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Active clinical trials for "Keratosis, Actinic"

Results 141-150 of 331

Efficacy and Safety Study of LAS41007 in the Treatment of Actinic Keratosis

Actinic Keratosis

The aim of this study is to determine the efficacy, safety and tolerability of either a once or twice daily topical application of LAS41007 compared to a twice daily application of LAS106521 in the treatment of actinic keratosis.

Completed12 enrollment criteria

A Photodynamic Therapy for Treatment of Actinic Keratoses

Actinic Keratoses

The purpose of this study is to compare the efficacy of photodynamic therapy with 5-aminolevulinic acid and intense pulsed light vs absence of treatment for actinic keratoses.

Completed13 enrollment criteria

Pharmacokinetic Study to Evaluate the Extent of Systemic Absorption of PEP005

Actinic Keratoses

The purpose of this study is to determine the extent of systemic absorption of PEP005 when applied topically for the treatment of actinic keratoses.

Completed4 enrollment criteria

A Study to Examine the Safety and Toleration of PEP005 Topical Gel in Patients With Actinic Keratoses...

Actinic Keratosis

The purpose of this study is to examine the safety and toleration of PEP005 Topical Gel, administered on an actinic keratosis (AK) treatment area on the top of a hand.

Completed5 enrollment criteria

Safety and Effectiveness Study of Imiquimod Creams for the Treatment of Actinic Keratoses (AKs)...

Actinic Keratosis

The purpose of this study is to determine whether imiquimod creams are effective in treating Actinic Keratoses when applied to the face or balding scalp. Actinic keratosis (AK) is a skin condition that shows up on skin routinely exposed to the sun, such as the face, scalp, shoulders, chest, back, arms, and hands. The active ingredient contained in the study cream for this study is the same as that of the approved product Aldara, which has shown to be safe and effective for the treatment of AKs.

Completed8 enrollment criteria

A Multi-center Study to Evaluate the Safety and Efficacy of PEP005 (Ingenol Mebutate) Gel, When...

Actinic Keratosis

The open label study is designed to assess the safety and efficacy of 0.05% PEP005 Gel when applied to an area of skin containing 4-8 AK lesions on non-head locations.

Completed7 enrollment criteria

Photodynamic Therapy With PD P 506 A Compared With Placebo-PDT for the Treatment of AK

Actinic Keratosis

The aim of this study is to investigate whether PD P 506 A-PDT is effective in treating mild to moderate AK lesions located on the head.

Completed22 enrollment criteria

An Open-Label 18-Month Safety Study of Fluorouracil Cream 0.5% for the Treatment of Actinic Keratoses...

Actinic Keratoses

This study is being undertaken to: 1. assess the safety of fluorouracil cream for the treatment of actinic keratoses ("AKs") on other common skin surface areas (e.g., posterior scalp, ears, neck, lips, arms and hands); 2. collect additional post-treatment safety data on fluorouracil cream applied to the face (including anterior scalp, if applicable); 3. assess the incidence of recurrence of AKs on the face; and 4. assess the need for re-treatment with fluorouracil cream to the face.

Completed14 enrollment criteria

Eflornithine With or Without Triamcinolone in Preventing Nonmelanoma Skin Cancer in Patients With...

Non-melanomatous Skin CancerPrecancerous/Nonmalignant Condition

RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. Eflornithine with or without triamcinolone may be effective in preventing nonmelanoma skin cancer. PURPOSE: Randomized phase II trial to compare the effectiveness of eflornithine with or without triamcinolone in preventing nonmelanoma skin cancer in patients who have actinic keratosis.

Completed3 enrollment criteria

Study to Evaluate the Safety of BF-200 ALA (Ameluz®) for Photodynamic Therapy (PDT) in the Treatment...

Actinic Keratoses

The aim of this study is to assess the pharmacokinetics (PK) of the parent drug 5-aminolevulinic acid (ALA) and its active metabolite protoporphyrin IX (PpIX) during photodynamic therapy with 3 tubes of BF-200 ALA 10% gel (Ameluz®) in combination with the BF-RhodoLED® lamp in the systemic circulation of diseased individuals presenting with actinic keratosis (AK) on the face/scalp or in the periphery (neck/trunk/extremities) along with subjects' safety/tolerability during and after treatment.

Completed51 enrollment criteria
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