search

Active clinical trials for "Low Back Pain"

Results 1301-1310 of 2244

A Clinical Study of the GO-LIF® Approach for Lumbar Spinal Fixation

Lower Back Pain

The purpose of this study is to collect data regarding the safety and feasibility of the GO-LIF procedure for spinal fixation and stabilization, in conjunction with conventional approaches for interbody lumbar fusion. This is in order to allow for evidence-based comparison to pedicle-screw-based techniques as described in the literature.

Completed25 enrollment criteria

Study to Investigate the Safety, Tolerability and Pharmacokinetics of AZD1940

Low Back Pain

A Phase I, Multi-Centre, Randomised, Double-blind, Placebo-controlled Study to Investigate the Safety, Tolerability and Pharmacokinetics of AZD1940, Including an Interaction Study, After Administration of Oral Multiple Ascending Doses in Adult Subjects with Chronic Low Back Pain

Completed6 enrollment criteria

Topical Lidocaine Patch in Low Back Pain

Acute and Chronic Non-radicular LBP

Patients with acute or chronic Lower Back Pain (LBP) participated in a Phase IV clinical trial to assess the effectiveness of Lidoderm administered once daily (q24h) for 2 weeks in the treatment of acute and chronic LBP.

Completed21 enrollment criteria

A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic...

Postherpetic NeuralgiaDiabetic Neuropathy1 more

Patients with a diagnosis of postherpetic neuralgia (PHN), diabetic neuropathy (DN), or low back pain (LBP) who were currently receiving an analgesic regimen that contained gabapentin participated in a Phase IV clinical trial to assess the effectiveness of Lidoderm® administered once daily (q24h) after 14 day in the treatment of PHN, DN, or LBP in patients who had a partial response to a regimen containing gabapentin.

Completed10 enrollment criteria

An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503)...

PainOsteoarthritis1 more

The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Completed9 enrollment criteria

RN624 In Adult Patients With Chronic Low Back Pain

Low Back Pain

The primary objective of this study is to evaluate the analgesic efficacy of RN624 compared with placebo and compared with naproxen in the treatment of adult patients with chronic low back pain.

Completed10 enrollment criteria

Effect of Etoricoxib to Treat Chronic Low Back Pain (0663-042)

Recurrent Low Back Pain

Study the effect of etoricoxib 60 mg and 90 mg compared to placebo to treat chronic low back pain.

Completed10 enrollment criteria

Disc Prosthesis Versus Multidisciplinary Rehabilitation

Chronic Low Back PainDegenerative Disc Disease

Surgical methods offered to patients with chronic low back pain are controversial. In addition, new and expensive treatment methods like total disc replacemet (TDR) are a challenge for the health care services. At present, ongoing randomized studies in both Europe and USA are comparing TDR to fusion. However, to our knowledge, no randomized trials have compared TDR to non-surgical treatment. The aim of the present study is to evaluate the effect of a comprehensive and structured non-surgical treatment with TDR surgery in patients with chronic low back pain and localized degenerative disc changes. Main hypothesis: There is no difference in treatment effect between surgery with lumbar total disc prosthesis and a multidisciplinary rehabilitation program measured by Oswestry Disability Index after 1 and 2 years. Secondary hypothesis: There is no difference in cost - effectiveness between surgery with lumbar disc prosthesis and a multidisciplinary rehabilitation program after 1 and 2 years.

Completed17 enrollment criteria

Rehabilitation of Patients With Modic Changes in the Lumbar Spine

Low Back Pain

The purpose of this study is to compare patients with low back pain (LBP) and Modic Changes from The Backcenter Funen, Ringe: To compare the effect of two types of non-operative treatments: A. exercise and advice to be physically active B. restitution and advice not to overload the spine To investigate if the results of the treatment are influenced by gender, age, smoking, and physical load.

Completed11 enrollment criteria

The Right Intervention for the Right Patient

Low Back Pain

Complicated and expensive interventions are used to treat unspecific low back pain and the intervention is not always targeted the patients specific problems.It is therefore not surprising that a large fraction of unspecific low back pain patients do not respond very well to the usual biopsychosocial intervention. We would therefore like to identify the patients specific problems regarding the patients biomedical, psychological, and social needs.

Completed10 enrollment criteria
1...130131132...225

Need Help? Contact our team!


We'll reach out to this number within 24 hrs