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Active clinical trials for "Macular Edema"

Results 171-180 of 850

Conbercept Ophthalmic Injection for Patients With Macular Edema Caused by Branch Retinal Vein Occlusion...

Branch Retinal Vein OcclusionMacular Edema

The purpose of this study is to verify the efficacy and safety of intravitreal injection of conbercept in patients with macular edema (ME) caused by branch retinal vein occlusion (BRVO).

Completed46 enrollment criteria

Conbercept Ophthalmic Injection for Patients of Central Retinal Vein Occlusion

Macular EdemaCentral Retinal Vein Occlusion

This study evaluates the efficacy and safety of Conbercept ophthalmic injection. This is a multi-center, randomized, double-masked, placebo-controlled phase III clinical study. 237 patients with central retinal vein occlusion(CRVO) are expected to be enrolled in the study and randomly assigned into the Conbercept ophthalmic injection treatment group or the control group at a ratio of 2:1.

Completed47 enrollment criteria

3 Month Outcome of Ziv-aflibercept for DME

Diabetic Macular Edema

The purpose is to show the 3-month efficacy and safety in diabetic macular edema treated with intravitreal ziv-aflibercept.

Completed11 enrollment criteria

Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular...

Macular EdemaRetinal Vein Occlusion

A phase 2, multicenter, randomized, active-controlled, masked, parallel arm study designed to evaluate the safety and efficacy of a single suprachoroidal injection of CLS-TA, triamcinolone acetonide injectable suspension, given along with an intravitreal (IVT) injection of aflibercept compared to IVT aflibercept alone in subjects with retinal vein occlusion (RVO).

Completed6 enrollment criteria

Variable Interval Versus Set Interval Aflibercept for DME

Cystoid Macular EdemaDiabetic Macular Edema

The purpose of this study is to compare the safety and efficacy of intravitreal Eylea injections at a set interval, versus a variable dosing schedule (likely longer than one month), based on a specific individual's disease progression. There will be approximately 50 men and women at least 18 years of age, diagnosed with type 1 or type 2 diabetes, taking part in this study at 5 locations in the United States.

Completed34 enrollment criteria

Exploratory Study of KPI-121 Effect on Intra- or Subretinal Fluid Due to Retinal Vein Occlusion/Diabetic...

Retinal Vein OcclusionDiabetic Macular Edema

The primary objectives of the study are to evaluate the safety and effect of KPI-121 0.25% ophthalmic suspension and KPI-121 1.0% ophthalmic suspension on intraretinal or subretinal fluid secondary to Retinal Vein Occlusion or Diabetic Macular Edema.

Completed8 enrollment criteria

A Study of Abicipar Pegol in Patients With Diabetic Macular Edema

Macular Edema

This is a safety and efficacy study of abicipar pegol in patients with diabetic macular edema.

Completed7 enrollment criteria

A Phase I Single Ascending Dose Study of the Intravitreal Plasma Kallikrein Inhibitor KVD001 in...

Diabetic Macular Edema

This is a Phase 1 study to investigate the safety, tolerability of the novel plasma kallikrein inhibitor, KVD001 in subjects with diabetic macular edema. The study is the first step to investigate the hypothesis that plasma kallikrein plays an important role in the disease process behind diabetic macular edema in many patients

Completed24 enrollment criteria

Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious...

UveitisMacular Edema7 more

The study is designed to evaluate the safety and efficacy of triamcinolone acetonide, CLS-TA, in subjects with macular edema following non-infectious uveitis. A single suprachoroidal injection of one of two doses of CLS-TA will each be evaluated in subjects with macular edema following non-infectious uveitis.

Completed7 enrollment criteria

Multiple Dose Safety and Efficacy of LKA651 in Patients With Diabetic Macular Edema

Diabetic Macular Edema

The primary objectives of this study were to evaluate the safety and efficacy of LKA651 in patients with macular edema from diabetic macular edema (DME),

Completed15 enrollment criteria
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