
Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal...
AppendicitisCholecystitis4 moreThis is a study of the safety and efficacy of tigecycline to ceftriaxone sodium plus metronidazole in hospitalized subjects with cIAI. Subjects will be followed for efficacy through the test-of-cure assessment. Safety evaluations will occur through the treatment and post-treatment periods and continue through resolution or stability of the adverse event(s).

Doripenem in the Treatment of Complicated Intra-Abdominal Infections
Bacterial Infections and MycosesAppendicitis3 moreThe purpose of this study is to compare the clinical response rate of doripenem versus a comparator in the treatment of hospitalized patients with complicated intra-abdominal infections.

A Safety and Efficacy Study of Doripenem in Participants With Nosocomial Pneumonia, Complicated...
InfectionCross Infection5 moreThe purpose of this study is to assess the safety and efficacy of doripenem in participants with nosocomial pneumonia (inflammation of the lungs in which the lungs become heavy; pneumonia occurring at least 48 hours after hospital admission), complicated intra-abdominal (in belly) infections and complicated urinary tract infections (bladder infections).

Therapy of Complicated Intra-Abdominal Infections With Moxifloxacin or Ertapenem
InfectionA study to compare the safety and efficacy of moxifloxacin to ertapenem in patients with intra-abdominal infections.

An Investigational Agent for the Treatment of Complicated Intra-Abdominal Infections or Acute Pelvic...
InfectionsPelvic InfectionsThe purpose of this study is to determine the effect of an approved medication for adults for an investigational use in pediatric patients 3 months to 17 years for the treatment of complicated intra-abdominal infections or acute pelvic infections.

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of...
Gram-negative Bacterial InfectionsBloodstream Infections (BSI)5 moreThe primary objectives of this study are: To assess the safety and tolerability of cefiderocol after single-dose administration in hospitalized paediatric participants 3 months to < 18 years of age with suspected or confirmed aerobic Gram-negative bacterial infections To assess the pharmacokinetics (PK) of cefiderocol after single-dose administration of cefiderocol in hospitalized paediatric participants 3 months to < 18 years of age with suspected or confirmed aerobic Gram-negative bacterial infections To assess the safety and tolerability of cefiderocol after multiple-dose administration in hospitalized paediatric participants 3 months to < 12 years of age with suspected or confirmed aerobic Gram-negative bacterial infections To assess the PK of cefiderocol after multiple-dose administration in hospitalized paediatric participants 3 months to < 12 years of age with suspected or confirmed aerobic Gram-negative bacterial infections

A Study To Determine The Efficacy And Safety Of Tigecycline Compared With Imipenem/Cliastatin to...
Intra-abdominal InfectionThis is a comparative study of the efficacy and safety of tigecycline to imipenem/cilastatin in hospitalized patients with a complicated intra-abdominal infection.

Study to Compare TP-434 and Ertapenem in Community-acquired Complicated Intra-abdominal Infections...
Complicated Intra-abdominal InfectionThis is a Phase 2, randomized, double-blind, double-dummy, multicenter, prospective study to assess the efficacy, safety, and pharmacokinetics of two dose regimens of TP-434 compared with ertapenem in the treatment of adult community-acquired complicated intra-abdominal infections (cIAIs).

Blood Indices of Systemic Inflammation in Critically Ill Patients With Abdominal Sepsis
Abdominal SepsisCritically IllThis study aims to clarify the role of blood indices of systemic inflammation in ICU-admitted patients with abdominal sepsis to assess their diagnostic significance as well as their prognostic value.

A Comparative Study of Ampicillin/Sulbactam Versus Moxifloxacin in the Treatment of Complicated...
Intra-abdominal InfectionOn the basis of monotherapy for intra-abdominal infection, the investigators are conducting this study to identify the difference of drug efficacy between ampicillin/sulbactam and moxifloxacin.