Prucalopride for Postoperative Ileus in Patients Undergoing Gastrointestinal Surgery
Postoperative IleusThe purpose of this study is to evaluate the effect and safety of prucalopride on recovery of gastrointestinal function in patient undergoing major gastrointestinal surgery. The investigators hypothesize that patients who take prucalopride after major gastrointestinal surgery will have shorter duration of postoperative ileus.
Pilot Study: Anti-inflammatory Effect of Peroperative Stimulation of the Vagus Nerve
Postoperative IleusHypothesis: Electrical stimulation of the abdominal vagus nerve has an anti-inflammatory effect and represents a new therapeutic approach to shorten postoperative ileus. Aims: In the present pilot study, the investigators want to evaluate the anti-inflammatory effect of peroperative electrical stimulation of the vagus nerve. To this end, the following aims are formulated: to optimize the technique of intra-operative electrical vagus nerve stimulation to show that electrical stimulation of the intra-abdominal vagus nerve reduces the inflammatory response to abdominal surgery to evaluate whether electrical stimulation of the vagus nerve leads to clinical improvement (collect pilot data)
Study to Evaluate LB1148 for Return of Gastrointestinal Function, Decrease Post-Operative Ileus...
IleusThe purpose of this study is to establish preliminary evidence of the efficacy, safety, and tolerability of LB1148 for the treatment of return of gastrointestinal function and decrease Post-Operative Ileus in subjects undergoing elective bowel resection.
Interventions to Decrease the Impact of Post-OPerative Ileus After Liver Transplant or Resection...
IleusThis is a randomized controlled trial to assess ways to address post-operative ileus (POI) in adult patients on the liver transplant service undergoing either liver transplant or resection surgery. Patient who speak and understand English will be randomized into one of three groups including a.)control group receiving standard therapy for post-operative ileus, b.)group receiving standard therapy and acupressure bracelets, and c.)group receiving standard therapy and sugar free gum four times daily.
Does Coffee Consumption Prevent or Shorten Postoperative Ileus After Colon Resection?
Postoperative IleusThe purpose of this study is to determine if consuming an 8 ounce cup of coffee with breakfast and lunch is effective in preventing or reducing postoperative ileus.
Study of Intravenous (IV) Methylnaltrexone Bromide (MNTX) in the Treatment of Post-Operative Ileus...
Post-Operative Ileus (POI)To evaluate the safety and efficacy of MNTX in participants who have undergone segmental colectomy and to assess if the time between the end of surgery and the first bowel movement is significantly shorter in the MNTX regimen than the equivalent assessment using a placebo regimen.
Randomized Clinical Trial of Bisacodyl Versus Placebo on Postoperative Bowel Motility in Elective...
Postoperative IleusPostoperative bowel dysmotility is a frequent condition after colorectal surgery. The influence of colon stimulating laxatives have not been studied. This prospective, randomized, double blind, placebo controlled study assesses the influence of bisacodyl on postoperative bowel motility in patients undergoing elective colorectal surgery. The hypothesis of this trial was that bisacodyl has a beneficial effect on the duration of postoperative ileus.
Safety and Efficacy of IV Infusion of TZP-101 for POI After Major Open Abdominal Surgery
Postoperative IleusThe purpose of this study is to determine whether TZP-101 is effective in the management of post operative ileus in subjects undergoing major open abdominal surgery (i.e. partial large bowel resection).
The Impact of Sugammadex on Ileus After Abdominal Wall Reconstruction
HerniaVentral1 moreThe aim of the study is to determine if the usage of sugammadex would reduce the time to return of bowel function when compared to standard of care (neostigmine/glycopyrrolate) when used for neuromuscular blockade reversal in patients with open abdominal wall reconstruction (AWR).
Does Sugared or Sugar Free Chewing Gum Reduces Postoperative Ileus After Laparoscopic Cholecystectomy...
Postoperative Ileus.Laparoscopic cholecystectomy is now very common procedure to remove the gall bladder from abdomen. After this procedure many patients suffer from the non functioning of intestine and stomach which is very common after any abdominal surgery. Many efforts tried to reduce this non functioning period or postoperative ileus but non of them was superior later on. The investigators want to evaluate the role of chewing gum for reducing postoperative ileus. The investigators hypothesis is that Chewing gum after laparoscopic cholecystectomy reduces postoperative ileus and sugared preparations are more effective to reduce it.