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Active clinical trials for "Hypoxia"

Results 981-990 of 998

Integrated Clinical-radiological Analysis of Hypoxia Markers in Pediatric Osteosarcomas

Osteosarcoma in Children

The aim of this pilot study is therefore to retrospectively measure the volume and percentage of necrosis on diagnostic MRI in T1 sequence and in parallel to study the expression of immunohistochemical markers of hypoxia (HIF-1α, CAIX , HIF-2α, pS6, phosphomTor, CD163 and CD68) on diagnostic biopsies of high-grade osteosarcomas from 2007 to 2018 in the Strasbourg center, focusing on the pediatric population. The investigators will systematically carry out a correlation analysis between these different parameters and with the clinical data of these same patients (response to chemotherapy, presence of metastases or not and overall and recurrence-free survival). This will eventually make it possible to highlight new prognostic markers at diagnosis.

Unknown status10 enrollment criteria

Hypoxia Blood Validation in Multiple Pulse Oximeters

Hypoxia

The purpose of this study is to evaluate the SpO2 accuracy and performance of multiple pulse oximeters during non-motion conditions over the range of 70-100% SaO2 as compared to arterial blood samples assessed by CO-Oximetry for SpO2 validation. This study is observational in nature which quantifies device performance and accuracy in comparison to a Reference Standard.

Unknown status2 enrollment criteria

The Prediction Model of Hypoxemia for Safe Bronchoscopy

HypoxemiaObstructive Sleep Apnea

The purpose of this study is to develop the hypoxemia prediction model during fiberoptic bronchoscopy under MAC(monitored anesthesia care) anesthesia.

Unknown status6 enrollment criteria

Early Recognition of Hypoxia in Pediatric Patient Sedation

Desaturation of Blood

Early recognition of hypoxia through monitoring in sedation practices in pediatric patients

Unknown status5 enrollment criteria

New Biomarkers of Neurological Outcome After a Sudden Cardiac Death

Cardiac Sudden DeathHypoxia Brain2 more

The aim of the project is to establish the value of circulating microparticles as a new biomarker for neurological prognosis of patients recovered from sudden cardiac death who remain comatose.

Unknown status7 enrollment criteria

Neonatal Hypoxic Ischemic Encephalopathy:Early Diagnosis and Management of Comorbidities

Neonatal Hypoxic Ischemic Encephalopathy

Perinatal asphyxia is common cause of acquired neonatal brain injury in neonates associated with hypoxic-ischemic encephalopathy, leading to long-term neurologic complication or death. In 2000, the neonatal mortality rate in Egypt was found to be 25 per 1000 live birth. In this survey, hypoxic ischemic encephalopathy accounts for 18% of neonatal mortality and is the second most common cause of neonatal death.

Unknown status7 enrollment criteria

Role of NLRP3 Inflammasone and Hypoxia in the Severity of Osteoporosis in Patients With Bronchiectasis...

Bronchiectasis AdultOsteoporosis1 more

The objectives of this research grant are to determine the association of hypoxia with the severity of osteoporosis in the patients with bronchiectasis and whether the mechanism of inflammation is triggered by inflammasones, which makes it more prone to osteoporosis in patients with bronchiectasis.

Unknown status10 enrollment criteria

Assessment of the Efficacy of Tracheal Oxygen Administration During Bronchoscopy - a Phase II Trial...

Hypoxaemia

The aim of the present study is to measure the time to correction of O2 saturation when in case of desaturation below 90%, O2 administration is switched from the nasal to the tracheal route at a similar flow rate.

Unknown status3 enrollment criteria

Non-Contact Respiratory Rate Monitoring

Hypoxia

The purpose of this study is to compare thermographic estimates of respiratory rate to manual counting (visual inspection) and thoracic impedance-based methods. Thermographic methods rely on detection of temperature changes in the nose and mouth that occur as room temperature air passes through the nose and mouth during ventilation, and may offer a non-invasive means of measuring respiratory rate without requiring any patient contact.

Unknown status5 enrollment criteria

Assessment of Tidal Volume During Non Invasive Oxygenation Techniques

Respiratory Failure With Hypoxia

High Tidal volume is one of the main mechanisms that lead to lung injuries under mechanical ventilation (ventilator induced lung injury: VILI). It could also induce lung damage during spontaneous or assisted ventilation (patient-self inflicted lung injury: P-SILI). Different non invasive oxygenation devices are available to deliver oxygen during acute hypoxemic respiratory failure: high concentration mask, high flow nasal canula and non-invasive ventilation (with bucco-nasal mask or helmet). The investigators hypothesized that the device may influence the tidal volume. Therefore, the objective of this study is to measure and compare the tidal volume during the use of each device. Tidal volume will be measured using Electrical impedence tomography.

Unknown status12 enrollment criteria
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