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Active clinical trials for "Wounds and Injuries"

Results 4571-4580 of 4748

Are the Pancreatic Serum Proteins Pancreatic Stone Protein (PSP) and Pancreatitis-Associated Protein...

Trauma Patients With Soft Tissue Defects

Retrospective analysis of PSP- and PAP-serum levels in trauma patients with soft tissue defects and possible correlation with the incidence and onset of infection and sepsis.

Unknown status2 enrollment criteria

Positron Emission Tomography (PET) in Evaluating Cerebral Glucose Metabolism and Functional Change...

Spinal Cord Injury

Background: Spinal cord injury (SCI) results in dysfunction of motor and sensory system and the hormonal secretion. Not only the change of peripheral hormonal organs, the central neurotransmitters were also affected. We consider there are some changes in cerebral physiology, anatomy or function after SCI. Objective: Use PET imaging to investigate the brain functional difference among the SCI and control group.

Unknown status8 enrollment criteria

Study of Sand Versus Wood Chip Surfaces on School Playgrounds to Minimize Injury in School Children...

Wounds and InjuriesClosed Head Injury

This study will compare children's injury rates (arm fracture, head injury and other injuries) when playing on playground equipment on granite sand versus wood fibre playing surfaces. The hypothesis is that injury rates (arm fracture, head injury and other injuries) among school children are equal on granite sand and wood fibre playground surfaces.

Unknown status4 enrollment criteria

Clinical Evaluation of the SNaP Wound Care System in Promoting Healing in Chronic Wounds

Lower Extremity Diabetic Leg WoundsLower Extremity Venous Leg Wounds1 more

The purpose of this study is to evaluate a novel topical negative pressure (TNP) wound therapy device called the SNaP® (Smart Negative Pressure) Wound Care System for the treatment of lower extremity diabetic, venous and mixed aetiology leg wounds.

Withdrawn15 enrollment criteria

The Role of Splinting in Fingertip Injuries

Injury Distal to Flexor and Extensor Tendon Insertions

This study is attempting to understand whether or not splinting after a fingertip injury improves recovery.

Withdrawn5 enrollment criteria

Hematologic Ratios in Postoperative Acute Kidney Injury

Acute Kidney Injury

Acute kidney injury (AKI) is a common complication after surgery for congenital heart disease and is associated with significant morbidity and mortality. To-date, no biomarker has been universally implemented for predicting AKI in neonates after cardiac surgery. In this study, the use of hematological ratios will be evaluated for predicting AKI and postoperative outcomes in this patient cohort.

Withdrawn9 enrollment criteria

Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired...

DementiaTraumatic Brain Injury (TBI)3 more

The objective of this study is to measure the frequency and clinical types of mild cognitive impairment (MCI) or dementia that occur among up to 150 military retirees with and without a history of traumatic brain injury (TBI) among residents of the Armed Forces Retirement Home, Washington D.C. and the Veterans Home of California-Yountville. Investigators will compare the characteristics of dementia in those who have had a prior TBI to the characteristics in those without a history of TBI. It is our hypothesis that the dementia or MCI among those with prior TBI has distinct neuropsychological features that distinguishes it from those with dementia or MCI without a history of TBI.

Withdrawn20 enrollment criteria

Evaluation of Wound Biofilm in Acute and Chronic Wounds

Wounds

Patients who present to a wound care center for management of their wounds will be evaluated clinically to establish if their wounds are chronic or acute. These patients will undergo standard of care management of their wounds. If debridement is indicated for the patient, the patient will be asked to participate in a study. Once the standard of care debridement is complete, the material debrided from the wound, instead of being discarded into a biohazard bag, will be prepared for shipment. The samples will then be shipped to the Center for Biofilm Engineering where microscopic evaluation will be conducted on the material. Conclusion will be made from that analysis.

Withdrawn0 enrollment criteria

The Role and Mechanism of Immune Regulation in Acute Lung Injury in Children

Acute Lung Injury

Acute lung injury is a highly prevalent disease in children, posing a serious threat to their health and causing economic burden on society and families. It has received high attention. Blocking the cascade immune inflammatory response that occurs in the respiratory tract and finding key targets for the prevention and treatment of acute lung injury has become an important challenge faced by the medical community. The pathogenesis of acute lung injury is complex, involving the combined action of multiple cells and cytokines in the immune system. Therefore, it is necessary to further study the function of immune cells and specific immune pathogenesis, providing new ideas and theoretical basis for clinical treatment of acute lung injury. The omics technology includes Genomics, Transcriptome, proteomics, metabolomics, etc. Through qualitative and quantitative analysis of changes in low molecular weight molecules or metabolites of biological samples, it provides a new way to find biomarkers and pathogenesis. We plan to study the peripheral blood of children with acute lung injury and healthy children, and use network analysis to screen for differential genes and related enrichment pathways in acute lung injury. We aim to explore the correlation between immune regulation and inflammatory repair in children with acute lung injury, and analyze the regulatory mechanisms between immune cells related to it. Provide assistance for clinical diagnosis and treatment.

Withdrawn5 enrollment criteria

Diffusion Tensor Imaging to Assess the Functional Outcomes of Adults With Cervical Spinal Cord Injuries...

Cervical Spinal Cord Injury

Acute changes in axial diffusivity will correlate with the severity of injury in patients that suffer an acute spinal cord injury.

Withdrawn9 enrollment criteria
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