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Active clinical trials for "Mitral Valve Insufficiency"

Results 261-270 of 367

Mitral Valve Replacement With MValve Dock and Lotus

Mitral Valve Regurgitation

This study evaluates the MValve mitral prosthesis in conjunction with a Lotus transcatheter heart valve (THV) for mitral valve replacement in subjects at high risk for conventional mitral valve replacement or repair surgery.

Unknown status16 enrollment criteria

MitraClip System in Australia and New Zealand

Mitral Regurgitation

The primary objective of the MitraClip System Australia and New Zealand (ANZ) Clinical Trial is to gather real-world clinical and health-economic outcome data to support the long-term safety, efficacy and economic value of the MitraClip System in the continuum of therapies for treating MR. Specifically, the following clinical and economic data will be collected: New York Heart Association (NYHA) Functional Class, Six-Minute Walk Test (6MWT) distance, quality of life (QOL) information, echocardiographic measures of left ventricular size and function, and data associated with the index hospitalization, rehospitalizations, concomitant medications and discharge facility to support the MitraClip System economic analysis.

Terminated15 enrollment criteria

A Feasibility Registry of Actigraphy Monitoring in Degenerative Mitral Regurgitation Subjects Receiving...

Mitral Regurgitation

A prospective, open-label, and multi-centered feasibility registry.

Terminated5 enrollment criteria

Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary...

Cardiovascular Diseases

The objective of this trial is to compare the safety, the efficacy and the cost-effectiveness of 2 therapeutic strategies (optimal standard of care therapy alone versus percutaneous MitraClip procedure and optimal standard of care therapy) in patients with severe secondary mitral regurgitation. This trial is a French, multicenter and randomized trial. Patients enrolled will be clinically followed for 2 years (phone call at 1 month, clinical visit at 6 months, 12 months and 24 months).

Unknown status29 enrollment criteria

Mitralign Percutaneous Annuloplasty System for Chronic Functional Mitral Valve Regurgitation

Mitral Valve Regurgitation

The purpose of this study is to test the safety and device performance of the Mitralign system ("MPAS") to treat functional mitral valve regurgitation.

Unknown status15 enrollment criteria

Safety and Performance Study of the MitralStitch Repair System.

Mitral Regurgitation

The main objective is to assess the effectiveness and safety of the MitralStitch repair system in patients with moderate to severe and severe mitral regurgitation.

Unknown status28 enrollment criteria

Mitral Valve Repair Combined Coronary Artery Bypass Grafting(CABG) Verus CABG Alone on Functional...

Coronary Artery DiseaseMitral Valve Insufficiency

Coronary artery bypass grafting(CABG) is an effective procedure in treating severe coronary artery disease(CAD). Optimal surgical method for CAD patients with functional ischemic mitral regurgitation(FIMR) is still controversial. This study will evaluate the different effectiveness of CABG plus mitral valve annuloplasty versus CABG alone on patients with moderate FIMR.

Unknown status14 enrollment criteria

Abrogation of Mitral Regurgitation Using the MitraClip System in High-Risk Patients Unsuitable for...

Mitral Regurgitation

The primary objective in this randomized trial is to evaluate the safety and efficacy of a MitraClip treatment in symptomatic patients with severe mitral regurgitation in comparison to the previous default medical treatment - in a study population who is not amenable for the conventional surgical approach as current gold standard.

Unknown status9 enrollment criteria

Treatment of Heart Failure and Associated Functional Mitral Valve Regurgitation

Mitral Valve Regurgitation

The objective of the study is to evaluate the safety and performance of the ARTO System in patients with mitral valve regurgitation (MR) associated with congestive heart failure (CHF).

Unknown status19 enrollment criteria

Examination of Valve Insufficiency Before and After MitraClip or TAVI Procedure by 3D Echocardiography...

Development of Standardized Assessment TAVI and MitraClip Procedures by EchocardiographyAortic Stenosis1 more

Aim of the study is the definition of criteria for a standardized assessment of heart function by 3D echocardiographic procedures. Standardized criteria will be defined to assess aortic valve insufficiency after TAVI and success of mitral valve replacement respectively.

Completed12 enrollment criteria
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