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Active clinical trials for "Skin Diseases, Infectious"

Results 31-40 of 91

Safety and Efficacy Study of a Fluoroquinolone to Treat Complicated Skin Infections

Skin Structure InfectionsBacterial Skin Diseases1 more

The purpose of this study is to assess the efficacy, safety and tolerability of RX-3341 (delafloxacin), a fluoroquinolone, versus tigecycline, a glycylcycline antibacterial drug, in the treatment of complicated skin and skin structure infections.

Completed13 enrollment criteria

Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections

Infectious Skin DiseasesBacterial Skin Diseases3 more

The purpose of this study is to assess the efficacy, safety and tolerability of RX-1741, an oxazolidinone, versus linezolid, another oxazolidinone, in the treatment of uncomplicated skin and skin structure infections

Completed36 enrollment criteria

A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in...

Skin DiseasesInfectious1 more

The purpose of this study is to evaluate the safety and effectiveness of levofloxacin, an antibiotic, compared with ciprofloxacin, another antibiotic, in the treatment of adults with mild to moderate infections of the skin and the supportive layers beneath the skin.

Completed8 enrollment criteria

Staphylococcus Aureus Decolonization Study

Staphylococcal Skin InfectionsAbscesses3 more

The purpose of this study is to determine whether measures to eliminate the Staph germ from the skin of the index patient (with a special ointment and soap) are more effective when performed by everyone in the household rather than the patient alone, and whether these methods are effective in preventing future Staph infections. The investigators hypothesize that there will be a greater number of households who are successful in eradicating the staph germ from the index patient when all members of the household participate than households where only the index patient is treated.

Completed10 enrollment criteria

Effective Antibiotic Treatment of MRSA

Skin DiseasesInfectious

To evaluate the effective duration (in days) to clinical improvement of outpatient antibiotic regimens in the treatment of superficial abscesses caused by MRSA in patients that present to the emergency department.

Completed5 enrollment criteria

Study the Efficacy and Safety of PTK 0796 in Patients With Complicated Skin and Skin Structure Infection...

Infectious Skin DiseaseBacterial Skin Disease

A Phase II trial to demonstrate the safety and efficacy of PTK 0796 in the treatment of complicated skin and skin structure infections (cSSSI).

Completed7 enrollment criteria

Safety, Efficacy, and Pharmacokinetics (PK) of Daptomycin (MK-3009) in Japanese Pediatric Subjects...

BacteremiaSoft Tissue Infections2 more

The purpose of this study is to assess the safety, efficacy and pharmacokinetic (PK) parameters of daptomycin for injection in Japanese pediatric participants aged 1 to 17 years with complicated skin and soft tissue infection (cSSTI) or bacteremia caused by gram-positive cocci.

Completed25 enrollment criteria

Cold Atmospheric Plasma Device for Pediatric Molluscum and Verruca

Verruca VulgarisMolluscum Contagiosum Skin Infection

This study is going to test a cold atmospheric plasma device (CAP), in particular a floating electrode-dielectric barrier device (FE-DBD), to treat warts and molluscum. The treatment device in this study generates cold atmospheric plasma (gaseous ionized molecules) to rid the virus from the body. Based on the successes of previous dermatologic studies, FE-DBD is being tested for this study to treat warts and molluscum. Patients will be enrolled to test the efficacy and safety of this device. The duration of the study is 4-12 weeks depending on treatment clearance. The number of lesions will be chosen by the dermatologist. Patients will receive standard of care therapy and/or NTAP depending on the number of lesions.

Completed9 enrollment criteria

Cantharidin and Occlusion in Verruca Epithelium

Common WartWarts Hand12 more

This is a Phase 2, open label study (Study number VP-102-105; referred to as COVE-1 [Cantharidin and Occlusion in Verruca Epithelium]) to evaluate the efficacy, safety and tolerability of VP-102 treatment in subjects with common warts. This study has two Cohorts.

Completed30 enrollment criteria

Efficacy and Safety Study of Brilacidin to Treat Serious Skin Infections

Skin InfectionBacterial Infection

The purpose of this study is to determine the safety and efficacy of three different dosing regimens of brilacidin compared to daptomycin for the treatment of serious skin infections. This study will aid in selecting the appropriate dose of brilacidin for later stage studies.

Completed36 enrollment criteria
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