A Clinical Evaluation of the MINI TREK RX 1.20 mm Coronary Dilatation Catheter in Stenotic Lesions...
Ischemic Heart DiseaseCoronary Artery Stenosis2 moreThis is a prospective, single-arm, open-label, multi-center, observational study to assess the acute safety and efficacy of MINI TREK RX 1.20 mm, for descriptive purposes only.
Effect of Folic Acid Treatment in Coronary Artery Disease
Coronary Artery DiseaseWe seek to examine the effects of folic acid treatment on vascular function in patients with coronary artery disease. Our hypothesis is that folic acid treatment will improve vascular function
Heart Function and Exercise Capacity in Patients With Hypertrophic Cardiomyopathy
AnginaUnstable2 moreThis study will examine the relationship between certain measures of heart function and exercise capacity in patients with hypertrophic cardiomyopathy (HCM). Patients who participated in NHLBI studies 01-H-0006 ("Double Blind Placebo-Controlled Study of Pirfenidone - A Novel Anti-Fibrotic Drug - in Symptomatic Patients with Hypertrophic Cardiomyopathy Associated with Left Ventricular Diastolic Dysfunction") and 96-H-0144 ("Double Blind Placebo-Controlled Study of Long-Term Effects of Angiotensin-Converting Enzyme Inhibition (Enalapril) and Angiotensin II Receptor Blockade (Losartan) on Genetically-Induced Left Ventricular Diastolic Dysfunction") are eligible for this study. Data from echocardiograms and measures of left ventricular pressure obtained from patients in those studies will be analyzed in the current study to assess their influence on exercise capacity. No additional tests, treatments or other procedures are required. Information from this study may help in the development of improved drug treatments for HCM.
The WOMEN Study: What is the Optimal Method for Ischemia Evaluation in WomeN?
Coronary Artery DiseaseHeart Disease3 moreThe purpose of this study is to compare two types of exercise stress testing to find the best method for detecting heart disease in women.
Comparison of Cardiac Computed Tomography for the Detection of Coronary Artery Disease With Nuclear...
Coronary ArteriosclerosisTo compare the efficacy of 16-row multi-detector CT (MDCT) with standard myocardial perfusion imaging in detecting coronary artery disease (CAD) in patients without a previously established diagnosis of CAD.
Effect of Remote Ischemic Preconditioning on Cognitive Function After Off-Pump Coronary Artery Bypass...
Ischemic Heart DiseaseThe aim of this study is to evaluate the effects of remote ischemic preconditioning on cognitive function in patients undergoing off-pump coronary artery bypass graft.
Coronary Heart Disease Incidence: Depression & Inflammation Risk
Cardiovascular DiseasesCoronary Disease3 moreTo examine the associations among depression, inflammation, and coronary heart disease using an existing data base and associated plasma samples.
Efficacy of the CMI Magnetocardiograph in Diagnosing Acute Coronary Syndromes in Patients Presenting...
Myocardial IschemiaA magnetocardiograph (MCG) is a device capable of recording of magnetic fields arising from the electrical activity of the heart with traces similar to an electrocardiogram (ECG). This system was developed as a noninvasive, non-contact diagnostics of obstructive coronary artery disease (CAD), and especially of lack of oxygen in the heart as in a heart attack. The overall objective of this study is to demonstrate the efficacy of this MCG device for the detection and diagnosis of lack of oxygen of the heart in patients with chest pain.
ARISE - Aggressive Reduction of Inflammation Stops Events
AtherosclerosisCoronary Artery Disease2 moreTo assess the safety and efficacy of AGI-1067, as compared to placebo, in the treatment of vascular inflammation and atherosclerosis by assessing the reduction in cardiovascular events.
Estrogen Receptor Variants, HDL, and Atherosclerosis
Cardiovascular DiseasesAtherosclerosis2 moreTo measure the association between estrogen receptor variants and the extent of atherosclerosis in the thoracic and abdominal aorta and the right coronary artery in subjects in the PDAY study.