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Active clinical trials for "Neuralgia"

Results 671-680 of 1062

A Methodology Study Of Brain Imaging Of Pain-Killers In Post-Traumatic Neuropathic Pain Patients...

Pain

This study is a methodology study designed to discover whether a brain imaging technology is a better way of compare the relative sensitivities of fMRI and subjective psychometric assessments of pain to multiple doses of pregabalin and tramadol SR in a cross-over clinical study design.

Completed7 enrollment criteria

A Study of the Efficacy and Safety of Amitriptyline/Ketamine Topical Cream in Patients With Diabetic...

Diabetic Peripheral NeuropathyNeuralgia

This is a multicenter, randomized, placebo-controlled, parallel group study of EpiCept™ NP-1 Topical Cream (amitriptyline 4%/ketamine 2%) in approximately 200 patients with pain in the lower extremities due to diabetic nerve pain.

Completed2 enrollment criteria

P38 Mitogen-activated Protein (Map) Kinase Inhibitor (SB-681323)Study In Patients With Neuropathic...

PainNeuropathic

This will be a double-blind, placebo controlled cross-over study. After enrolment and initial assessments, subjects will receive oral SB681323 or matching placebo for 14 days. SB681323 will be administered twice daily at a total daily dose of 7.5mg. Sufficient numbers of patients will be recruited to obtain 40 evaluable patients

Completed44 enrollment criteria

Study of Pregabalin Therapy for Pain Relief in Subjects With Post-Herpetic Neuralgia

Post-Herpetic Neuralgia

The purpose of this study is to measure how rapidly pregabalin treatment can relieve pain in patients with post-herpetic neuralgia

Completed4 enrollment criteria

A Study to Validate a Pain Diary for Patient With Trigeminal Neuralgia

Trigeminal Neuralgia

The aim of the study is to establish the validity of a patient reported diary in TN . The following objectives have been identified: To generate evidence to support diary content validity by performing qualitative research studies with TN patients and Healthcare Professionals (HCPs). To provide further support to the diary, sensitivity to change, known groups validity (ability to differentiate between severity groups), and construct validity.

Active6 enrollment criteria

Impact of Adding TENS to Conventional Physical Therapy Exercise on Pain Relief Among Patients With...

Pudendal Neuralgia

Fifty two male participants, 30-50 years old, suffering from chronic pudendal neuralgia were randomly assigned either into experimental group (26 patients) received TENS plus the traditional physical therapy program( including range of motion exercise, stretching exercise of obturator internus muscle, clam shell exercise, relaxation exercise and underwater exercise) 3 sessions per week for 8 successive weeks, or control group (26 patients) received only the traditional physical therapy exercise for the same period of time. Intensity of pain by Verbal rating scale (VRS) as well as Serum cortisol level (SCL)and Etodolac level intake are measured pre and post treatment.

Completed10 enrollment criteria

ACD440 Gel in Peripheral Neuropathic Pain

Peripheral Neuropathic Pain

This is a double-blind, randomized, placebo-controlled crossover outpatient study in patients with peripheral neuropathic pain with allodynia or hyperalgesia to cold, heat, brush and/ or pinprick stimulation. Patients will in random order receive ACD440 Gel or placebo treatment twice daily for 7 days, topically applied to the painful area. This is followed by a 2-week washout period, then receive the alternate treatment.

Completed26 enrollment criteria

Regional Analgesia After Cesarean Section

Cesarean SectionPain3 more

All patients will be anaesthetized with spinal technique. Each patient will be treated with intravenous morphine - patient controlled analgesia (PCA). 2 of 3 groups of patients will receive ultrasound-guided transversus abdominis plane or quadratus lumborum block to treat postoperative pain. Postoperative pain will measured with visual-analogue scale (VAS). Total morphine consumption and time to the first demand will be noted. 1, 2, 6 months after surgery each patient will be called to assess neuropathic pain with Neuropathic Pain Symptom Inventory (NPSI).

Completed9 enrollment criteria

Transcranial Magnetic Stimulation for Facial Pain

Trigeminal Nerve InjuriesPost-herpetic Neuralgia2 more

Complex oro-facial pain is a poorly diagnosed and poorly treated cause of significant suffering and disability. This study will explore the ability of fMRI to identify patients with complex oro-facial pain who respond to transcranial magnetic stimulation therapy. Specific Aims: To establish baseline patterns of MRI in patients with chronic oro-facial pain without a definitive etiologic diagnosis. To estimate the rate of treatment success of transcranial stimulation of the primary motor cortex (M1) in these patients. To identify post-treatment MRI patterns that are associated with treatment success.

Completed40 enrollment criteria

Neuropathic Pain in Head and Neck Cancer

Head and Neck Cancer

The goal of this research study is to learn more about chronic pain associated with cancer treatment.

Active4 enrollment criteria
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