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Active clinical trials for "Heart Failure"

Results 4121-4130 of 4671

Exploration of Clonal Hematopoiesis of Indeterminate Potential in Non-ischemic Heart Failure With...

Heart Failure With Reduced Ejection Fraction

Clonal hematopoiesis of indeterminate potential (CHIP) refers to a phenomenon in which blood cells with somatic mutation circulate in the peripheral blood due to abnormal proliferation and differentiation of mutant hematopoietic cells. CHIP is considered one of the aging phenomena, and the mutant blood cells increased by CHIP cause chronic inflammation, thereby increasing the occurrence of atherosclerotic cardiovascular disease. Therefore, CHIP is known to be closely related to poor prognosis of ischemic heart failure. Meanwhile, chronic inflammation may be involved in the development of non-ischemic myocardial disease, which is one of the major causes of heart failure. This study will identify CHIP and perform NLRP3 inflammasome assay in 100 non-ischemic heart failure patients and evaluate the relationship between CHIP and inflammation, imaging markers of heart failure, Left ventricle reverse remodeling after guideline-directed medical treatment, and prognosis of heart failure with reduced ejection fraction.

Completed7 enrollment criteria

Heart Failure Treatment Pattern Analysis of HF Patients in HF Centers and Non-HF Centers in China...

Heart Failure

This is a retrospective, researcher-initiated, database-based study that will retrospectively observe the treatment and medication patterns of about 22,500 patients with heart failure from 25 heart failure centers and 25 non-heart failure centers in the database of heart failure center. The proportion of patients with heart failure treatment drugs reaching the target dose recommended in the guidelines and discontinuation rate will be observed at 1 month, 3 months and 12 months follow up time point. The purpose of this study is to illustrate the current HF treatment status in HF center hospitals and non-HF center hospitals, which may provide insights for improving the clinical practice of heart failure treatment in China, and promote the standardization of heart failure treatment in China.

Completed4 enrollment criteria

Eosinophil Indices in Patients With Acute Heart Failure

Acute Heart FailureReduced Systolic Function

All consecutive patients admitted to the intensive care unit (ICU) with ADHF between January 2017 and December 2021 were enrolled in this retrospective study. All-cause mortality and MACE were assessed with respect to relationships with eosinophil indices, including neutrophil-to-eosinophil ratio (NER), leukocyte-to-eosinophil ratio (LER), eosinophil-to-lymphocyte ratio (ELR), and eosinophil-to-monocyte ratio (EMR).

Completed2 enrollment criteria

Study of the Prognosis of Patients With Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction

Study of the prognosis of patients with heart failure with preserved ejection fraction

Completed6 enrollment criteria

Medication Adherence in Heart Failure After Hospitalisation

AdherenceMedication1 more

To explore medication adherence in patients who were hospitalised due to heart failure.

Completed4 enrollment criteria

Use of PARniv for Early Diagnosis of LVF in AECOPD

Acute Heart FailureCOPD Exacerbation

Left ventricular failure (LVF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This association is frequently underestimated with regard to the difficulty of clinical diagnosis . The investigators expect that the application of pressure support under NIV could be useful in this issue.

Completed6 enrollment criteria

Role of Sacubitril/Valsartan in Improving Provider Performance in Managing Heart Failure Under Medicare...

Heart Failure

This study evaluated the association between sacubitril/valsartan utilization and HF patients' Part A & B expenditures within the reimbursement framework of BPCI and MSSP, and identified BPCI/MSSP participants with the greatest potential for performance improvement (with respect to improving quality and efficiency of care for HF patients) through optimized utilization of sacubitril/valsartan.

Completed8 enrollment criteria

A Cohort Study to Compare the Hospitalization Between Naive Sacubitril/Valsartan and Naive ACEi/ARBs...

Heart Failure

A non-interventional retrospective cohort study conducted to compare the naive sacubitril/valsartan Heart Failure with reduced Ejection Fraction (HFrEF) patient population to a matched naive ACEi/ARB HFrEF patient population.

Completed29 enrollment criteria

Chest X-ray in Diagnosis of Heart Failure

Chest X-ray ; Heart Failure

The objective of this study is to compare the performance of x-chest ray in the diagnosis of acute cardiac insuficiency through the interpretation of a senior and a non-senior.

Completed8 enrollment criteria

A Comparison of Magnetic Resonance Imaging in Persons With Heart Failure to Health, Aged Matched...

Heart Failure

The purpose of this study is to examine the relation between the structural brain changes associated with heart failure, neurocognitive performance, and how these changes impact self-care behaviors.

Completed32 enrollment criteria
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