Capnography Monitoring in Ventilated Children
ChildOnly12 moreEnd-tidal CO2 measurements in children will be assessed for their accuracy with arterial CO2 measurements.
Segmentation of Structural Abnormalities in Chronic Lung Diseases
Cystic FibrosisAsthma2 moreLung structural abnormalities are complex, time-consuming, and may lack reproducibility to evaluate visually on CT scans. The study's aim is to perform automated recognition of structural abnormalities in CT scans of patients with chronic lung diseases by using dedicated software.
Remote Assessment of Lung Disease and Impact on Physical and Mental Health
Chronic Obstructive Pulmonary DiseaseInterstitial Lung Disease1 moreThis cohort study aims to use the open-source RADAR-base mHealth platform to collect and analyze datasets associated with lung disease. This will include continuous data collected from wearable devices (e.g. heart rate, oxygen saturation, respiratory rate), including pulse oximeters, spirometer, mobile phones, digital tests, and smart phone symptom questionnaires.
Post COVID-19 Interstitial Lung Disease: A Study of Genetic and Environmental Interactions
Pulmonary FibrosisCOVID-19 PneumoniaThis study aims to understand why some people who have had COVID-19 develop scarring of the lungs and why some people recover more quickly than others.
A Study to Test Whether Nintedanib Influences the Components of Birth-control Pills in Women With...
SclerodermaSystemicThe main objective is to assess the potential influence of continuous intake of nintedanib on the systemic exposure of ethinylestradiol and levonorgestrel when administered in combination.
Post-marketing Surveillance of Ofev Capsules in Chronic Fibrosing Interstitial Lung Diseases With...
Lung DiseasesInterstitialThe primary objective is to evaluate the incidence of adverse drug reactions (focus on hepatic function disorders) of Ofev Capsules under the real world setting in patients with Chronic fibrosing Interstitial Lung Diseases with a progressive phenotype (PF-ILD).
Interstitial Lung Diseases in the Veterans Administration
Interstitial Lung DiseaseThe primary objective of this research project is to describe the characteristics, diagnosis, management, and outcomes of patients with Interstitial Lung Disease (ILD) who received care at the Veteran's Administration Veterans Integrated Service Network (VISN) 6 Mid-Atlantic Health Care Network (VISN6) (includes North Carolina, Virginia and West Virginia) for up to 5 years.
Effects of Automated Oxygen Titration Alone or With High Flow Nasal Therapy on Dyspnea and Exercise...
DyspneaLung Diseases4 moreThe main purpose of this study is to evaluate the effects of automated oxygen administration (FreeO2 system) alone or with high-flow oxygen on dyspnea and exercise tolerance in people with desaturating chronic lung disease compared to fixed oxygen therapy.
Evaluation of the Diagnostic Utility of INS316 in Patients With Interstitial Lung Diseases (01-701)...
Interstitial Lung DiseaseThe objective of the present work is to explore and compare the diagnostic quality of sputum specimens obtained by BAL, induction with hypertonic saline (3%), and induction with INS316 in patients diagnosed with interstitial lung diseases.
Effect of Sildenafil on Diffusion Capacity in Patients With PH and Parenchymal Lung Disease
Diffuse Parenchymal Lung DiseasePulmonary HypertensionThe purpose of this study was to investigate the acute effects of sildenafil on diffusion capacity, a commonly performed pulmonary function test, which is used to assess the lungs' gas exchange capability. This study does not assess safety or efficacy of the drug. The study does not have clinical end points. The variables studied are diffusion capacity and 6 minute walk after a single dose of sildenafil. This study has been completed.