![AstraZeneca](https://trials-media.s3.amazonaws.com/orgs/astrazeneca.jpeg)
Estimation of the Prevalence of HER2 Low and Describe the SoC, Treatment Patterns, and Outcome in...
Breast CancerThis is a worldwide, multicenter, non-interventional, retrospective study of patient medical records from metastatic breast cancer (mBC) patients previously identified as human epidermal growth factor receptor 2 negative (HER2-neg), regardless of hormone status.
![Zealand University Hospital](https://trials-media.s3.amazonaws.com/orgs/zealand-university-hospital.jpeg)
Multimodal Pain Treatment for Breast Cancer Surgery - a Prospective Cohort Study
Breast Cancer FemalePostoperative Pain1 moreBreast cancer is one of the most common types of cancer among women worldwide. (1) Breast-conserving surgery or mastectomy is indicated for the majority of patients with this type of cancer. (2) Postoperative pain is frequent in this population, with almost 50 % experiencing acute pain and 25-60 % subsequently live with chronic pain. (3-5) Today no golden standard for postoperative pain management regarding breast cancer surgeries exists, and there is definitely room for improvement. Especially considering the large population of women with breast cancer and consequences of acute and chronic pain, such as prolonged recovery and affected quality of life. (6,7) With the present study, we aim to optimise postoperative pain treatment and investigate the effect of a standardised multimodal postoperative analgesic regimen based on previous recommendations. (4,8,9)
![Fudan University](https://trials-media.s3.amazonaws.com/orgs/fudan-university.jpeg)
Pyrotinib Plus Vinorelbine Versus Lapatinib Plus Capecitabine
Breast CancerPyrotinib Plus Vinorelbine Versus Lapatinib Plus Capecitabine
![Catherine M. Lockhart](https://trials-media.s3.amazonaws.com/orgs/catherine-m-lockhart.jpeg)
Comparative Effectiveness Analysis of Granulocyte Colony Stimulating Factor Originator Products...
CancerBreast8 moreThis comparative effectiveness and descriptive retrospective cohort study will evaluate safety and effectiveness outcomes among commercially insured adults who received a granulocyte colony stimulating factor (G-CSF) biosimilar or originator product during the first cycle of clinical guideline-indicated intermediate or high febrile neutropenia risk chemotherapy.
![SamanTree Medical SA](https://trials-media.s3.amazonaws.com/orgs/samantree-medical-sa.jpeg)
Breast Cancer Detection in Breast Surgical Specimens With the Histolog Scanner, Slide-free Confocal...
Breast CancerStudy to assess the capability of physicians (breast surgeons and pathologists) to recognize breast cancer in images of fresh lumpectomies generated with the Histolog Scanner, a recent large field-of-view confocal laser scanning medical imaging device.
![Fudan University](https://trials-media.s3.amazonaws.com/orgs/fudan-university.jpeg)
Real World Study of Lapatinib Among Metastatic Breast Cancer Patients
Breast CancerA multicenter, retrospective, real world study of Lapatinib among Metastatic Breast Cancer (MBC) Patients in Clinical Practice.
![NorthShore University HealthSystem](https://trials-media.s3.amazonaws.com/orgs/northshore-university-healthsystem.jpeg)
The MEDITATE-BC Study: Mindfulness-Enhanced Decision Intervention To Aid Treatment Election - Breast...
Breast CancerSurgeryIn this study the investigators propose to pilot test a brief, mindfulness shared decision making intervention that begins shortly after receiving a diagnosis of breast cancer. A mindfulness instructor will conduct an hour long session with consented participants before the scheduled surgical appointment. The investigators hypothesize that a mindfulness intervention delivered shortly after receiving a diagnosis of breast cancer may ultimately lead to increased decisional satisfaction and alignment to participant's values and preferences, and decreased anxiety. To measure this endpoint, participants will complete three surveys via REDCap- at baseline, before surgery, and 6 months postoperatively. Surveys will include questions on quality of life, anxiety, and participant satisfaction with the mindfulness program.
![University of Jena](https://trials-media.s3.amazonaws.com/orgs/university-of-jena.jpeg)
Analysis of Circulating Epithelial Tumor Cells in Peripheral Blood in Patients With Primary Non-metastatic...
Breast Cancer FemaleThe aim of this study was to investigate the systemic effect of radiotherapy on patients with primary non-metastatic breast cancer using CETC and to analyze possible changes in CETC quantity under adjuvant radiotherapy.
![Brigham and Women's Hospital](https://trials-media.s3.amazonaws.com/orgs/brigham-and-womens-hospital.jpeg)
Promoting Early Detection of Breast Cancer in Rural Rwanda: Impact of Community Health Worker and...
Breast CancerThis project proposes a pilot intervention in Burera District to train rural Rwandan community health workers (CHWs) in breast awareness, and to train primary care nurses at rural health centers in the assessment and management of breast complaints, with a focus on when patients must be urgently referred for more advanced evaluation. The project will randomize health centers to receive the intervention and will evaluate the impact of these trainings on nurse and CHW knowledge and skills. In order to help Rwanda prepare for national early detection efforts, the investigators will also assess the impact of these trainings on patient volume at the health center level, and visits and further diagnostic testing at the district hospital level. The investigators will also examine the impact on the length of diagnostic delays experienced by patients with a breast problem. Among those patients diagnosed with breast cancer, the investigators will also assess their stage at diagnosis.
![Instituto Nacional de Cancerologia de Mexico](https://trials-media.s3.amazonaws.com/orgs/instituto-nacional-de-cancerologia-de-mexico.jpeg)
Effectiveness and Quality of Life Analysis of Palonosetron Against Ondansetron Combined With Dexamethasone...
Breast NeoplasmAntineoplastic Agents2 moreNausea and vomiting are common complications on the chemotherapy (CT) and can affect the quality of life (QoL) of the patients. If not treated adequately it can produce other problems such as dehydration, weight loss, fatigue and even can induce the non-compliance of the treatment. In extreme cases it can put the patient ́s life at risk. There are various antiemetic treatments that vary both in cost and effectiveness. It ́s important to determine which are the strategies that are most effective and can improve the QoL of the patients. Methodology: The analysis will be done in patients who receive adjuvant and neoadjuvant chemotherapy and that have not received previously chemotherapy or radiotherapy, they will be stratified according to the emetogenic potential of the CT. They were given a diary of symptoms to register any discomfort suffered after receiving their treatment and also a quality of life questionnaire was applied previous to their first cycle and previous to their second cycle. The patients were divided in two groups receiving either A scheme (palonosetron) or B scheme (ondansetron) in combination with dexamethasone and fosaprepitant for prevention of early emesis and Dexamethasone to group A or Dexamethasone + metoclopramide to group B for prevention of delayed emesis. As well It was analyzed the three most prevalent single nucleotide polymorphisms (SNPs) on gene ABCB1 using PCR. The aim of this study is to evaluate the efficacy and quality of life provided by the 2 regimes noted above based on Mexican population so the results obtained can be applied widely in our country.