Assessment of Gastric pH Changes Induced by Ascorbic Acid Tablets
HypochlorhydriaThis study evaluates the use of ascorbic acid, vitamin C, to temporary reduce gastric pH in individuals with omeprazole induced hypochlorhydia. All participants will receive ascorbic acid tablets to measure the change in gastric pH.
Study to Evaluate Effects of Food or Proton Pump Inhibitor on the Pharmacokinetics of Itraconazole...
AchlorhydriaThe aim of this study is to evaluate the effects of food or proton pump inhibitor on the pharmacokinetics of itraconazole in healthy volunteers.
Does Omeprazole Decrease Intestinal Calcium Absorption?
OsteoporosisAchlorhydria2 moreThe purpose of this study is to measure the effect of omeprazole on intestinal calcium absorption in postmenopausal women.
Clinical Experiment of Helicobacter Pylori Transmission
InfectionAchlorhydriaThe study proposes to test whether chronic infection with Helicobacter pylori protects individuals from symptomatic infection with enteropathogenic E. coli. The study will also evaluate the effect of gastric acidity in this relationship.
Cobalamin Absorption From Fortified Food
Vitamin B-12 DeficiencyAchlorhydriaTo determine B12 bioavailability from 14C-B12 fortified bread in healthy subjects and in subjects with proton pump inhibitor induced achlorhydria.
Evaluating Patients With Abnormal Levels of Gastric Acid
AchlorhydriaGastrinoma1 moreThis study is used by the Digestive Diseases Branch to evaluate patients with suspected abnormalities in the secretion of gastric acid. The level of gastric acid is measured by analyzing the gastric juices of each individual patient. The gastric acid sample is obtained by a procedure known as nasogastric suctioning, where a thin plastic tube is passed from the nose to the stomach. Depending on the patient's present condition further diagnostic testing may be required to achieve a diagnosis.