The Association of Platelet Function and Endothelial Function of the Brachial Artery
Coronary Artery DiseaseEndothelial Function1 moreThe proposed study is a prospective one, and will be held on consecutive individuals undergoing the non-invasive brachial artery flow-mediated dilation (FMD) ultrasound for endothelial function at the endothelial function laboratory of the Sheba Medical Center. The study group will be divided into healthy subjects group and coronary artery disease (CAD) patients group, both of which will be analyzed in respect to age, cardiovascular risk factors and the results of the platelet and endothelial functions tests. The association between platelet and endothelial functions will be then assessed in the healthy subjects group and in the CAD patients group.
Serum Sex Hormone Levels and Subclinical Atherosclerosis - Ancillary to MESA
Cardiovascular DiseasesAtherosclerosis3 moreTo assess the associations of serum sex hormones with the presence and progression of subclinical atherosclerosis.
Ventricular Size and Value Calcification Measures by Computed Tomography - Ancillary to MESA
Cardiovascular DiseasesHeart Diseases2 moreTo rescan 6,700 subjects in the MESA study to obtain computed tomography measures of calcification.
Evaluation of Low Literacy CVD Nutrition Education
Cardiovascular DiseasesHeart Diseases1 moreTo develop and evaluate a nutrition education program to reduce cardiovascular disease risk in persons with low literacy skills.
Epidemiology of Coronary Calcification in the Elderly
Cardiovascular DiseasesHeart Diseases3 moreTo investigate the prevalence and prognostic value of subclinical atherosclerosis in the Pittsburgh SHEP cohort and a cohort of normal controls.
Myocardial Perfusion, Risk Factors, and Coronary Calcium
Cardiovascular DiseasesCoronary Arteriosclerosis2 moreTo determine whether an impairment of myocardial perfusion reserve is an early indicator of coronary artery disease.
Atherosclerosis Risk in Communities (ARIC)
AtherosclerosisCoronary Disease7 moreTo measure associations of established and suspected coronary heart disease risk factors with both atherosclerosis and new coronary heart disease events in representative cohorts from four diverse United States communities. To compare the communities with respect to risk factors, medical care, atherosclerosis, and coronary heart disease incidence. ARIC has two components in each community: study of representative cohorts of adult men and women, and community surveillance of morbidity and mortality.
Epidemiology of Atherosclerosis
AtherosclerosisCardiovascular Diseases2 moreTo determine the role of genetic factors in predicting resistance and susceptibility to coronary artery disease.
Validation and Field Test for Risk Appraisal Instruments
Cardiovascular DiseasesHeart Diseases1 moreTo field test the validity, reliability, cost, and cost-benefit of Health Risk Appraisal (HRA) instruments.
Apolipoprotein Polymorphisms and Risk of Coronary Heart Disease
Cardiovascular DiseasesHeart Diseases2 moreTo determine the relative risk in a defined population of angiographically demonstrated coronary artery disease due to genetic polymorphisms at the four apolipoprotein genomic regions.