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Active clinical trials for "Surgical Wound Infection"

Results 191-200 of 504

Wound Infection in Obese Women After Cesarean Delivery

Surgical Site Infection

The purpose of this study is to determine the surgical site infection rate and patient satisfaction for absorbable versus non absorbable suture in closure of skin at cesarean section in obese women.

Completed14 enrollment criteria

Air Barrier System for the Prevention of Surgical Site Infection

Surgical Site Infection

Airborne particles are present in all indoor environments including the operating room. Most of these particles come from the surgical staff moving around in the room, positioning of the patient during surgery, and the movement of surgical equipment and supplies. While the amount of particulate in an operating room is much, much less than is found in a typical home or public space, some particulate is usually present no matter how the room and air are cleaned and filtered. Typically these few particulate cause no problems, but the goal is always to have the cleanest air possible during surgery. The Air Barrier System (ABS) consists of a reusable blower and a sterile nozzle. The blower feeds filtered air into the sterile disposable nozzle, which disperses a constant stream of gentle, high purity air over the surgical incision. This stream of air forms a shield over the surgical area to prevent airborne particulate from settling into the open wound. This is particularly critical for long-duration surgeries, such as procedures that involve the implantation of a prosthesis. The main objective of this research study is to determine whether the ABS can reduce the potential for surgical site infection during total hip replacement, spinal fusion, or lower extremity bypass grafting procedures. These procedures were chosen because each is a long-duration procedure which involves implantation of prosthesis.

Completed4 enrollment criteria

Study of Chlorhexidine Gluconate as a Preoperative Antisepsis

Surgical Site Infection

The purpose of this study is to determine which drug (chlorhexidine gluconate vs. povidone iodine) as a preoperative antisepsis in clean-contaminated abdominal surgery (liver, hepatobiliary, small or large bowel, stomach) is effective.

Completed21 enrollment criteria

Clipping Versus No Hair Removal and the Risk of Surgical Site Infections

Surgical Site InfectionSuperficial Surgical Site Infection2 more

The objective of this study is to determine whether hair clipping is non-inferior to no hair removal in preventing superficial, deep, and organ space surgical site infections (SSI) in patients undergoing various general surgical procedures, evaluated after surgery by an assessor blinded to treatment allocation. Additional goals include evaluating wound complications that arise in patients that have hair clipped and in patients that do not have hair removed and determining the impact of clipping versus no hair removal and SSI versus no SSI on length of hospital stay.

Completed12 enrollment criteria

Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious...

Infection; Cesarean SectionSurgical Wound Infection1 more

Previous studies have demonstrated that patients who undergo surgery while they under general anesthesia have fewer wound infections if they receive higher concentrations of oxygen but this has never been studied in women who are undergoing cesarean section. We plan to randomize women who are undergoing cesarean to receive either standard of care oxygen flow through a nasal cannula during their cesarean section only or a higher concentration of oxygen than they would typically receive through a face mask. Women will receive this therapy during their cesarean and for 2 hours afterwards. We will follow them after their surgery for evidence of infection either in their wound or their uterus.

Completed6 enrollment criteria

Study of the Efficacy of Preoperative Cefuroxime Prophylaxis to Prevent Surgical Site Infection...

Surgical Wound Infection

The purpose of the study is to determine whether a single, pre-operative dose of cefuroxime is effective in preventing surgical site infection in patients undergoing surgery for herniated disk

Completed9 enrollment criteria

A Single Dose of a Marketed Drug Being Studied for a New Indication to Treat Surgical Site Infection...

Colorectal Surgery

The objective of this study is to evaluate the safety and efficacy of a one time dose of an intravenous marketed drug being evaluated for a new indication as compared to a marketed drug already approved for the prevention of surgical site infection following colorectal surgery.

Completed3 enrollment criteria

Effect of Standard Normothermia Protocol On Surgical Site Infections

Surgical Site Infection

Aim of this study is to investigate the efficiency of a standard normothermia protocol and effects on postoperative Surgical Site Infection (SSI) rate.

Completed12 enrollment criteria

Preoperative Bath in Patients Submitted to Hip Arthroplasty

Surgical Wound Infection

Clinical trial for prevention, randomized, controlled, blinded, parallel, with three arms which purpose is verify the effects of nursing intervention preoperative bathing with 4% chlorhexidine gluconate, 10% Povidone iodine (PVPI) and soap without antiseptic, for the prevention of surgical site infection (SSI) in patients undergoing hip arthroplasty.

Completed10 enrollment criteria

Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances...

Surgical Site Infection

Comparative study of antimicrobial effectiveness evaluation of of 26ml Project X, 10.5ml Project X, 5.1ml Project X and Prevantics Maxi swabstick following ASTM E1173 - Standard test method for evaluation of preoperative, precatheterization or preinjection skin preparations.

Completed20 enrollment criteria
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