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Active clinical trials for "Conjunctivitis, Allergic"

Results 81-90 of 209

A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic...

Allergic Conjunctivitis

A Multi-Center, Double-Masked, Randomized, Parallel-Group, Vehicle-Controlled, Methodology Development Environmental Clinical Trial with Reproxalap Ophthalmic Solutions (0.25% and 0.5%) in Subjects with Seasonal Allergic Conjunctivitis.

Completed9 enrollment criteria

Probiotic Chewables in Allergic Rhinoconjunctivitis Patients

Allergic Rhinoconjunctivitis

With this double- blind, randomised, placebo-controlled study, the investigators want to investigate the influence of a chewable with the probiotic strain Lacticaseibacillus rhamnosus GG on the symptoms and immunological markers of allergic rhinoconjunctivitis (AR). In addition, the investigators aim to study the influence of this probiotic chewable on the microbiome of the upper respiratory tract after administration in adults with AR. The bacterial and cytokine profiles in the naso- and oropharynx will be monitored before, during and after the treatment.

Completed17 enrollment criteria

A Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Allergic Conjunctivitis...

Allergic Conjunctivitis

The objective of the study is to evaluate the efficacy and safety of OTX-DP as a dexamethasone ophthalmic insert when placed in the canaliculus of the eyelid for the treatment of the signs and symptoms of allergic conjunctivitis.

Completed7 enrollment criteria

Subcutaneous Immunotherapy in Patients Sensitized to Dermatophagoides Pteronyssinus (DPT)

Allergic Rhinoconjunctivitis

Based on EMA (European Medicines Agency) new guidelines on the clinical development of products for immunotherapy for the treatment of allergic diseases the aim of this study was to assess safety and tolerability of 3 different subcutaneous immunotherapy dose escalations in patients allergic to Dermatophagoides pteronyssinus.

Completed25 enrollment criteria

Safety Study of Ophthalmic Solution in Healthy, Normal Volunteers

Healthy Volunteers Eligible for Study; Drug Being Developed for Allergic Conjunctivitis

The purpose of this study is to evaluate the safety of R89674 0.25% ophthalmic solution in healthy normal volunteers

Completed3 enrollment criteria

PURETHAL Grasses Rush Study

Allergic RhinitisAllergic Rhinoconjunctivitis

This study investigates the safety of two up-dosing regimen. The safety of PURETHAL Grasses will be evaluated in a rush regimen (maximum dose reached in 3 injections during 2 weeks) compared to the conventional regimen (maximum dose reached in 6 injections during 5 weeks). The primary parameter will be the proportion of patients who experience systemic reactions > grade I within 24 hours after injection or who need more than 2 additional injections during the up-dosing phase until the maintenance dose has been reached. It is expected that up-dosing PURETHAL Grasses according to the rush regimen is as safe as using the conventional regimen.

Completed27 enrollment criteria

Safety and Tolerance Study of Grass Pollen-derived Peptides to Treat Allergic Rhinitis

Seasonal Allergic Rhinoconjunctivitis

The purpose of this study is to determine whether the oral administration of grass pollen peptides to treat allergic rhinitis is safe and well tolerated.

Completed29 enrollment criteria

Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Acute...

Allergic Conjunctivitis

The purpose of this study is to establish the safety and efficacy of ketotifen/naphazoline ophthalmic solution compared to vehicle and its individual components in alleviating the signs and symptoms of conjunctival allergen challenge (CAC)-induced allergic conjunctivitis.

Completed7 enrollment criteria

Evaluation of Efficacy of Coadministration of FOV1101-00 and Prednisolone Acetate in Patients With...

Allergic Conjunctivitis

This is a phase 2 study that will consist of 3 visits during a 3 week period conducted at up to 5 sites. The purpose of this study is to determine how effective the combination of Pred Mild® and FOV1101-00 is compared to either Pred Forte® alone or to vehicle alone in the prevention of eye allergies. Study subjects will be randomized to one of the following: FOV1101-00 concentration 1 and Pred Mild® FOV1101-00 concentration 2 and Pred Mild® Vehicle of FOV1101-00 and Pred Forte® Vehicle of FOV1101-00 and Vehicle of FOV1101-00

Completed2 enrollment criteria

Cyclosporin A Eye Drop Treatment in Vernal Keratoconjunctivitis

Vernal Keratoconjunctivitis

This interventional study aims to evaluate the efficacy of Cyclosporine eye drop treatment in preventing relapses of Vernal Keratoconjunctivitis (VKC) and in treating the acute phases of the disease.

Completed7 enrollment criteria
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