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Active clinical trials for "Marijuana Abuse"

Results 201-210 of 435

Atomoxetine Treatment for ADHD and Marijuana Dependence

Marijuana AbuseAttention Deficit Disorder With Hyperactivity

The aim of the study is to determine if atomoxetine treatment combined with motivational enhancement therapy is effective in reducing marijuana use in adult individuals with attention-deficit hyperactivity disorder and marijuana dependence.

Completed21 enrollment criteria

The Teen Marijuana Check-Up

Cannabis AbuseCannabis Dependence

This behavioral research is an efficacy trial evaluating an intervention called "The Teen Marijuana Check-Up" with non-treatment seeking adolescent marijuana users.

Completed7 enrollment criteria

Effectiveness Study of Dronabinol and BRENDA for the Treatment of Cannabis Withdrawal

Marijuana Dependence

This treatment study is targeted specifically for those who want to stop using marijuana. We want to find out if patients who are dependent on marijuana and want to stop using are helped by a combination of the drug dronabinol and six sessions of individual therapy (BRENDA). Dronabinol is a pill form of the active ingredient in marijuana (THC). Currently, dronabinol is approved for the treatment of nausea in people receiving cancer chemotherapy and as an appetite stimulant in people with AIDS. In some studies, dronabinol reduced the amount of psychological and physical discomfort experienced when people stopped using marijuana. One purpose of our study is to see if people who are on dronabinol have fewer problems with psychological and physical discomfort than those who are on a placebo. In addition to treatment, this research trial will also be measuring the reactions of subjects to drug-related cues, and also to computer-presented tasks unrelated to drug use. We may examine whether the response to these cues/tasks either predicts treatment outcome, or is affected by your treatment. This information may also help us to understand the ways in which chronic drug use causes changes in our subjects' mental functioning and how those changes respond to treatment. In addition to participation in the treatment research trial, some subjects may be asked to undergo a brain scan in an MRI. The purpose of the brain scan research project is to measure brain reactions with a non-invasive, non-radioactive imaging technique known as fMRI (functional magnetic resonance imaging) in marijuana subjects before and after treatment with the medication dronabinol or with an inactive substance (placebo).

Completed23 enrollment criteria

Therapeutic Substance Abuse Treatment in Pregnancy - 1

Alcohol AbuseCocaine Abuse1 more

The purpose of this study is... To assess whether a behavioral treatment that combines motivational enhancement and cognitive skills training therapy (MET-CBT) is more effective than brief advice in: 1) decreasing use of a full range of psychoactive substances (e.g. marijuana, cocaine, methamphetamines, alcohol, nicotine, opioids) in pregnant substance using and dependent women; 2) decreasing HIV risk behavior; 3) improving birth outcomes (longer gestations and greater birth weight).

Completed3 enrollment criteria

Efficacy Study of Quetiapine Plus Topiramate for Reducing Cannabis Consumption and Bipolar Mania...

Bipolar DisorderCannabis-Related Disorder

The objectives of this study are to determine whether this treatment may be useful for reducing cannabis consumption; reducing symptoms of bipolar mania; and weight mitigation therapy for individuals on psychopharmacotherapy.

Completed25 enrollment criteria

Gabapentin Treatment of Cannabis Dependence

Cannabis Dependence

This is a study to evaluate the efficacy of the medication gabapentin in treating persons with cannabis dependence.

Completed8 enrollment criteria

Atomoxetine for Treating Marijuana-Abusing Adolescents Who Have Attention Deficit Hyperactivity...

Attention Deficit Disorder With HyperactivityMarijuana Abuse

Attention Deficit Hyperactivity Disorder (ADHD) is common among adolescents seeking treatment for marijuana dependence. The purpose of this study is to determine the use of atomoxetine in treating adolescents who abuse marijuana and have ADHD. In addition, this study will assess whether atomoxetine reduces ADHD symptoms as compared to a placebo. Finally, the study will determine whether atomoxetine improves treatment retention and progress in adolescents with ADHD and marijuana dependence.

Completed19 enrollment criteria

Effectiveness of Buspirone and Motivational Enhancement Therapy for the Treatment of Marijuana Dependence...

Marijuana AbuseMood Disorders

This study will assess the effectiveness of a combination of buspirone and motivational interviewing therapy in the treatment of marijuana dependence.

Completed12 enrollment criteria

Divalproex Sodium (Depakote) for Explosive Tempers in Adolescents and Adults

Attention Deficit and Disruptive Behavior DisordersMarijuana Abuse

The purpose of this study is to compare the effectiveness of divalproex sodium (Depakote) versus placebo in treating disruptive behavior disorder and explosive tempers in adolescents and adults.

Completed26 enrollment criteria

Substance Dependent Teens - Impact of Treating Depression Study 1 - 1

Alcohol-Related DisordersMarijuana Abuse1 more

The purpose of this study is to evaluate the impact of treating depression on substance dependent teens.

Completed5 enrollment criteria
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