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Active clinical trials for "Crohn Disease"

Results 491-500 of 1510

Healthy Approach to Physical and Psychological Problems in Youngsters With IBD (HAPPY-IBD).

Inflammatory Bowel Disease (IBD)Ulcerative Colitis3 more

The presented study aims to reduce symptoms of depression and anxiety in adolescents with inflammatory bowel disease and increased symptoms of anxiety and depression by using the disease specific CBT program (PASCET-PI)in order to improve quality of life and to improve the clinical course of disease.

Completed11 enrollment criteria

Impact of Exclusive Enteral Nutrition Therapy on Sperm Quality of Patients With Crohn's Disease...

Crohn's Disease

The purpose of this study is to investigate the impact of enteral nutrition therapy on sperm quality of patients with crohn's disease.

Completed8 enrollment criteria

A Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Moderately to...

Crohn's Disease

The objective of this study is to evaluate the efficacy and safety of upadacitinib compared to placebo as induction therapy in participants with moderately and severely active Crohn's disease (CD).

Completed11 enrollment criteria

5-HTP in Patients With IBD in Clinical and Biologic Remission:Effect on Fatigue Scores

Crohn DiseaseUlcerative Colitis2 more

This placebo cross-over trial aims to study the effect of the oral intake of an essential amino-acid 5-OH tryptophan, the precursor of serotonin, on the fatigue scores in IBD patients in deep clinical and biological remission.

Completed21 enrollment criteria

Adipose Tissue in Crohn´s Disease Fistulas

Crohn DiseasePerianal Fistula1 more

Present study investigated the efficacy of injection of freshly collected autologous adipose tissue into perianal fistulas in patients with Crohn's disease. Adipose tissue collected by liposuction was injected into the perianal fistulas. Primary objective was complete clinical healing six months after treatment. Secondary objectives were reduced or ceased fistula secretion and complications to the treatment.

Completed4 enrollment criteria

Yoga for Youth With IBD: a Pilot Feasibility Study

Inflammatory Bowel DiseasesYoga3 more

An 8-week yoga intervention to determine the feasibility and acceptability of yoga as a supplemental therapy in the management of inflammatory bowel disease in the adolescent population.

Completed12 enrollment criteria

Vitamin D Regulation of Gut Specific B Cells and Antibodies Targeting Gut Bacteria in Inflammatory...

Inflammatory Bowel DiseasesUlcerative Colitis1 more

Specific Aim 1: Characterize the effects of vitamin D treatment on expression of α4β7 on B cells in patients with inflammatory bowel disease (IBD). Specific Aim 2: Determine the effects of vitamin D treatment on fecal immunoglobulins, percentage of Ig-coated gut bacteria, gut microbiome composition (global and bound by immunoglobulins) in patients with IBD and the association of these parameters with change in α4β7+ B cells . Specific Aim 3: Compare BCR repertoire (BCR clonotypes, immunoglobulin heavy chain gene (IGHV), and isotype usage) between α4β7+ and α4β7- B cells in patients with IBD and identify α4β7+ BCR clonotypes associated with Ig-bound gut bacteria .

Completed17 enrollment criteria

A Study to Evaluate the Long-term Safety and Efficacy of Deucravacitinib in Participants With Crohn's...

Crohn DiseaseUlcerative Colitis

The purpose of this study is to evaluate the long-term safety and efficacy of Deucravacitinib in participants who have previously been enrolled in a Deucravacitinib Phase 2 study for moderate to severe Crohn's disease or moderate to severe Ulcerative Colitis.

Completed4 enrollment criteria

The NOR-SWITCH Study

Rheumatoid ArthritisSpondyloarthritis4 more

The purpose of this study is to assess the safety and efficacy of switching from Remicade to the biosimilar treatment Remsima in patients with rheumatoid arthritis, spondyloarthritis, psoriatic arthritis, ulcerative colitis, Crohn's disease and chronic plaque psoriasis

Completed13 enrollment criteria

Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Two Treatment Modules in Chinese...

Crohn's Disease

The purpose of this study is to investigate the efficacy, safety, and pharmacokinetics of adalimumab following subcutaneous (SC) administration of 2 dosing regimens in Chinese subjects with Crohn's disease.

Completed11 enrollment criteria
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