Phase II Study of Sunitinib Malate Following Hepatic Artery Embolization
Neuroendocrine TumorIslet Cell TumorThe purpose of this study is to decide if a medicine that slows growth of new blood vessels can be give after the embolization procedure to prevent or delay new growth of blood vessels to tumors.
Safety and Efficacy Study of In-111 Pentetreotide to Treat Neuroendocrine Tumors
Neuroendocrine TumorsThe purpose of this study is to determine if High-dose 111In-Pentetreotide known as NeuroendoMedix®, is an effective treatment for Neuroendocrine Tumors.
Bevacizumab in Combination With Temozolomide in Patients With Neuroendocrine Tumors
Neuroendocrine TumorsThe purpose of this study is to determine what effects (good and bad) bevacizumab and temozolomide have on patients with neuroendocrine tumors.
High Dose I-131 Metaiodobenzylguanidine(MIBG) for Metastatic Neuroendocrine Tumors
Neuroendocrine TumorsMetastases1 moreThe goal of this clinical research study is to learn if I-131 Metaiodobenzylguanidine (MIBG) can shrink or slow the growth of the tumor(s) in patients with metastatic neuroendocrine tumors. The safety of this treatment will also be studied.
Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC)...
Neuroendocrine TumorsMeningioma2 moreThis is a Phase 2 peptide receptor radionuclide therapy trial of 90Y-DOTATOC in patients with somatostatin receptor positive tumors.
A Pilot Study of Total-body PET Using FDA-approved Radiotracers Beyond 18F-FDG
Prostate CancerBreast Cancer1 moreThe purpose of this research study is to test new ways to improve the usefulness of the world's first total-body positron emission tomography (PET)/computed tomography (CT) scanner (EXPLORER) by collecting data from PET scans using one of three different imaging agents: 18F-PSMA; 18F-FES; or, 68Ga DOTATATE. These imaging agents are approved by the FDA to be used for patients diagnosed with prostate cancer (18F-PSMA), neuroendocrine tumor (68Ga DOTATATE), or breast cancer (18F-FES).
Multi-dimensional Fragmentomic Assay for Early Detection of Pancreatic Neuroendocrine Tumors
Pancreatic Neuroendocrine TumorThis prospective study aims to evaluate the sensitivity and specificity of an integrated model using fragmentomic profiles of plasma cell-free DNA for early detection of pancreatic neuroendocrine tumors.
Sapanisertib in Treating Patients With Metastatic or Refractory Pancreatic Neuroendocrine Tumor...
Pancreatic Neuroendocrine Tumor G1Pancreatic Neuroendocrine Tumor G21 moreThis phase II trial studies how well sapanisertib works in treating patients with pancreatic neuroendocrine tumor that has spread to other places in the body (metastatic), does not respond to treatment (refractory), or cannot be surgically removed. Drugs such as sapanisertib may stop the growth or shrink tumor cells by blocking some of the enzymes needed for cell growth.
68Ga-DOTA-TOC PET/CT in Imaging Participants With Neuroendocrine Tumors
MeningiomaMetastatic Well Differentiated Neuroendocrine Neoplasm4 moreThis trial studies how well gallium Ga 68-edotreotide (68Ga-DOTA-TOC) positron emission tomography (PET)/computer tomography (CT) works in imaging participants with neuroendocrine tumors. 68Ga-DOTA-TOC is used as a tracer chemical during PET/CT scans. Diagnostic procedures, such as 68Ga-DOTA-TOC PET/CT, may help find and diagnose neuroendocrine tumors.
Study of Everolimus (RAD001) in Combination With Lenalidomide
Solid Organ MalignanciesAdenoidcystic Carcinoma1 moreThe purpose of this study is to study the combination of two anticancer drugs, everolimus (RAD001) and lenalidomide in patients whose cancer is no longer responding to standard treatment or patients who are unable to tolerate the standard treatment for their cancer.