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Active clinical trials for "Keratoconjunctivitis Sicca"

Results 711-720 of 779

Prospective Health Assessment of Cataract Patients' Ocular Surface

Dry Eye

This study will determine the incidence and severity of dry eye in patients undergoing cataract surgery as determined by grade on the International Task Force (ITF) scale.

Completed8 enrollment criteria

Dry Eye Under China's Dynamic COVID-zero Strategy

Dry Eye Symptoms

To compare the prevalence of dry eye symptoms and to investigate the association of the risk factors with the dry eye symptomatology among university students in the epidemic and non-epidemic areas of China under the COVID-zero strategy.

Completed6 enrollment criteria

Dry Eye Symptoms and Quality of Life

Dry Eyes

Dry eye syndrome is a very common condition with multiple etiologies that includes systemic and ocular disease that causes reduction in the production of tears, as well as increase in tears evaporation. As a result of the various etiologies and large variability of dry eye's clinical sign, it has been a challenge for practitioners to have a consistent system to classify dry eyes and to have an appropriate and accurate measurement to quantify the severity of dry eyes and its impact on patients' quality of life.6 To date, no study which evaluates the extent of questionnaires correlates with changes in quality of life. With this cross sectional interview study, we aim to determine the efficacy of the questionnaires as a practical tool in our future clinical trials at our center.

Completed4 enrollment criteria

A Randomized, Parallel-Group Comparison Study of Topical Corticosteroids in Dry Eye Patients With...

Dry Eye SyndromesSjögren Syndrome

The purpose of this study is to evaluate the effectiveness of fluorometholone combined with sodium hyaluronate eye drops in the treatment of Sjögren syndrome.

Completed7 enrollment criteria

Effect of Controlled Adverse Environment (CAE) on Tear Film Stability

Keratoconjunctivitis Sicca

The purpose of this study is to evaluate the effect of the controlled adverse environment (CAE) on Mean Break-Up Area in subjects diagnosed with Dry Eye Syndrome.

Completed10 enrollment criteria

Comparison of Ocular Surface Features in Patients With Diabetes and Dry Eye Syndrome

Dry Eye SyndromeDiabetes Mellitus Type 2

The study aims to compare the differences of ocular surface features in controls and patients with diabetes and dry eye syndrome, to thoroughly evaluate the ocular surface health of diabetics, and to find out the relationship between dry eye syndrome and diabetes

Completed11 enrollment criteria

Efficacy and Safety of Hydrolysed Red Ginseng Extract on Dry Eye

Dry Eye

This study was conducted to investigate the effects of daily supplementation of Hydrolysed Red Ginseng Extract extract on dry eye.

Unknown status20 enrollment criteria

Symptom Response in Normal and Dry Eye Patients Secondary to Application of a Menthol-Containing...

Dry Eye

The purpose of the study is to analyze the sensation to eye drops containing menthol in people with healthy eyes and in people with dry eyes. This study also examines the temperature of your eye using an Infrared Camera.

Completed17 enrollment criteria

Clinical Evaluation of the Causes of Contact Lens Related Dry Eye

Contact Lens Related Dry Eye

The purpose of this study was to clinically evaluate the potential causes of contact lens-related dry eye.

Completed13 enrollment criteria

CXCL9, CXCL10, CXCL11, and CXCR3 in Dry Eye Syndrome

Dry Eye Syndrome

The aim of this study is to investigate the expression of CXCL9, CXCL10, CXCL11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome. Thirty-three patients with dry eye (16 Sjögren's syndrome and 17 non-Sjögren's syndrome patients) and 15 control subjects were recruited. The concentrations of CXCL9, CXCL10, and CXCL11 in tears were measured using enzyme-linked immunosorbent assay. The correlation between chemokine levels and tear film and ocular surface parameters was analyzed. Expression of CXCL9, CXCL10, CXCL11, and CXCR3 in the conjunctiva was evaluated using immunohistochemistry. Flow cytometry was performed to count CXCR3+ cells and CXCR3+CD4+ cells in the conjunctiva.

Completed7 enrollment criteria
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