
Lifestyle Intervention for Polycystic Ovary Syndrome: Pulse-Based Diet and Exercise
Polycystic Ovary SyndromeMetabolic SyndromeThe purpose of our study is to evaluate the effectiveness of a lifestyle program for women with Polycystic Ovary Syndrome (PCOS). The investigators want to assess the effect of a pulse-based diet (i.e. a diet that contains lentils, chick-peas, peas, and beans) and aerobic exercise for improving PCOS disease features and risk factors for metabolic syndrome. We would like to determine the therapeutic effects of a lifestyle program that combines a pulse-based diet and exercise on the multiple disease measures of PCOS and metabolic syndrome.

Effects of Leptin Replacement in Children
ObesityMetabolic Syndrome1 moreTo assess the endocrine and immune effects of leptin replacement in leptin-deficient children, from a consanguineous family. The hypothesis is that leptin replacement will have significant effects on endocrine function.

Efficacy of Nicotine Acid on Dyslipidaemia in Patients With Metabolic Syndrome
Metabolic SyndromeDyslipidaemiaPlacebo controlled evaluation of effectiveness of nicotine acid in treatment of postprandial dyslipidemia in patients with metabolic syndrome. Nicotine acid decreases postprandial hyperlipidaemia in patients with metabolic syndrome which reduces the low-grade inflammation and the risk of atherosclerosis.

Methionine-Restriction Diet (MRD) in Obese Adults With Metabolic Syndrome
Metabolic SyndromeThe purpose of this study is to determine if limiting dietary methionine (MET), one of the 10 essential amino acids (which make up proteins), causes weight loss and/or improves glucose metabolism.

Effect of Irvingia Gabonensis (Bush Mango)on Parameters Associated With Metabolic Syndrome
Metabolic SyndromeObesity1 moreThe study investigated the use and efficacy of the seeds of African bush mango (Irvingia gabonensis)to control body weight, blood lipids and hormones in overweight and obese people.

A Randomized, Double-Blind Trial Comparing the Efficacy and Safety of Fenofibrate, Metformin, Their...
Patients With Metabolic SyndromeThe purpose of this study was to study the effect of different combinations of fenofibrate and metformin on the cluster of metabolic syndrome (MetS) biochemical abnormalities, and to determine the dose combination allowing normalization of MetS patients.

A Phase IIa Proof-of-concept Study of NC-503 in Patients With Type II Diabetes
Diabetes MellitusType 21 moreThe main objectives of the current study are to establish the safety and clinical proof-of-concept of NC-503 in inadequately controlled patients with Type 2 diabetes and features of metabolic syndrome treated with either metformin, a sulfonylurea agent, or metformin in combination with a sulfonylurea agent.

Study to Determine if Olmesartan Medoxomil Has the Potential to Benefit the Cardiovascular System...
Metabolic SyndromeHypertensionThis study will analyse the dose-dependent effect of olmesartan medoxomil on the change in arterial stiffness in subjects with hypertension and metabolic syndrome

Reducing the Overall Risk Level in Patients Suffering From Metabolic Syndrome
HypertensionDyslypidaemiaThis study will evaluate the efficacy of a multi factorial preventive scheme of action (including fluvastatin and valsartan) to reduce the overall risk level in patients with metabolic syndrome.

The Effects of Aripiprazole on Patients With Metabolic Syndrome
SchizophreniaSchizoaffective Disorder2 moreThe primary goal of this study is to assess the effect of aripiprazole on patients who developed metabolic syndrome while taking other second generation antipsychotic medications.