Efficacy and Tolerance of Nova22007 Versus Vehicle in Patients With Vernal Keratoconjunctivitis...
ConjunctivitisVernalThe primary objective of this study is: To assess the efficacy of Nova22007, a cyclosporine A (CsA), 0.05% and 0.1% versus vehicle in patients with vernal keratoconjunctivitis (VKC) after a 4-week treatment period. The secondary objectives of this study are: To compare the safety and ocular tolerance of Nova22007 0.05% and 0.1%; To assess the long term safety and ocular tolerance of Nova22007 0.05% and 0.1%; and To assess the decrease in frequency of concomitant artificial tears use.
Evaluation of Efficacy and Safety of an Anti-Allergy Drug With a Contact Lens in the Treatment of...
Allergic ConjunctivitisThe purpose of this study is to evaluate the efficacy and safety of an anti-allergy drug with a contact lens compared to placebo in preventing ocular itching associated with allergic conjunctivitis
Effect of Olopatadine on Allergic Tear Mediators
Allergic ConjunctivitisThe purpose of the research is to determine which inflammatory substances are involved in causing allergic symptoms in the eye. Allergic conjunctivitis is a common problem with symptoms of temporary redness, itching, tearing, and swelling of the eyes. Substances released by cells in the affected tissues cause allergic reactions in the eye and elsewhere in the body.
Standardization of Chortoglyphus Arcuatus Allergenic Extract. Determination of Biological Activity...
RhinitisAllergic3 moreThe main purpose of the trial is to prove the therapeutic value of the product and enable an effective and safe dosage schedule to be recommended
Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers
Allergic ConjunctivitisThe purpose of this study is to evaluate the safety of a novel contact lens in healthy normal volunteers
Clinical Validation Study in Allergic Conjunctivitis to Birch Pollen During Allergen Challenge in...
Allergic ConjunctivitisThis is a single center open study designed to determine the concentration of airborne birch pollen inducing an allergic conjunctivitis response in individuals allergic to birch pollen, during allergen exposures in the Alyatec environmental exposure chamber (EEC).
Evaluation of Subcutaneous Immunotherapy Towards Pollen in Children
RhinitisAllergic3 moreThe objective is to prospectively explore associations between immunological parameters in blood and clinical effect of subcutaneous immunotherapy (SCIT) in children with severe allergy towards pollen. Half of the children will receive SCIT while the other half will start SCIT after the study is finished. Clinical evaluations of symptoms and an immunological survey will be performed before start of SCIT and after one year of treatment. Some of the immunological parameters will also be checked after 6 months of treatment
A Study of AK002 in Patients With Atopic Keratoconjunctivitis, Vernal Keratoconjunctivitis, and...
Atopic KeratoconjunctivitisVernal Keratoconjunctivitis1 moreThis is a Phase 1b, open-label, study to assess the effects of AK002, given as monthly intravenous infusion for 6 doses at up to 3 mg/kg.
Safety and Comfort of AL-4943A Ophthalmic Solution
Allergic ConjunctivitisThe purpose of this study is to assess the ocular comfort and safety of olopatadine hydrochloride opthalmic solution. 0.7%.
Study of DE-114 Ophthalmic Solution in Patients With Allergic Conjunctivitis
Allergic ConjunctivitisThe purpose of the study is to demonstrate safety and efficacy of DE-114 ophthalmic solution compared to its Placebo and Olopatadine hydrochloride 0.1% ophthalmic solution in patients with allergic conjunctivitis.