search

Active clinical trials for "Lung Diseases"

Results 3221-3230 of 3242

The Gut-lung Axis in Chronic Obstructive Pulmonary Disease

Pulmonary DiseaseChronic Obstructive4 more

Patients with chronic obstructive pulmonary disease (COPD) are 2-3 times more likely to occur together with chronic gastrointestinal tract (GIT) diseases, such as inflammatory bowel disease (IBD) or irritable bowel syndrome (IBS). Similarly, despite many patients have no history of acute or chronic respiratory disease, up to 50% of IBD patients and 33% of IBS patients have pulmonary involvement, such as inflammation or impaired lung function. Increasing evidence indicated chronic gut and lung disease share key conceptual features with the disorder and dysregulation of the microbial ecosystem. However, the underlying mechanisms are not well understood. Our study is aimed to elucidate the intimate relationship between the gastrointestinal tract and respiratory tract, and uncover the mechanisms by which the gut microbiota affects the immune responses in the lungs, and vice versa.

Unknown status6 enrollment criteria

Dynamic Changes of Circulating Tumor DNA in Late Stage NSCLC Patients

CarcinomaNon-Small-Cell Lung5 more

A multi-centre observational, non-interventional study is to dynamically monitor the changes of circulating tumor DNA (ctDNA) in late stage NSCLC patients under Gefitinib treatment.

Unknown status7 enrollment criteria

Respiratory Microbiome in COPD and Associated Inmune Response.

Pulmonary Disease (COPD)Chronic Obstructive

Hypothesis: COPD patients with frequent exacerbations have different pulmonary and systemic immune response than COPD patients without frequent exacerbations and this is related to their microbiome.

Unknown status7 enrollment criteria

Registry of COPD Patients From Outpatient Polyclinic Healthcare Institutions of the Russian Federation...

Pulmonary DiseaseChronic Obstructive

To describe the clinical profile of COPD patient who is under outpatient surveillance at polyclinic institutions of Moscow (including demographic data (age, gender, ethnicity, occupation), smoking status, disease duration, disease severity grade, distribution by disease phenotype, disease exacerbation rate in the setting of real-life clinical practice).

Unknown status5 enrollment criteria

Biomarker in Lung Diseases

Lung Diseases

Disease related biomarkers have been established decades ago, e.g. blood glucose for diabetes diagnosis and management. Their discovery has grown dramatically during the past decade and they have the potential to lead the physician in diagnosis -especially differential diagnosis - and therapy. However, a specific serum-biomarker in lung diseases has not been established. Aim of the current study is to to measure lung specific proteins in the serum in patients with various lung diseases and to correlate those with disease severity, lung function and other laboratory results

Unknown status4 enrollment criteria

Long-term Oxygen Treatment (LTOT) in Chronic Obstructive Pulmonary Disease: Factors Influencing...

Chronic Obstructive Pulmonary Disease

The purpose of this prospective cohort study is to determine factors involved in survival in new COPD patients treated by long-term oxygen therapy. Background: long-term oxygen therapy is indicated in patients with severe COPD. No studies have been performed in the past 20-25 years to examine the results of early clinical trials. Further studies are necessary to understand the utility of oxygen therapy in severe COPD.

Unknown status10 enrollment criteria

The Vancouver-BOLD Study: The Burden of Chronic Obstructive Lung Disease

Chronic Obstructive Lung Disease

This is a study of the lung health of the population of Vancouver and the extent of, and the risk factors for, chronic obstructive lung disease.

Unknown status4 enrollment criteria

Respiratory Virus Infections in Acutely Hospitalized Adult Patients With Pulmonary and Extrapulmonary...

Respiratory Virus InfectionStroke2 more

Respiratory virus infections are one of the major causes of hospitalizations, and outbreaks of respiratory virus infection have led to severe economic loss. In addition to pulmonary complications, respiratory viruses can also lead to non-pulmonary complications. However, many previous studies on the complications of respiratory viruses are retrospective in nature, and therefore many patients with respiratory virus infection may not be tested. Furthermore, these studies did not take into account that respiratory viruses can be found in some asymptomatic individuals. The aim of this study is to capture the burden of respiratory viruses in patients with acute pulmonary and extrapulmonary complications. We will recruit patients admitted to our hospital with acute coronary syndrome, stroke and exacerbation of underlying lung diseases. We will collect saliva from these patients and test for respiratory viruses. As controls, we will recruit asymptomatic patients at the out-patient clinic for follow up of chronic heart, lung or neurological diseases. We anticipate that this study will greatly enhance our understanding of the epidemiology of respiratory viruses in acutely hospitalized patients. Our findings will be important for clinicians, public health practitioners and scientists.

Unknown status17 enrollment criteria

GIRH Chronic Obstructive Pulmonary Disease Observational Study

Chronic Obstructive Pulmonary Disease

The purpose of this study is to establish the large COPD cohort and biological database in China, aiming for precision medicine to optimize diagnosis and treatment choices.

Unknown status2 enrollment criteria

Diagnostic Values of C-reactive Protein and Procalcitonin in Predicting Bacterial Infection in Acute...

Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease is a serious disease . Exacerbations of Chronic obstructive pulmonary disease is an acute worsening condition of Chronic obstructive pulmonary disease, which always accompanied by clinical symptoms such as, shortness of breath and increased production of sputum. Respiratory infection (bacteria or viruses or mixed) is thought to be the main cause in most exacerbations.

Unknown status3 enrollment criteria

Need Help? Contact our team!


We'll reach out to this number within 24 hrs