Efficacy of Nutritional Supplement VIUSID/ALZER in Patients With Parkinson's Disease
Parkinson's DiseaseThe purpose of the study is to evaluate whether Viusid/Alzer Nutritional supplements, could improve the progression disease, in patients with Parkinson's Disease (PD).
Methylphenidate for the Treatment of Gait Impairment in Parkinson's Disease
Parkinson's DiseaseGait ImpairmentThe purpose of this research study is to examine whether Methylphenidate (MPD) can result in improvement of gait (walking) in a population of Parkinson's Disease (PD) patients whose main disability is freezing of gait. MPD (Ritalin®) is a drug which can excite or stimulate certain systems of the body that control motor function. This drug is FDA approved for the treatment of attention hyperactivity disorder, a condition unrelated to PD. The researchers hypothesize that daily treatment with a tolerable daily oral dose of MPD will improve gait velocity, stride length, cadence, and decrease freezing of gait, 3 months from treatment initiation in patients with moderately advanced PD, whose gait impairment is an important source of disability despite optimized antiparkinsonian treatment.
A Single-Dose, 2-Period, 2-Treatment, 2-Way Crossover Bioequivalency Study of Ropinirole 0.25 mg...
Parkinson's DiseaseRestless Leg SyndromeThe objective of this study was to assess the single dose bioequivalence of Roxane's Ropinirole tablets,0.25 mg, to ReQuip Tablets, 0.25 mg (GlaxoSmithKline) under fed conditions using a single dose, randomized, 2-treatment, 2-period, 2-sequence cross-over design.
Monitoring Movement Disorder Symptoms With a Mobile Medical App on Off-the-shelf Consumer Mobile...
Parkinson DiseaseThe purpose of this study is to evaluate whether New Touch Digital (NTD) NeuroRPM software installed on wearable devices can objectively measure and track symptoms in patients with Parkinson's disease.
Preventing Falls and Participation Restrictions in Neurological Diseases
Multiple SclerosisParkinson Disease1 moreA randomized open clinical trial to assess the added value of a comprehensive rehabilitation program on fall prevention and improve participation and activities of daily living. Baseline assessment, 6-month experimental intervention (experimental group) vs. usual rehabilitation programs and assessment at end of treatment and six months after treatment will be performed.
Prism Adaptation Treatment of Parkinson's Disease
ParkinsonSubjects diagnosed with Idiopathic Parkinson's Disease, between ages of 40-85 inclusive, who have been referred for gait training. Since there can be subtle differences in the brain organization of left- and right-handed people that may influence some of the measurements, right handed participants are preferred. However, a left handed participant may be considered. Participants will be randomly assigned to one of two groups to undergo two weeks of twice-daily sessions. Group A receiving goggles fitted with lenses that distort vision and Group B patients receiving sham goggles
Pharmacokinetic Study in Healthy Males
Parkinson's DiseaseThe purpose of this study is to investigate the pharmacokinetics of levodopa, carbidopa, 3-OMD and ODM-104 after repeated doses of 3 levodopa formulations given in combination with carbidopa and ODM-104.
Effect of Paracetamol on Opicapone Pharmacokinetics in Healthy Volunteers
Parkinson's DiseaseSingle-centre, open-label, randomised, two-way cross-over study consisting of 2 periods separated by a washout period of 14 days or more.
Resistance Versus Balance Training in Parkinson's Disease
Parkinson's DiseaseComparison of resistance training versus balance training to improve postural control in patients with Parkinson's Disease
Study to Evaluate the Efficacy of Rotigotine on Parkinson's Disease-Associated Pain
Advanced Idiopathic Parkinson's DiseaseThis trial is being conducted to compare the impact of Rotigotine and Placebo on Chronic Pain associated with Parkinson's Disease among patients with advanced stages of the disease.