Endpoint Determination Study Protocol
Irritable Bowel SyndromeThis study is designed to evaluate the most applicable endpoints for evaluation of the Biomerica InFoods® IBS product.
SMART Program in Irritable Bowel Syndrome (IBS)
Irritable Bowel SyndromeThis is a pilot study to determine the efficacy of the Stress Management and Resilience Training (SMART) program in improving gastrointestinal and psychological symptoms, health-related quality of life, and satisfaction of care in patients with irritable bowel syndrome (IBS). Half of the participants will be enrolled in the SMART program initially. The other half will be placed in a self-management stress reduction program where they will read a popular stress reduction book over 12 weeks. Then they will have access to participate in the online SMART program.
Multi-strain Probiotic in the Management of IBS-D
Irritable Bowel SyndromeTo assess the effect of multistrain probiotics on abdominal pain using a validated symptom severity score in IBS patients. To assess the efficacy of a multi-strain probiotic supplement as a treatment option for IBS in a tertiary referral centre
Efficacy and Safety of a Food Supplement With Standardized Menthol, Limonene, and Gingerol Content...
Irritable Bowel SyndromeIrritable Bowel Syndrome With Diarrhea2 moreThe purpose of this study is to assess the efficacy and safety of a food supplement with standardized menthol, limonene, and gingerol content in patients with irritable bowel syndrome (IBS) or IBS/functional dyspepsia (FD).
Efficacy and Safety of Rifaximin With NAC in IBS-D
Irritable Bowel Syndrome With DiarrheaRandomized, prospective proof of concept, double-blind, single site clinical trial to determine the efficacy of combined rifaximin and N-acetylcysteine (NAC) therapy vs. rifaximin alone in decreasing clinical symptoms in subjects with IBS-D.
The Effects of Bifidobacterium Breve Bif195 for Diarrhea-predominant Irritable Bowel Syndrome
Irritable Bowel SyndromeThe purpose of this study is to investigate if the probiotic Bifidobacterium breve Bif195 (Bif195) will result in improvement in clinical outcome in patients with diarrhea-predominant irritable bowel syndrome (IBS).
Plant Exosomes +/- Curcumin to Abrogate Symptoms of Inflammatory Bowel Disease
Irritable Bowel DiseaseThe trial will test the hypothesis that edible structures within plant cells (ginger) will have clinically important anti-inflammatory effects on the gut lining of patients with inflammable bowel disease. To evaluate the safety and tolerability of exosomes with and without curcumin in patients with Inflammatory Bowel Disease (IBD); To estimate the effect of ginger exosomes or curcumin alone or combined with curcumin on the symptoms and disease score in patients with refractory IBD describe toxicities associated with ginger exosomes; to evaluate the effect of ginger exosomes on biomarkers of inflammation.
Aldafermin (NGM282) for Chronic Diarrhea Due to Bile Acid Malabsorption (BAM)
Chronic DiarrheaIrritable Bowel Syndrome With Diarrhea4 moreThis single-center, randomized, double-blind, placebo-controlled study is designed to compare effects of aldafermin, (NGM282), 1 mg, and placebo given daily by subcutaneous injection on bowel functions and hepatic synthesis and fecal excretion of bile acids in patients with diarrhea associated with bile acid malabsorption (BAM).
Treatment of IBS in Primary Health Care.
Irritable Bowel SyndromeThe purpose of this study is to retrospectively evaluate treatment strategies for IBS used within primary Health care in Örebro Region.
Targeted Metabolomics to Decipher Dietary Contributions to Pediatric Inflammatory Bowel Disease...
Gut MicrobiomeInflammation1 moreThe overall goal of the study is to investigate the dietary differences between children with well-controlled inflammatory bowel disease (IBD) and those with active disease by using targeted food metabolomics. The utilization of the application of targeted metabolomics allows for the investigation of specific components of foods and their effects in IBD and inflammation, which may inform future dietary recommendations for IBD patients.