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Active clinical trials for "Menorrhagia"

Results 101-110 of 154

Tamoxifen to Reduce Unscheduled Bleeding in New Users of the Levonorgestrel-releasing Intrauterine...

MenorrhagiaMetrorrhagia1 more

This study evaluates the ability of tamoxifen to improve frequent or prolonged bleeding in new users of the 52mg levonorgestrel-releasing intrauterine device (IUD). Half of participants will receive a course of tamoxifen three weeks after insertion of the IUD, while the other half of participants will receive a course of placebo.

Completed14 enrollment criteria

IL-11 in Women With Von Willebrand Disease and Refractory Menorrhagia

Von Willebrand Disease

The purpose of this study is to determine the efficacy and safety of rhIL-11, when given subcutaneously for six consecutive months, in reducing menstrual blood loss in women with type 1 von Willebrand disease and refractory menorrhagia. Efficacy will be measured by subjective bleeding severity scale and pictorial bleeding chart. Safety will be measured by the frequency of adverse events, including fever, headache, fatigue, myalgias, arthralgias, fluid retention, or edema.

Completed12 enrollment criteria

Vaginal Misoprostol for Cervical Ripening Prior to Endometrial Biopsy

MenorrhagiaEndometrial Biopsy1 more

The purpose of this study is to determine whether using Misoprostol vaginally before an office endometrial biopsy is performed, will make it easier, more successful and less painful to do the procedure. The investigators' hypothesis is that vaginal Misoprostol 12 hours prior to endometrial biopsy will increase the ease of performing office endometrial biopsy by reducing the need to use a tenaculum or a cervical dilator to achieve passage of a biopsy pipelle.

Withdrawn6 enrollment criteria

Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual Bleeding:...

LeiomyomaUterine Fibroids1 more

The primary objective of this study is to test the hypothesis that a minimum 75% volume radiofrequency ablation of fibroids associated with menorrhagia results in reduction of menstrual bleeding.

Withdrawn36 enrollment criteria

Ultrasound Evaluation Versus Direct Measurement of Uterine Cavity Length

DysmenorrheaHeavy Menstrual Bleeding1 more

To determine if uterine cavity length on transabdominal pelvic ultrasound corresponds to uterine cavity length at time of IUD insertion. If transabdominal pelvic ultrasound is validated as a tool for measuring uterine cavity length, it can be used to guide physicians and subsequently patients in IUD insertion planning.

Completed5 enrollment criteria

Treatment and Management of Women With Bleeding Disorders

MenorrhagiaBlood Coagulation Disorders3 more

The purpose of the study is to determine whether oral contraceptives, desmopressin acetate, and/or tranexamic acid are effective in the treatment of women with menorrhagia who are diagnosed with a bleeding disorder.

Completed19 enrollment criteria

Prediction of Response to IUCD Associated Menorrhagia Using Doppler

Women's Health: Amenorrhea/Dysmenorrhea

Studying the efficacy of uterine artery doppler in predicting response to mefenamic acid in women having IUCD associated menorrhagia

Completed11 enrollment criteria

Relationship Between Bladder Distention and Hysteroscopy Application

Menorrhagia

The purpose of the study is to investigate the advantages and disadvantages of bladder filling during hysteroscopy procedure.

Completed7 enrollment criteria

Lysteda Pediatric Research Equity Act (PREA) Pharmacokinetic Study in Adolescent Females With Heavy...

Menorrhagia

This is a Phase 4, randomized, 2-way crossover, pharmacokinetic study of Lysteda (tranexamic acid) tablets administered as single doses of 0.65 g and 1.3 g in fasting adolescent female subjects ages 12-16 years with heavy menstrual bleeding.

Completed26 enrollment criteria

Surgical Success After Laparoscopic vs Abdominal Hysterectomy

MetrorrhagiaMenorrhagia5 more

The purpose of the proposed pilot study is to investigate the effectiveness, cost, safety, and long-term impact on quality of life of laparoscopic hysterectomy (LH) in relation to abdominal hysterectomy (AH) for the treatment of benign gynecologic disease in women through a randomized surgical trial.

Completed12 enrollment criteria
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