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Active clinical trials for "Alzheimer Disease"

Results 181-190 of 2939

Music Therapy Experiences in Patients With Mild Cognitive Impairment (MCI) and Alzheimer's Disease...

Alzheimer's DiseaseMild Cognitive Impairment

This study compares different music therapy (MT) experiences and their impact on memory and language in patients with Alzheimer's disease and Mild Cognitive Impairment. The 12-month study will assess the role of common experiences involving familiar music and other pleasant events (blinded control) to benefit cognition and measure the quality of life for people with Alzheimer's disease and Mild Cognitive Impairment. Following screening, all participants will meet with a licensed music therapist at the first study visit. Thereafter, each group will have an individualized schedule of follow-up telephone calls and visits. Screening for the study and participation in the study intervention can be completed in-person or from your home, if you do not live in the area.

Recruiting13 enrollment criteria

Improvement Effect of Lacosamide and Levetiracetam on Cognitive in Alzheimer's Disease Patients...

Alzheimer Disease 3Epilepsy

Participants will perform Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Clinical Dementia Rating (CDR), Alzheimer's disease assessment scale-cognitive section (ADAS-Cog), Hamilton Anxiety Scale (HAMA) and Hamilton Depression Rating Scale (HAMD) evaluation. The patients will be randomly divided into two groups, treated with lacosamide and levetiracetam respectively, and maintained for 6 months. Researchers will compare the lacosamide group with the levetiracetam group to see if the improvement of cognitive function in the two groups.

Recruiting7 enrollment criteria

Long Term, Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation...

Agitation in Patients With Dementia of the Alzheimer's Type

This is an extension study of the Phase 3 Studies 15-AVP-786-301, 15-AVP-786-302, and 17-AVP-786-305, which also allows participants from the Phase 2 Study 12-AVR-131 to be included.

Recruiting10 enrollment criteria

Virtual Reality Cognitive Therapy for Alzheimer's Disease

Alzheimer Disease

To evaluate the usability, feasibility, and acceptability of VRCT iteratively on 36 AD/ADRD individuals with mild to moderate CI.

Recruiting7 enrollment criteria

Creatine to Augment Bioenergetics in Alzheimer's

Alzheimer's Disease

By doing this study, researchers hope to see if creatine monohydrate is a helpful treatment for people with Alzheimer's disease.

Recruiting14 enrollment criteria

Self-Care for Dementia Caregivers

AgingMental Disorder8 more

The Self-Care for Dementia Caregivers research study is a pilot randomized control trial (RCT) to develop and evaluate the feasibility of a behavioral intervention that uses technology and motivational health coaching to optimize caregivers' sleep, exercise, and social activities. Caregivers of family members with Alzheimer's Disease (AD) and AD-related dementias often experience disruptions of their biological or behavioral time cues, placing them at higher risk for adverse health outcomes. The investigators hypothesize that targeting the stability of sleep, exercise, and social activities will improve stability of the biological clock, improve caregiver health and wellbeing, and improve their ability to provide care.

Recruiting9 enrollment criteria

Stimulation of Cingulo-opercular Alertness Network

Lewy Body DiseaseLewy Body Variant of Alzheimer Disease1 more

Fluctuations in alertness are very common in persons with Lewy body dementias and are a major source of disability. Changes in a chemical messenger molecule called acetylcholine within certain brain regions may play a role in these fluctuations. We propose to test this hypothesis and also determine whether a non-invasive way of stimulating affected brain regions may be of relevance for future management of these fluctuations.

Recruiting14 enrollment criteria

The Interactive Physical and Cognitive Exercise System (v3) for Mild Cognitive Impairment (MCI)...

MCIMild Cognitive Impairment2 more

The primary purpose of this study is to attempt to replicate and extend promising pilot findings regarding the cognitive benefits of in-home neuro-exergaming with iPACES (interactive Physical and Cognitive Exercise System v3) for persons with mild cognitive impairment (MCI). Participants will include persons with MCI and their co-residing partner who both exercise at home 3-5 times per week for at least 6 months and are followed through one year. All participation is "remote" (completed at home), with all equipment (pedaler, tablet, etc.) supplied directly to the home, and with all study measures completed via videoconference and mail.

Recruiting19 enrollment criteria

A Pivotal Study of LIPUS-Brain in Patients With Early Alzheimer's Disease

Alzheimer DiseaseEarly Onset

This study is a multicenter, randomized, double-blinded, placebo-controlled Phase 3 study comparing LIPUS-Brain transcranial low-intensity pulsed-wave ultrasound device to placebo in patients with Early Alzheimer's Disease. The primary objective of the study is to assess changes in ADAS-J-cog-14 scores from baseline to 72 weeks.

Recruiting29 enrollment criteria

Telerehabilitation Alzheimer's Disease Feasibility (TADF)

Alzheimer DiseaseHealthy Aging

This is a pilot RCT with equal arms: experimental arm and (wait list) control arm. All participants will be in the early stage of Alzheimer's disease and on stable medication. They will all continue with this medication for their 6 months participation. Experimental group will add weekly training on the experimental device, 5 days a week for 8 weeks. Training will involve therapeutic games aimed primarily at the memory cognitive domain. All participants will receive weekly calls from clinical coordinator and report on medication and overall health. Caregivers will also be enrolled so they support the trials.

Recruiting23 enrollment criteria
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