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Active clinical trials for "Keratosis"

Results 61-70 of 350

Effectiveness of Saline Water and Lidocaine Injections for the Treatment of Intractable Plantar...

Intractable Plantar Keratoma

An intractable plantar keratoma (IPK) is a conical thickening of the epidermis' stratum corneum and a common cause of foot pain which can have a significant, detrimental impact on the mobility, quality of life and independence of individuals. Conservative treatments are currently offered to patients with IPK, but they are unsatisfactory since they do not offer a sufficient or permanent reduction of symptoms. The purpose of this study was the evaluation of the feasibility, safety and effectiveness of innovative treatments for intractable plantar keratoma (IPK)

Completed8 enrollment criteria

Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of...

Actinic Keratoses

Fluorouracil is recommended for the topical treatment of multiple actinic or solar keratoses. In the 5% strength, it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites.

Completed16 enrollment criteria

A Study to Evaluate the Safety and Tolerability of Tirbanibulin Ointment 1% in Adult Participants...

KeratosisActinic

The purpose of the study is to evaluate the safety, tolerability and treatment effect of tirbanibulin ointment 1% when applied to a field of approximately 100 cm^2 on the face or balding scalp.

Completed13 enrollment criteria

Actinic Keratosis Study

Actinic Keratosis

The main purpose of this study is to determine the effectiveness of a new combination therapy for actinic keratosis. This study investigates a new indication for an FDA-approved topical medication, calcipotriol, for treatment of actinic keratosis, including how well it works and how safe it is when used in combination with the standard of care medication (5-fluorouracil) for the skin condition.

Completed8 enrollment criteria

A Study Comparing Diclofenac Sodium Gel 3% to Solaraze® (Diclofenac Sodium) Gel 3% in the Treatment...

Actinic Keratosis

To compare the relative efficacy and safety of the test formulation diclofenac sodium gel 3% (Actavis) to the marketed formulation Solaraze® (diclofenac sodium) Gel 3% (Fougera Pharms) in the treatment of the actinic keratosis

Completed25 enrollment criteria

Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days...

Actinic Keratosis

Part 1: To identify Maximum Tolerated Dose (MTD) levels of LEO 43204 after once daily treatment for two consecutive days Part 2: To evaluate the efficacy of LEO 43204 in two doses after once daily treatment for two consecutive days compared to vehicle

Completed9 enrollment criteria

Protocols for Painless Photodynamic Therapy (PDT) of Actinic Keratoses

Actinic Keratosis

This study is being done to compare a new, continuous illumination regimen of ALA-PDT (Aminolevulinate-Photodynamic Therapy) to a conventional regimen for treatment of actinic keratoses. The hypothesis is that the continuous illumination approach will be less painful, but equally efficacious, as the old regimen.

Completed5 enrollment criteria

Safety and Tolerability of Different Concentrations of an Ingenol Derivative Field Therapy in the...

Actinic Keratosis

The purpose of this study is to determine if the new ingenol derivative gels are as safe as and as well tolerated as ingenol mebutate gel when applied to AK lesions on the forearm for two consecutive days.

Completed12 enrollment criteria

Effect of Nigella Sativa in the Treatment of Palmer Arsenical Keratosis

Arsenical Keratosis

Daily intake of Nigella sativa for 12 weeks is effective in the treatment of palmer arsenical keratosis

Completed12 enrollment criteria

Safety and Dose Finding Study of New Vehicle Formulations Containing Ingenol Mebutate to Treat Actinic...

Actinic Keratosis

The purpose of this study is to determine if the new vehicle formulations containing ingenol mebutate are as safe and effective as Picato® gel 0.05% (it's current vehicle formulation) when applied to AK lesions on the forearm for two consecutive days.

Completed16 enrollment criteria
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