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Active clinical trials for "Macular Edema"

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Reduction of Foveal Sensitivity in Eyes With Diabetic Macular Edema

Diabetic RetinopathyClinically Significant Macular Edema

Clinically significant macular edema (CSME) is a thickening of the macula associated with the risk of visual loss, which increases its centre is involved. Functional evaluation of the macula relies on best corrected visual acuity; however, neural dysfunction in diabetic eyes appears before retinal thickening and visual loss. Retinal sensitivity decreases in eyes with CSME, but it is unknown whether it differs between eyes with and without centre thickening. Aim: To compare the reduction of foveal sensitivity in eyes with CSME, with and without centre thickening.

Completed7 enrollment criteria

Pilot Study of OCT Versus Fluorescein Angiography in DME

Diabetic Macular Edema

Diabetic Macular Edema (DME), which can happen as a complication of diabetes, occurs when fluid and proteins collect in the macula (the yellow central area of the retina). The fluid can cause swelling which in turn can lead to worsening central vision. The purpose of this study is to see if the study device (Swept Source Optical Coherence Tomography or SS-OCT) is able to diagnose DME as well as an already approved imaging procedure called fluorescein angiography (FA). FA is standard of care and would be conducted regardless of study participation. The dye used in FA, which can cause allergic reactions in some patients and is not used in pregnant women, is not needed with the study device. Another purpose of the study is to avoid the risk of administering the FA dye if possible.

Completed10 enrollment criteria

A Retrospective Study of Anti-Vascular Endothelial Growth Factor (VEGF) Injections for Retinal Vein...

Retinal Vein OcclusionMacular Edema

This retrospective data review study will evaluate anti-VEGF injections for retinal vein occlusion (RVO) or diabetic macular edema (DME).

Completed3 enrollment criteria

Time to Treatment Utilizing a Tele-Retinal Referral System for wAMD and DME: A Pilot Study

Wet Age Related Macular DegenerationDiabetic Macular Edema

In this province, optometrists are often responsible for contacting the retinal specialists' office to arrange patients to be examined for suspected emergencies or more routine referrals related to the eye. This is often done by faxing a referral form to the specialists' office, where the retinal specialist will examine the information presented in the referral form and make a decision on when the patient should be seen. This current method has some important considerations, such as the difficulty of transmitting clear images of the back of the eye over fax. Having this information could help the retinal specialist in determining when the patient should be seen, especially in terms of booking additional tests or when treatment should be given. Teleophthalmology is a branch of telemedicine that delivers eye care through digital equipment and telecommunications technology. It offers some unique advantages, such as the ability to be integrated with electronic health records, the ability to be viewed by multiple members of the health care team, and potentially reduce wait times and travel times to the ophthalmologist. However, there is no comparison known to the study team between whether patients being referred from optometrists to retina specialists through a teleophthalmology system will be treated earlier than patients through a conventional fax system. This study aims to examine and provide more information on this topic.

Completed7 enrollment criteria

Dexamethasone-Implant for the Treatment of Macula Edema Due to Irvine Gass Syndrome

Macular EdemaVisual Acuity

To analyze macula edema formation after cataract surgery called Irvine-Gass-Syndrome.

Completed2 enrollment criteria

Prevalence of DIAbetic RETinopathy and Impact of Genetic Factors in the Development of Diabetic...

Diabetic RetinopathyDiabetic Macular Edema1 more

The aim of the study is to find out prevalence and individual stages of Diabetic Retinopathy in patients with type 1 and type 2 DM verified based on complex ophthalmologic measurements in Slovak Republic. The outcome of the project will be epidemiology survey, prevalence of diabetic retinopathy (DR) and diabetic macular edema (DME) in relation to type and duration of diabetes mellitus and risk factors. Project will also identify genetic factors linked with the diseases.

Completed11 enrollment criteria

Study of OZURDEX® in the Treatment of Diabetic Macular Oedema (DME) in Australia - The AUSSIEDEX...

Diabetic Macular Oedema

This prospective study will assess Ozurdex in the treatment of Diabetic Macular Oedema in clinical practice.

Completed3 enrollment criteria

Angiographie and OCT in Macula and Retinal Diseases

Macular Edema

The purpose of this study is to investigate the morphological and angiological retinal changes in different macular diseases.

Completed6 enrollment criteria

Multimodal Ophthalmic Imaging

Retinitis PigmentosaMaculopathy14 more

Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems are limited in resolution, speed, or access to certain structures of the eye. The use of a high-resolution imaging system improves the resolution of ophthalmoscopes by several orders of magnitude, allowing the visualization of many microstructures of the eye: photoreceptors, vessels, nerve bundles in the retina, cells and nerves in the cornea. The use of a high-speed acquisition imaging system makes it possible to detect functional measurements such as the speed of blood flow. The combination of data from multiple imaging systems to obtain multimodal information is of great importance for improving the understanding of structural changes in the eye during a disease. The purpose of this project is to observe structures that are not detectable with routinely used systems.

Unknown status15 enrollment criteria

Changes in Optical Coherence Tomography Leakage Mapping in Diabetic Macular Edema After Conbercept...

Diabetic Macular Edema

Eyes with diabetic macular edema requiring conbercept treatment will be followed up for one month. Before treatment, one week after treatment and one month after treatment, the eyes will be examined by optical coherence tomography (OCT) and optical coherence tomographic angiography (OCTA). The changes of macular edema will be observed and analyzed by OCT leakage mapping software, and the relationship between the changes of macular edema and visual acuity will be analyzed.

Unknown status13 enrollment criteria
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