search

Active clinical trials for "Renal Insufficiency"

Results 441-450 of 1903

Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Receiving...

AnemiaIron-Deficiency2 more

This study compares the effect of Ferrlecit® (a form of intravenous iron) to ferrous sulfate (a form of oral iron) in treating anemia and iron deficiency in chronic kidney disease patients who are receiving erythropoietic agents, such as Procrit® and Aranesp®.

Completed7 enrollment criteria

Acetylcysteine in the Prevention of Renal Failure After Bypass Surgery

Kidney Failure

The purpose of this study is to determine if Acetylcysteine is effective in preventing renal failure associated with cardiac surgery

Completed5 enrollment criteria

Renal Function Evaluation After Reduction of Cyclosporine A Dose in Renal Transplant Patients

Kidney TransplantationPrimary Prevention1 more

The purpose of the study is to show the efficacy of reduction of cyclosporine A exposure measured by the area under the curve by Bayesian estimator on the primary prevention of degradation of the renal function in renal transplant recipients

Completed13 enrollment criteria

Efficacy and Safety of Lanthanum Carbonate and Sevelamer Hydrochloride in Patients Receiving Haemodialysis...

Kidney FailureChronic

The purpose of this study is to assess phosphate reduction and control in patients with End Stage Renal Disease treated with either lanthanum carbonate or sevelamer hydrochloride

Completed6 enrollment criteria

Valsartan in Cardiovascular Disease With Renal Dysfunction (The V-CARD) Study

Hypertension

The purpose of this study is to investigate if an angiotensin II receptor blocker, valsartan 160 mg/day is more effective to reduce the incidence of cardiovascular events as compared to 40 mg/day in patients with moderate renal dysfunction.

Terminated11 enrollment criteria

Safety and Pharmacokinetics of Single Intravenous Doses of Peginesatide in Healthy Volunteers

AnemiaChronic Kidney Disease2 more

The purpose of this study is to evaluate the safety, pharmacokinetics (PK), and minimum pharmacologically active dose of peginesatide in Healthy Volunteers.

Completed4 enrollment criteria

Pharmacokinetics/Pharmacodynamics of Argatroban Injection in End-Stage Renal Disease Patients Undergoing...

Kidney FailureChronic2 more

The primary goals of this investigation are to provide guidance on how to dose Argatroban in patients undergoing hemodialysis and to assess the safety and tolerability of Argatroban in hemodialysis patients. The secondary goal of the study will be to assess the adequacy of anticoagulation during hemodialysis.

Completed20 enrollment criteria

Resistance Training and Diet in Patients With Chronic Renal Failure

Kidney FailureChronic

This study will examine the effects of long-term adherence to a low protein diet (LPD) of 0.6 g/kg-1/d-1 with and without progressive resistance exercise training in patients with impaired renal function on body composition, renal function (glomerular filtration rate), nitrogen balance, muscle strength and size, and functional capacity. The hypothesis is that adherence to a LPD will result in a reduction in skeletal muscle mass and reduced strength and functional capacity while those patients who adhere to the LPD and exercise will demonstrate a similar preservation of renal function but will have greater fat free mass, muscle mass and strength. The intervention trial will last 18 months in which patients with moderate renal failure will be randomly assigned to one of 4 interventions: standard care, standard care + exercise, LPD, and LPD with exercise. In this way the independent and combined effects of diet and exercise on the progression of renal disease and body composition will be monitored. This study will have important implications for the treatment of patients with chronic renal failure. New strategies of combining exercise with recommendations of a low protein diet may slow the progression of renal disease and improve strength and functional capacity in these at-risk patients.

Completed3 enrollment criteria

Phase I Study of Alpha-Melanocyte Stimulating Hormone in Patients With Acute Renal Failure

Acute Renal Failure

OBJECTIVES: I. Determine the maximum tolerated dose and safety of alpha-melanocyte stimulating hormone (alpha-MSH) in patients with acute renal failure. II. Determine the safety and pharmacokinetics of alpha-MSH in patients at high risk of acute renal failure after renal transplantation. III. Determine the safety and pharmacokinetics of alpha-MSH in patients with established ischemic acute renal failure. IV. Determine the effect of alpha-MSH on interleukin-10 pharmacokinetics.

Completed9 enrollment criteria

A Study of Molidustat for Correction of Renal Anemia in Non-dialysis Subjects

AnemiaRenal Insufficiency1 more

The purpose of this study is to evaluate the efficacy and safety of molidustat in non-dialysis subjects with renal anemia who are not treated with Erythropoiesis-Stimulating Agents (ESAs).

Completed11 enrollment criteria
1...444546...191

Need Help? Contact our team!


We'll reach out to this number within 24 hrs