search

Active clinical trials for "Myocardial Ischemia"

Results 3131-3140 of 3152

Prevalence of Coronary Artery Disease in the Siblings of Premature Coronary Heart Disease

Coronary Heart Disease

The aim of this prospective study is to investigate the prevalence of coronary artery disease using computed tomography with family history of premature coronary heart disease

Unknown status6 enrollment criteria

Genetic Predisposition of Coronary Artery Disease -- The COROGENE-Study

Coronary DiseaseInflammation

The aim of this study is to identify genetic loci,or gene variations contributing to inflammation and to the development of CHD. We will compare coronary angiogram results to genetic findings within coronary artery disease patients and in patients with normal coronaries.

Unknown status2 enrollment criteria

Melatonin Treatment and Inflammation, Oxidative Stress and Autonomic Function in Connection With...

Oxidative StressInflammatory Stress1 more

The purpose of this study is to determine whether treatment with melatonin can reduce cell damage and inflammation in connection with laparoscopic gall bladder surgery.

Unknown status17 enrollment criteria

IVUS VS CAG Guided PCI for Patients With LMB Lesion

Coronary Artery DiseaseLeft Main Coronary Artery Disease

To compare the 3 - year clinical follow - up results of patients with left main bifurcation lesions treated by intravascular ultrasound(IVUS) - guided and coronary angiography(CAG) - guided percutaneous coronary intervention(PCI), and to confirm the clinical benefits of optimizing interventional therapy of left main bifurcation lesions by intravascular ultrasound(IVUS).

Unknown status22 enrollment criteria

Quantitative Stress Echocardiography to Diagnose Myocardial Ischaemia

IschemiaMyocardial

Patients with chest pain on exertion need a reliable non-invasive test to identify if they have inducible myocardial ischaemia. This would reduce the use of diagnostic coronary arteriography, avoid its risks and costs, and guide clinical decisions. Conventional stress echocardiography has poor reproducibility because it relies on qualitative and subjective interpretation. Quantitative approaches based on precise and reliable measurements of myocardial velocity, strain, strain rate and global longitudinal strain have been shown to be able to accurately diagnose myocardial ischaemia. A more accurate test using myocardial velocity imaging was not implemented by ultrasound vendors although it provided an objective measurement of myocardial functional reserve on a continuous scale from normality to severe ischaemia. The investigators propose an original approach to create a diagnostic software tool that can be used in routine clinical practice. The investigators will extract and compare quantitative data obtained through myocardial velocity imaging and speckle tracking in subjects who undergo dobutamine stress echocardiography. The data will be analysed using advanced computational mathematics including multiple kernel learning and joint statistics applied to multivariate data across multiple dimensions (including velocity, strain and strain rate traces). This approach will be validated against quantitative coronary arteriography and fractional flow reserve. The results will be displayed as parametric images and placed into a reporting tool. The output will determine the presence and severity of myocardial ischaemia. These new tools will have the capacity for iterative learning so that the precision of the diagnostic conclusions can be continuously refined.

Unknown status2 enrollment criteria

Coronary Artery Geometry and the Severity of Coronary Atherosclerosis

Coronary Artery DiseaseAtherosclerosis2 more

The purpose of this study is to investigate the potential association of coronary artery geometry, based on coronary CT angiography (CCTA), with the complexity and the severity of coronary atherosclerosis.

Unknown status8 enrollment criteria

Evaluation of Inflammatory Markers and Periodontal Viruses on Periodontitis Patients With CAD

PeriodontitisCoronary Artery Disease

To assess and compare the demographic variables, periodontal parameters, cardiac parameters and the expression of periodontal viruses (CMV, HSV and EBV) and inflammatory biomarkers(PTX-3, TLR-2 & TLR-4) in periodontally healthy and generalized periodontitis patients with and without coronary artery disease(CAD).

Unknown status13 enrollment criteria

Prediction of Coronary Artery Disease Severity by Epicardial Adipose Tissue Thickness

Myocardial Infarction

is to test the hypotheses that epicardial adipose tissue can be a marker of severity of coronary artery disease in myocardial infarction patients

Unknown status7 enrollment criteria

Adipokines of Epicardial Adipose Tissue and Atherosclerosis of Coronary Arteries

Coronary AtherosclerosisAdipokines

The aim of the study is to investigate whether the expression and production of adipokines secreted by the epicardial adipose tissue correlate with the degree of coronary atherosclerosis.

Unknown status13 enrollment criteria

the Change of Cholesterol Efflux Capacity and Coronary Artery Disease in Real Clinical Practice...

Coronary Artery DiseaseCardiovascular Mortality2 more

The purpose of this study is to investigate the change of cholesterol efflux capacity in patients with coronary artery disease treated with secondary prevention drugs, and the correlation with the prognosis.

Unknown status2 enrollment criteria

Need Help? Contact our team!


We'll reach out to this number within 24 hrs