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Active clinical trials for "Hyperplasia"

Results 1-10 of 926

Effect of Electroacupuncture on Benign Prostatic Hyperplasia

Benign Prostatic Hyperplasia

The study aims to assess the efficacy and safety of electroacupuncture among men with benign prostatic hyperplasia (BPH), compared with sham electroacupuncture.

Recruiting14 enrollment criteria

Study of Lu AG13909 in Participants With Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia

This study will evaluate the effects of different doses of Lu AG13909 in adult participants with congenital adrenal hyperplasia, also called CAH. CAH is a rare genetic disorder that affects a person's ability to produce certain hormones. The main goals of this study are to learn about the safety and tolerability of Lu AG13909, how Lu AG13909 behaves in the body, and how the body responds to Lu AG13909.

Recruiting10 enrollment criteria

Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital...

Congenital Adrenal HyperplasiaClassic Congenital Adrenal Hyperplasia

The purpose of this Phase 2, open-label, sequential dose cohort study is to evaluate the safety, efficacy, and pharmacokinetics (PK) of CRN04894 in participants with classic congenital adrenal hyperplasia (CAH) caused by 21-hydroxylase deficiency.

Recruiting21 enrollment criteria

Levonorgestrel-Releasing Intrauterine System With or Without Everolimus in Treating Patients With...

Atypical Endometrial HyperplasiaFIGO Grade 1 Endometrial Endometrioid Adenocarcinoma1 more

This randomized phase II trial studies how well levonorgestrel-releasing intrauterine system works when given alone or with everolimus in treating patients with atypical hyperplasia (a pre-cancerous growth of the lining of the uterus) or stage IA grade 1 endometrial cancer. The levonorgestrel-releasing intrauterine system is designed to prevent pregnancy by releasing a hormone called levonorgestrel, which is a type of progesterone. Progesterone is a common type of hormone that is used to prevent pregnancy and may prevent or slow tumor cell growth. Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether the levonorgestrel-releasing intrauterine system works better with or without everolimus in treating patients with atypical hyperplasia or stage IA grade 1 endometrial cancer.

Recruiting35 enrollment criteria

Fertility Sparing Management of EndomeTrial Cancer and Hyperplasia

Endometrial HyperplasiaEndometrial Cancer1 more

This study protocol evaluates the use of hysteroscopic endomyometrial resection in women diagnosed with atypical endometrial hyperplasia or grade I endometrial cancer who have not responded to anti-hormone therapy. Patients in this study wish to preserve fertility.

Recruiting27 enrollment criteria

ProVee Urethral Expander System IDE Study (ProVIDE)

Benign Prostatic Hyperplasia With Symptomatic Lower Urinary Tract Symptoms

A study to evaluate the safety, performance, and effectiveness of the ProVee Urethral Expander System (Investigational Device) when used in subjects with symptomatic urinary obstruction related to benign prostatic hyperplasia (BPH).

Recruiting46 enrollment criteria

Loxenatide Plus LNG-IUS in Endometrial Atypical Hyperplasia

Atypical Endometrial HyperplasiaObesity1 more

To study if polyethylene glycol loxenatide plus levonorgestrel-releasing intrauterine system (LNG-IUS) will improve response rates in patients with endometrial atypical hyperplasia.

Recruiting19 enrollment criteria

Early Identification and Treatment of Developmental Trochlear Femoral Dysplasia

TROCLEAR DYSPLASIA

Title Early identification and treatment of developmental trochlear femoral dysplasia. Objectives To identify developmental trochlear femoral dysplasia (DTFD) in the newborn early after birth by ultrasound and evaluate the effect of its treatment with a modificed Pavlik harness. Study design Randomized triple-blind clinical trial. Study population Newborns with risk factors for the development of DTFD. Treatment of subjects Treatment using a modified Pavlik harness currently used for the treatment of developmental dysplasia of the hip (CDD) over a period of two months. Variables analyzed Trochlear groove angles measured by ultrasound before and after the intervention in the treatment group and control group. Follow-up Two weeks, eight weeks and six months. Statistic analysis Student's t test will be used for related samples to compare and analyze the results of each group at the beginning and after the treatment (intervention group) or follow-up (control group). Study will be triple blinded.

Recruiting5 enrollment criteria

REZŪM vs. Dual Drug Therapy for Symptomatic Benign Prostatic Hyperplasia in Sexually Active Men...

Benign Prostatic Hyperplasia (BPH)

The study objective is to compare water vapor thermotherapy with the REZŪM™ System to dual drug therapy for the treatment of symptomatic benign prostatic hyperplasia refractory to alpha-blocker monotherapy in sexually active men.

Recruiting18 enrollment criteria

A Ph2b to Evaluate Tildacerfont in the Reduction of Glucocorticoid Steroid Doses in Adult CAH

Congenital Adrenal Hyperplasia

An investigation of the ability of Tildacerfont to reduce supraphysiologic glucocorticoid dosing in classic CAH subjects up to 76 weeks of treatment. Optional open label extension up to 240 weeks.

Recruiting8 enrollment criteria
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