Study of the Effectiveness of Osteopathic Manipulative Treatment in Pregnant Women
Low Back PainMusculoskeletal Diseases1 moreThe purpose of this study is to determine whether osteopathic manipulative treatment (OMT): decreases pain and improves physical functioning in women during the third trimester of pregnancy decreases complications during obstetrical delivery improves quality of life in the post-partum period
Efficacy and Safety of Bicifadine in the Treatment of Chronic Low Back Pain
Chronic Low Back PainThe primary objectives of this placebo-controlled clinical trial are to evaluate the analgesic efficacy and safety of bicifadine 200 mg BID compared with placebo in patients with moderate to severe chronic low back pain. The secondary objectives are to evaluate the effect of bicifadine on function and general quality of life, to evaluate safety following discontinuation of bicifadine treatment and to investigate the population pharmacokinetics of bicifadine.
Treatment of Veterans With Chronic Low Back Pain
Low Back PainRecurrentThe purpose of this study is to assess the effectiveness of hypnosis in the treatment of chronic low back pain.
Imaging Study of Chronic Low Back Pain in Patients Taking Pain Medication
Low Back PainDuloxetine has recently been shown to be effective in reducing the pain in chronic pain patients. Duloxetine is known to exert a central mechanism, however the precise human brain structures responsible for mediating its pain-relieving properties are not known. We will use functional magnetic resonance imaging (FMRI) to investigate the neural and functional correlates of pain.
Acupuncture Analgesia in Relation to Psychiatric Comorbidity
Low Back PainIt is our hypothesis that patient's expectations concerning treatment outcome will be influenced by their psychiatric symptoms, and that this expectancy will have a strong influence on the efficacy of acupuncture treatment to suppress experimentally induced pain. We will conduct a study, monitoring expectations but not manipulating them, in a cohort of patients with chronic low back pain.
Study of the Insomnia in Patients With Low Back Pain
Primary InsomniaThe purpose of this study is to examine whether insomnia due to chronic low back pain can improve with use of eszopiclone.
Effectiveness of Adding Behavioral Therapy to Physical Therapy to Treat Low Back Pain
Low Back PainLow back pain is a very common problem and the most common cause of job-related disability. While some occurrences of low back pain disappear within a couple of days, other occurrences take much longer to resolve or lead to more serious conditions. The purpose of this study is to determine the effectiveness of two behavioral types of therapy in reducing future disability in people who are receiving physical therapy for low back pain and tend to fear and avoid pain.
Mindfulness Meditation for Chronic Low Back Pain in Older Adults
Low Back PainAmong mind-body therapies, there is evidence for an association between pain reduction and mindfulness meditation. Mindfulness meditation provides a potentially safe, effective, nonpharmacologic, noninvasive, simple method for pain relief and increased function that could be used for the frailest older adult. Additionally, mindfulness meditation addresses the multiple dimensions that are affected by chronic pain. The primary objective of this study is to determine the impact of an 8-week mindfulness-based stress reduction program on physical function and pain severity in community dwelling older adults with chronic low back pain. Using a randomized controlled experimental design, 80 community dwelling older adults ≥ age 65 with chronic low back pain will receive either (1) the MBSR program, or (2) an 8-week education program. Prior to initiating the program, immediately after the last program session, and 6 months later, the following parameters will be assessed: (1) pain severity, (2) disability/physical function, (3) objectively measured physical performance, (4) psychosocial function (including mood, self-efficacy, self-rated health, coping, stress, quality of life (QOL), mindfulness and pain-related fear), (5) sleep, (6) pain-related appetite reduction and, (7) time and frequency of meditation. All measures are self-report except for the physical performance measure.
Cognitive Interventions and Nutritional Supplementation for Patients With Long-lasting Back Pain...
Chronic Low Back PainCINS is a large multicentre study which aims to test out the effect of 4 different interventions, namely a brief cognitive intervention (BI), a more extensive cognitive behavioural intervention (CBT), and 2 different nutritional supplementations (seal oil and soy oil) in a population of chronic low back pain patients sicklisted for 2-10 months.
Duloxetine Versus Placebo in Chronic Low Back Pain
Back Pain Without RadiationThe primary purpose of your participation in this study is to help answer the following research question, and not to provide you treatment for your condition--Whether duloxetine once daily can help patients with Chronic Low Back Pain.