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Active clinical trials for "Lung Neoplasms"

Results 6491-6500 of 6521

Multi-Indication, Retrospective Oncological Study to Validate the Accuracy in Predicting TTP by...

Non-Small Cell Lung CancerSmall Cell Lung Cancer3 more

This is a retrospective observational, open label study to evaluate and prospectively validate in a blind manner the accuracy of predicting treatment outcomes by PrediCare in individual patients with Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Castration-Resistant Prostate Cancer, Breast Cancer & Colon Cancer under the treatment with the mono- and combination drug protocols for the 1st and 2nd line treatment, approved to the market as a Standard of Care

Unknown status80 enrollment criteria

Dynamic Changes of Circulating Tumor DNA in Late Stage NSCLC Patients

CarcinomaNon-Small-Cell Lung5 more

A multi-centre observational, non-interventional study is to dynamically monitor the changes of circulating tumor DNA (ctDNA) in late stage NSCLC patients under Gefitinib treatment.

Unknown status7 enrollment criteria

Acquired Resistant Mechanism of the First-generation EGFR TKIs

Non-small Cell Lung CancerAquired Resistance1 more

Patients with advanced non-small-cell lung cancer (NSCLC) harboring sensitive epithelial growth factor receptor (EGFR) mutations invariably develop acquired resistance to EGFR tyrosine kinase inhibitors (TKIs). Identification of actionable genetic mutations can be helpful for guiding the subsequent treatment. This study aimed to analyze the genetic profile of NSCLC harboring acquired resistance to the first-generation EGFR TKIs using next generation sequencing (NGS).

Unknown status7 enrollment criteria

Verification of Novel Survival Prediction Algorithm for Patients With NSCLC Spinal Metastasis

Spinal MetastasesNon-Small-Cell Lung Cancer Metastatic

The purpose of this study is to learn whether our own made predictive algorithm can be used as a clinical practical decision support for patients with NSCLC spinal metastasis. The scoring system consists of the use of EGFR-TKI, KPS, Age, SCC, CA125 and smoking history. By predicting survival doctors could determine which patients are suitable for palliative therapy.

Unknown status7 enrollment criteria

Circulating Tumor DNA Detection in Surveillance of Surgical Lung Cancer Patients

CarcinomaNon-small-cell Lung Cancer1 more

Conduct a prospective study to confirm blood and urine ctDNA detection value in non-small-cell lung cancer patients.

Unknown status13 enrollment criteria

The Value Of Circulating Tumor Cells In Patient With NSCLC In Postoperative Recurrence Monitoring...

Non-small-cell Lung Carcinoma

The purpose of this study is to assess the value of circulating tumor cells (CTC)for non-small cell lung cancer in the postoperative recurrence monitoring by comparing the CTCs, CT and tumor markers at different time points.The time of CTC and carcinoembryonic antigen(CEA) detection is baseline, 2~7 days, 3 months, 6 months, 12 months, 24 months, 36 months after the surgery. And the time of CT detection is 6 months, 12 months, 24 months, 36 months after the surgery.

Unknown status10 enrollment criteria

PCORI-CER-1306-03385 Lung Cancer Screening Readiness Study

Lung Cancer Screening

Investigators will administer a brief, anonymous survey at the Texas Academy of Family Physicians (TAFP) annual Primary Care Summit to better understand the readiness of primary care physicians in Texas to implement lung cancer screening programs in their practice settings.

Unknown status2 enrollment criteria

VATS Major Lung Resection for Chinese Early-stage Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

Surgery may be the best treatment choice for early stage non-small cell lung cancer. And VATS major lung resection have been preferred as a standard radical procedure for early stage non-small cell lung cancer (NSCLC).This study aim to investigate the outcome of VATS major lung resection for lung cancer as a real-world study in china.

Unknown status13 enrollment criteria

Study of Use of CTC in NSCLC

Non Small Cell Lung CancerChronic Obstructive Pulmonary Disease

The purpose of this study is to assess whether the detection of circulating tumor cells (CTC) could be used as a tool to earlier diagnose, more accurately predict treatment response / failure and predict overall survival in non-small cell lung cancer (NSCLC) patients

Unknown status27 enrollment criteria

Tissue Collection Study for Patients With Non-Small Cell Lung Cancer With Resectable Disease

Non-Small Cell Lung Cancer

A 15-gene lung signature was created to identify predictive and prognostic biomarkers for Non-Small Cell Lung Cancer (NSCLC) patients. The 15-gene signature was validated using a microarray platform with fresh frozen tumor tissue to place NSCLC patients into high risk and low risk cohorts with significantly different survivals. Using fresh frozen tissue can be challenging, so this study attempts simplify the process by migrating the 15-gene signature from fresh frozen to two alternative tissue formats: Formalin Fixed Paraffin Embedded (FFPE) and RNAlater. The gene expressions of the different tissue formats will be compared to see if the fresh frozen tissue results are similar to the alternative tissue formats.

Unknown status12 enrollment criteria
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