Statins and Breast Cancer Biomarkers
Breast CancerThere is laboratory evidence that cholesterol lowering medications (statins) inhibit the growth of breast cancer cells. Clinical studies are controversial but some show that women taking statins are less likely to get breast cancer. This ongoing randomized trial compares one-year of atorvastatin (Lipitor™) or placebo for lowering mammography-defined breast density and other surrogate markers associated with breast cancer risk.
Weight Control Programs in Women Who Have Undergone Surgery for Early Stage Breast Cancer
Breast CancerWeight ChangesRATIONALE: Measuring changes in body weight and body composition in women with early-stage breast cancer may help doctors plan the best weight control program and improve patients' quality of life. It is not yet known which program is most effective in women with breast cancer. PURPOSE: This randomized clinical trial is comparing three weight control programs to see how well they work in women who have undergone surgery for early stage breast cancer.
Menopausal Symptoms in Women With Breast Cancer or At High Risk of Breast Cancer Treated on Another...
Breast CancerHot FlashesRATIONALE: Gathering information about the frequency and intensity of hot flashes in patients with breast cancer and in patients who have a high risk of developing breast cancer may help doctors learn more about menopausal symptoms. PURPOSE: This clinical trial is looking at menopausal symptoms in women with breast cancer or at high risk of breast cancer who received treatment on another clinical trial.
Ultrasound Elastography of Breast Lesions
Breast NeoplasmsOur hypothesis is that the addition of ShearWave Elastography (SWE) to a conventional breast ultrasound examination provides useful information for the radiologist when imaging lesions in the breast, as compared to conventional grayscale ultrasound alone.
Post Marketing Surveillance Study To Observe Safety And Efficacy Of Aromasin In The Patients With...
Breast CancerThis non-interventional study is to monitor use in real practice in Korea including adverse events on Aromasin (Exemestane).
Optical Spectroscopy During Breast Cancer Surgery and Core Needle Biopsy
Breast CancerThe objective of the proposed research is to develop new diagnostic modalities based on optical spectroscopy (auto fluorescence, absorption, and scattering) for the diagnosis of breast cancer and test its performance as an adjunct to core needle biopsy. For the surgery part of the study, all patients scheduled to have a mastectomy or lumpectomy for the treatment of breast cancer will be asked if they would be willing to participate in this study. For the core needle biopsy part of the study, patients with a higher pre-probability of cancer (based on mammography) will be recruited to increase the number of patients with malignant lesions and enrolled in this investigation.
Evaluation of Brain Function Before and After Standard Chemotherapy for Early Breast Cancer
Early Breast CancerPrimary Objective To investigate and clearly document the presence and extent of cognitive decline, if any, in women of Asian origin following standard-dose systematic adjuvant chemotherapy for the treatment of breast cancer Investigation and establishment of a relationship between degree of oxidative DNA and lipid damage as indicated by plasma and urinary biochemical markers. Secondary Objective • To validate the use of hydrogen peroxide and serum amyloid as biomarkers of damage
Early Detection of Breast Cancer Using Tomosynthesis Imaging
Breast NeoplasmsThe purpose is to develop digital tomosynthesis to improve the detection of breast cancers. The aims are optimizing digital mammography and tomosynthesis acquisition, creating visualization tools, prospective pilot studies to evaluate radiologist performance, and computer-aided detection.
A Study to Evaluate Safety and Tolerability in Patients With Metastatic Breast Cancer Receiving...
Breast NeoplasmThis is a study to evaluate the safety and tolerability of Caelyx used for the treatment of metastatic breast cancer (MBC), focusing on infusion reaction and palmar-plantar erythrodysesthesia (PPE).
Cognitive Function in Older Women With Stage I, Stage II, or Stage III Breast Cancer Receiving Hormone...
Breast CancerRATIONALE: Gathering information about cognitive function over time in postmenopausal women with breast cancer may help doctors learn about the long-term effects of aromatase inhibitor therapy and plan the best treatment. PURPOSE: This clinical trial is studying cognitive function in older postmenopausal women with stage I, stage II, or stage III breast cancer receiving hormone therapy and in healthy volunteers.