Genetic Mapping for Cardiac Risk Assessment
Angina PectorisMyocardial Infarction3 moreThe main objective of the GENOCOR project (Genetic mapping for cardiac risk assessment) is the setting up of a joint public/private laboratory (GENOCOR-LAB) dedicated to the development and testing of new cost-effective technologies exploiting the growing knowledge in the genomic correlates of cardiovascular diseases (CVD) and of their evolution; the data obtained by the GENOCOR-Lab should especially orient secondary prevention and specific treatment of ischemic heart diseases (IHD).
Study to Determine the Impact of Intraoperative Blood Pressure Management on Postoperative Outcomes...
DeathPostoperative Complications3 moreThe purpose of this study is to determine whether intraoperative hypotension or hypertension is independently associated with postoperative mortality and morbidity whether quality improvement interventions implemented at the University of Michigan and at Washington University: decrease the extent and duration of intraoperative hypotension and hypertension. are associated with decreased postoperative mortality and morbidity.
Sicilian Administrative Data Base Study in Acute Coronary Syndrome Patients
Acute Coronary SyndromeAcute Myocardial InfarctionThi is an observational, non interventional, cohort analysis by using administrative databases (drugs treatment, laboratory and diagnostic tests, specialist visits and hospitalizations) of Sicilia region to evaluate treatment patterns of patients after Acute Coronary Syndrome (ACS) event.
Protective Effect of Coronary Collaterals on Infarct Size in Patients With Acute Myocardial Infarction...
Myocardial InfarctionThe hypothesis of the current proposal is that collateral flow is an important determinant of myocardial protection during an ischemic event. Increased collateral flow for any given area at risk will decrease the myocardial damage caused by the occlusion of the infarct related epicardial artery. It is further hypothesized that myocardial salvage provided by collateral flow will decrease infarct size and this in turn will decrease LV dilatation post-myocardial infarction.
Echocardiographic Examination Performed by Nurses in Cardiac Intensive Care Unit
Heart FailureMyocardial Infarction1 moreThe purpose of this study is: To study the clinical usefulness of nurse-performed ultrasound and echocardiographic examinations in a cardiac intensive care unit. To study reproducibility of nurse-performed ultrasound and echocardiographic examinations in a cardiac intensive care unit. To study which ultrasound measure that best correlate with the amount of pleural effusion.
Measurement of Matrix Metalloproteinase Activation Post Myocardial Infarction
Acute Myocardial InfarctionThis study is designed to look at the measurement and prediction of changes in the heart following a heart attack.
Evaluation of Serial Troponin and Cardiac Multimarkers at the Point of Care in the Emergency Department...
Acute Myocardial InfarctionChest Pain1 moreThis is a multi-center study to assess the diagnostic accuracy of the Troponin I assay in the Biosite Triage Cardio3 Panel at the point-of-care (POC) in adults presenting to the emergency department with possible acute myocardial infarction (AMI).
A Study to Objectively Measure Physical Activity and Sedentary Behavior During Cardiac Rehabilitation...
Cardiac DiseaseMyocardial Infarction2 moreThe purpose of this study is to assess exercise patterns during home-based or center-based cardiac rehabilitation participation.
Telerobotic Ultrasound for Carotid Imaging - Feasibility Study
Carotid Artery DiseaseAtherosclerosis18 moreIn this proposal, the investigators will demonstrate the feasibility and noninferiority of telerobotic ultrasonography as compared to traditional manual acquisition in performing a limited carotid Duplex examination and in carotid plaque detection.
Inflammation in Type 2 Myocardial Infarction
Myocardial InfarctionInflammation1 moreType 2 myocardial infarction (MI) is defined as myocardial necrosis that results from an imbalance of myocardial oxygen supply and demand. Although type 2 MI is highly prevalent in patients with critical illness and strongly associated with mortality, the pathophysiology remains poorly understood. Inflammation is central to the development of atherosclerosis, plaque rupture, and other subtypes of MI, but the role of inflammation in type 2 MI and myocardial necrosis has not been defined. The investigators aim to to delineate the mechanistic role of inflammation in myocardial necrosis and type 2 MI complicating critical medical illness.