combination in type 2 diabetic patients diagnosed with hyperlipidemia and hypertension, with adequately controlled blood glucose levels in groups.

Completed39 enrollment criteria

The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants...

Familial Chylomicronemia SyndromeLipoprotein Lipase Deficiency1 more

An open-label study of volanesorsen (ISIS 304801) administered subcutaneously to participants with FCS.

Completed19 enrollment criteria

Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia

DyslipidemiaHypercholesterolemia1 more

The purpose of this study is to determine the safety and efficacy of different doses of CAT-2003 in patients with hyperlipidemia when CAT-2003 is taken for 4 weeks. The study will evaluate effects of CAT-2003 on (1) fasting triglycerides and non-HDL-C in patients with moderate hypertriglyceridemia and (2) fasting LDL-C levels in combination with a statin in patients with hypercholesterolemia who are on a statin.

Completed10 enrollment criteria

Efficacy and Safety of Imported Probucol to Treat Hyperlipidemia

Hyperlipidemia

The purpose of this study is to evaluate the efficacy and safety of imported Probucol in hyperlipidemia patients.

Completed18 enrollment criteria

Combined Effects of Bioactive Compounds in Lipid Profile

HyperlipidemiaLow-density-lipoprotein-type1 more

The aim of this study is to demonstrate whether, along with dietary recommendations, Armolipid Plus ® can improve the profile of patients with elevated plasma LDL-C acting as a change of lifestyle therapy (TLC) according to the definition of Adult Treatment Panel III (ATP III)

Completed10 enrollment criteria

Efficacy and Safety of HL-040XC in Essential Hypertension and Hyperlipidemia

Essential HypertensionHyperlipidemia

The purpose of this study is to evaluate efficacy and safety of HL-040XC in patients with essential hypertension and hyperlipidemia

Completed5 enrollment criteria

Telephone Based Management of Hyperlipidemia

Hyperlipidemia

The purpose of the study is to demonstrate that systematic self measurement of blood lipids reduces LDL cholesterol more effectively than standard care. The hypothesis is that cholesterol lowering medication adherence will be improved with self monitoring and reporting of frequent blood lipids and the percentage of patients achieving LDL goal will be greater than without home monitoring.

Completed4 enrollment criteria
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