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Active clinical trials for "Essential Hypertension"

Results 11-20 of 432

Clinical Trial to Evaluate the Efficacy and Safety of D064 and D702 Combination Therapy

Essential Hypertension

Clinical Trial to Evaluate the Efficacy and Safety of D064 and D702 Combination Therapy

Recruiting9 enrollment criteria

A Study to Evaluate the Efficacy and Safety of BR1017A and BR1017B Combination Therapy in Essential...

Essential HypertensionPrimary Hypercholesterolemia

The objective of this clinical study is to evaluate the efficacy and safety by comparing BR1017A+BR1017B treatment group to BR1017A treatment group and BR1017B treatment group respectively at Week 8 in essential hypertension patients with primary hypercholesterolemia

Recruiting20 enrollment criteria

LCZ696 in Advanced LV Hypertrophy and HFpEF

Heart FailureEssential Hypertension

Patients with advanced LVH and HFpEF will be randomly assigned in open-label fashion to receive LCZ696 titrated to 200 mg twice daily or valsartan titrated to 160 mg twice daily, and will be treated for 24 weeks.

Recruiting23 enrollment criteria

A Study to Evaluate the Efficacy and Safety of HCP2102 in Essential Hypertension Patients

Hypertension

A multicenter, randomized, double-blind, phase III study to evaluate the efficacy and safety of HCP2102 in patients with essential hypertension

Recruiting24 enrollment criteria

Blood Pressure Reduction in Patients With Asymptomatic Aortic VALVE Stenosis

Aortic Valve StenosisHypertension,Essential1 more

The aim of this study is to investigate the effect of strict blood pressure control versus conventional care in patients with asymptomatic moderate to severe aortic valve stenosis. The study is a randomized (1:1), open label, controlled intervention trial. Hypothesis: Strict BP control for 12 months reduces the progression of LV remodelling compared to conventional treatment. Strict BP control for 2 years reduces the increase in aortic valve calcification and LV remodelling compared to conventional treatment. Strict BP reduction for up to 10 years reduces the need for aortic valve replacement and cardiovascular events compared to conventional care.

Recruiting16 enrollment criteria

Ultrasound Ablation for Essential Hypertension(FIM)

Uncontrolled Essential Hypertension

To evaluate the safety and feasibility of disposable intravascular ultrasound ablation catheter and ultrasound ablation instrument in the treatment of essential hypertension.

Recruiting17 enrollment criteria

Focused Power Ultrasound Mediated Inferior Perirenal Adipose Tissue Modification Therapy for Essential...

HypertensionBlood Pressure1 more

This randomized, double blinded, sham-control trial aims to evaluate the efficacy and safety of a novel focused power ultrasound mediated inferior perirenal adipose tissue modification therapy for essential hypertension.

Recruiting20 enrollment criteria

Effect of Gut Microbiome Restoration on Primary Hypertension Via Dietary Intervention

Hypertension

Mounting preclinical and clinical evidences have proved the optimal role of diets (i.e. DASH (Dietary Approaches to Stop Hypertension) diet, Mediterranean diet) on BP control and a causal role of gut microbiota on the pathogenesis of primary hypertension. Dietary changes appeared to reshape gut microbiota and to ameliorate diseases such as Type 2 Diabetes. A hypothesis is thus raised that dietary changes can be a potential approach to ameliorate hypertension via gut microbiome restoration. This pilot study will utilize an innovative natural dietary formulation (patent ID: CN110250417A), in comparison with classic antihypertensive treatment (losartan 50mg per day) and usual care (guideline-based patient education and lifestyle recommendations), to investigate its effect and safety on primary hypertension treatment, and the underlying mechanisms of gut microbiome restoration.

Recruiting18 enrollment criteria

Study to Evaluate the Efficacy and Safety of SPH3127 In Patients With Mild-moderate Essential Hypertension...

Essential Hypertension

The primary aim of the study is to assess the antihypertensive efficacy of SPH3127 in patients with mild to moderate essential hypertension.

Recruiting14 enrollment criteria

Feasibility and Effectiveness of a Ring-type Blood Pressure Measurement Device

HypertensionBlood Pressure5 more

The goal of this clinical trial is to evaluate the feasibility and effectiveness of a ring-type blood pressure measurement device compared to a 24-hour ambulatory blood pressure monitoring device in patients with hypertension or suspected hypertension. The main question it aims to answer is whether the 24-hour blood pressure measurement accuracy of the ring-type blood pressure monitor is similar to that of the 24-hour ambulatory blood pressure monitor. To participate, subjects must wear a ring blood pressure monitor and an ambulatory blood pressure monitor simultaneously for 24 hours.

Recruiting10 enrollment criteria
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