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Active clinical trials for "Keratoconjunctivitis Sicca"

Results 491-500 of 779

Study of the Effect of Diquafosol Tetrasodium Ophthalmic Solution, 2% Versus Placebo in Dry Eye...

Dry Eye Disease

The purpose of this pilot study is to evaluate the effect of diquafosol tetrasodium Ophthalmic Solution, 2% in dry eye subjects.

Completed11 enrollment criteria

Lid Margin And Conjunctival Microbial Flora Following Punctum Occlusion

Dry Eye Syndrome

To determine if the types and amount of bacteria or other germs change over time after the routine procedure of blockage of tear drainage duct in the treatment of dry eye condition or other condition benefiting from a tear drainage blockage

Completed6 enrollment criteria

Phase 2 Study of KLS-0611 in Patients With Dry Eye Syndromes

Dry Eye Syndromes

To evaluate the efficacy and safety of KLS-0611 compared to placebo in patients with dry eye syndromes.

Completed5 enrollment criteria

A Prospective, Randomized, Placebo and Active Comparator Controlled Study of CP-690,550 in Subjects...

Dry Eye Syndromes

A prospective, randomized, placebo and active comparator controlled study of CP-690,550 in subjects with dry eye.

Completed5 enrollment criteria

A Dose-Escalation Study to Assess the Safety and Tolerability of LX214 Ophthalmic Solution in Healthy...

Keratoconjunctivitis Sicca

This is a first-in-man study for the purpose of determining the safety and tolerability of LX214 ophthalmic solution in healthy volunteers and in patients with dry eye syndrome.

Completed8 enrollment criteria

Confirmatory Study of OPC-12759 Ophthalmic Suspension

Dry Eye Syndromes

The purpose of this study is to verify whether OPC-12759 ophthalmic suspension is effective compared with active control in dry eye patients.

Completed15 enrollment criteria

Acupuncture Treatment of Dry Eye

Keratoconjunctivitis SiccaXeropthalmia

The purpose of this study is to determine the safety and efficacy of acupuncture in the treatment of moderate to severe dry eye by replicating the study design of the previous protocol and to see the study through to its completion.

Completed9 enrollment criteria

Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Disease

The purpose of this trial is to compare the effectiveness and safety of INS365 Ophthalmic Solution with Placebo when applied topically in subjects with dry eye disease.

Completed8 enrollment criteria

Efficacy and Safety of a New Multi-dose Lubricant Eye Drop Concomitant With Restasis® (Cyclosporine...

Dry Eye

To evaluate the efficacy, safety and tolerability of a combination of Optive® Artificial Tears with Restasis®.The primary hypothesis is that the Ocular Surface Disease Index (OSDI) score and symptoms will be the same or lower than baseline after treatment in these patients. The patients will tolerate the combination of Restasis® and Optive® with a low incidence of clinical adverse events.

Completed7 enrollment criteria

Feasibility of IPL for Reducing Dry Eye Symptoms Caused by MGD

Dry Eye Syndromes

The purpose of this study is to evaluate if, in patients with meibomian gland dysfunction (MGD), treatment with the Lumenis M22 Intense Pulsed Light (IPL) system causes a reduction in dry eye symptoms post-treatment, compared to pre-treatment.

Completed36 enrollment criteria
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