Efficacy and Safety of Oral Rifaximin in Patients With Active Microscopic Colitis
Microscopic ColitisThis is an open label study looking at rifaximin therapy for the treatment of microscopic (collagenous or lymphocytic) colitis.
Modulation of Intestinal Barrier Function and Inflammation Via Butyrate-promoting Dietary Fibre...
Microscopic ColitisThis study examines how a fermentable dietary fibre known to promote butyrate production impacts intestinal barrier function, intestinal microbiota, intestinal inflammation, and gastrointestinal symptoms in patients with microscopic colitis.
Systems Biology of Gastrointestinal and Related Diseases
Ulcerative ColitisCrohn Disease20 moreThis is a longitudinal observational study on patients with gastrointestinal and related disease. The study will be conducted for at least 10 years, following each participant over time, as they either go through relapses and remissions, or progression of their disease.
Identification/Characterization of Changes in Microscopic Colitis
ColitisMicroscopicThe goal of this study is to establish a prospective observational cohort of adult patients with microscopic colitis and collect clinical information and specimens over the course of their treatment. This information will be used in order to establish a patient registry with detailed clinical data and a specimen repository for future research as well as to specifically identify genetic and molecular characteristics associated with microscopic colitis.
Faecal Microbiota Transplantation for Microscopic Colitis
Microscopic ColitisA pilot study investigating if orally administrated faecal microbiota transplantation capsules have the potential to treat active microscopic colitis.
External Validation of a Microscopic Colitis Clinical Scoring System in Patients With Chronic Watery...
Microscopic ColitisChronic watery diarrhoea is a very common problem in the population and most of these patients will be referred for colonoscopy. If no macroscopic findings are observed during colonoscopy to justify the diarrhoea, serial colonic biopsies will be taken to rule out Microscopic Colitis (MC). However, it has been estimated that only 10-15% of these patients will be diagnosed with MC after colonoscopy. Therefore, about 80% of the biopsies collected and analysed will not be useful to establish a diagnosis, considerably increasing costs. To predict the risk of developing MC, a new promising clinical scoring system has been recently developed. This score will be useful in the diagnostic work-up of chronic watery diarrhoea to prioritize colonoscopy with stepwise colonic biopsies in patients with a positive highly specific score for MC. In cases with a negative score, colonoscopy plus biopsies should be performed only if other diagnostic tests are negative. The aim of this current study is to externally validate the new scoring system to predict MC in patients with chronic watery diarrhoea.
Efficacy and Safety of Budesonide MMX® vs. Budesonide CR for Induction of Remission in Microscopic...
Microscopic ColitisThe purpose of this research study is to compare how well two formulations of budesonide (budesonide MMX [Cortiment] and budesonide CR [Entocort]) work for treating patients with microscopic colitis.
Treatment of Microscopic Colitis
ColitisThe study compares the effect of Budesonide, Bismuth and fiber in patients with microscopic colitis
Budesonide for Induction of Remission in Incomplete Microscopic Colitis
Incomplete Microscopic ColitisThe purpose of this study is to demonstrate the efficacy of budesonide for the treatment of active incomplete microscopic colitis.
Budesonide Treatment for Lymphocytic Colitis
Microscopic ColitisThe purpose of this study is to determine whether orale budesonide is effective in the treatment of lymphocytic colitis