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Active clinical trials for "Wound Infection"

Results 21-30 of 354

Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections...

Surgical Site InfectionCesarean Section; Infection

This will be a single-center randomized control trial comparing the efficacy of two different formulations of Chlorhexidine surgical skin preparation in preventing cesarean section wound infections. Participants will be randomized to either 4% Chlorhexidine Gluconate aqueous solution (CHG) or 2% Chlorhexidine with isopropyl alcohol (CHG-IPA) 70% to examine the risk of infectious morbidity in those undergoing cesarean delivery. There will also be a cost-effectiveness analysis of the two preoperative skin preparations.

Recruiting7 enrollment criteria

Vaginal Cleaning Using Povidone Iodine Before CS to Reduce Postoperative Wound Infection

Cesarean Section ComplicationsVaginal Infection1 more

The aim of work to assess the effectiveness of preoperative vaginal cleansing with povidone iodine on reduction of post caesarean section wound infection Research questions: Does vaginal cleaning using povidone iodine before cesarean section has effect on reduction of postoperative wound infection??

Recruiting17 enrollment criteria

Topical Vancomycin Over Sternal Edge in Cardiac Surgery

Sternal Wound Infection

This is a single-blind 1:1 randomized controlled trial based on the hypothesis that topical application of vancomycin paste over sternum edge is safe and can reduce sternal wound infection after elective cardiac surgery. Vancomycin paste will be prepared using 2.5 g of vancomycin mixed with 2 ml normal saline. Vancomycin paste as control or 2 ml normal saline as placebo will be spread on sternal edge immediately after sternotomy and before sternal closure. The safety of Vancomycin paste over sternum edge will be assessed according to postoperative serum Vancomycin exposure and potential side effects such as renal toxicity or bacterial resistance. Effect of topical Vancomycin on incidence of postoperative sternal wound infection will be assessed on postoperative 7, 30, and 90 days.

Recruiting10 enrollment criteria

Clinical Performance and Safety of Suture-TOOL

LaparotomyIncisional Hernia2 more

The goal of this single arm intervention study is to investigate the safety and performance of a suturing device for closure of the midline incision after open abdominal surgery. The study population consists of 38 patients selected for open abdominal procedures for malignant and benign colorectal disease. The main question it aims to answer is: • If the device facilitates a Suture-Length to Wound-Length (SL/WL) ratio of 4:1 Participants laparotomy wound will be closed with the device at the end of the operation and closure related data as closure time and SL/WL ratio will be calculated. The wound will be assessed for infection during the postoperative stay and the chart will be reviewed for wound dehiscence and wound infection.

Recruiting15 enrollment criteria

Evaluation of Post-discharge Surveillance Mobile Application for Surgical Site Infection

Surgical Wound Infection

Objective: evaluate the effectiveness and usability of a mobile application for post-discharge surveillance of surgical site infection as a support system for clinical decision.

Recruiting13 enrollment criteria

NPWT vs Primary Closure in SSI Prevention for Emergency Laparotomies for Peritonitis

PeritonitisSurgical Site Infection2 more

The study aims to evaluate the efficacy of negative pressure wound therapy (NPWT) compared with primary closure (PC) in surgical site infection (SSI) prevention for laparotomy for peritonitis.

Recruiting3 enrollment criteria

An Exploratory Clinical Trial to Evaluate the Efficacy and Safety of a Novel Antibacterial Bone...

Wound Infection

The goal of this clinical trial is to test in wound infection. The main question it aims to answer is: Whether this antibacterial bone traction needle is safe and has a good effect on wound infection. Participants will be implanted with an antibacterial bone traction needles and the infection grade of wound after surgery will be observed. If there is a comparison group: Researchers will compare the control group without antibacterial ability to see if the experimental group Can effectively inhibit wound infection.

Recruiting11 enrollment criteria

Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation...

AmputationAmputation; Postoperative6 more

This study is a prospective, multi-center, two-arm, unblinded, and randomized controlled trial with a goal of evaluating the impact of a closed incision negative pressure dressing (PREVENA) on incidence of post-operative wound complications and medical costs in patients undergoing lower extremity amputation.

Recruiting11 enrollment criteria

Violet-Blue Light Inactivation of Bacteria in Chronic Wounds

Phototherapy ComplicationPhotobiology3 more

This four-week prospective clinical investigation will assess the safety and feasibility of a medical device without CE-marking. The medical device is a light-emitting-diode (LED) and is manufactured by VulCur MedTech Aps. Violet-blue light treatment is tested on a total of twenty-two patients with chronic wounds, divided into three groups, each group only receiving one dosage. Three dosages (low, medium and high) of violet-blue light treatment is tested. ID 1-7 are assigned to the low group, ID 8-15 are assigned to medium group and ID 16-22 are assigned to the high dosage group.

Recruiting17 enrollment criteria

Delayed vs Early Enteral Feeding After Anterior Sagittal Anorectopexy

Onset of Perineal Wound Infection

to study the effect of early vs delayed enteral feeding following ASARP in females with congenital recto-vestibular fistula

Enrolling by invitation2 enrollment criteria
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