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Active clinical trials for "Carcinoma, Non-Small-Cell Lung"

Results 4061-4070 of 5094

A Study of Anlotinib in Combination With Docetaxel Versus Docetaxel Alone in Participants With Advanced...

Non-small Cell Lung Cancer

Evaluate the efficacy and safety of Anlotinib in combination with Docetaxel versus Docetaxel in patients with advanced non-small lung cancer after failure of first-line Chemotherapy .

Unknown status44 enrollment criteria

Study of Oral Nutritional Supplements During Concurrent Chemoradiotherapy for Local Advanced Non-small...

Local Advanced Non-small Cell Lung Cancer

This Phase II randomized study is to determine the efficacy of oral nutritional supplements(ONS) during concurrent chemoradiotherapy for local advanced non-small cell lung cancer, and discuss when to deliver ONS and which indicator should be the goal of ONS.

Unknown status9 enrollment criteria

A Study of Apatinib Plus EGFR-TKI as First Line Treatment in Patients With Non-squamous NSCLC Harboring...

NSCLC

The purpose of this study is to evaluate the efficacy and safety of apatinib plus EGFR-TKI as first line treatment in patients with non-squamous NSCLC harboring EGFR mutation.

Unknown status28 enrollment criteria

Safety, Tolerability and Pharmacokinetics of SH-1028 in Patients With Advanced NSCLC

Non-small Cell Lung Cancer

This is a Phase 1, open-label study of SH-1028 with dose escalation and dose expansion cohorts in locally advanced or metastatic non-small-cell lung cancer (NSCLC) patients who have progressed following prior therapy with an epidermal growth factor receptor(EGFR) tyrosine kinase inhibitor (TKI) agent.

Unknown status44 enrollment criteria

Phase I Study of the Combination of Anlotinib With Pemetrexed or Docetaxel

Non-squamous Non-small Cell Lung Cancer

The purpose of this clinical study is to evaluate the tolerability and toxicity of different dose of Anlotinib puls Pemetrexed/Docetaxel in Second-line Treatment of Advanced Gene Negative Non-squamous Non-small Cell Lung Cancer , to provide a reference of dosage for Phase II clinical trials

Unknown status34 enrollment criteria

Phase I Study of the Combination of Anlotinib With Gefitinib

Non-squamous Non-small Cell Lung Cancer

The purpose of this clinical study is to evaluate the tolerability and toxicity of different dose of Anlotinib puls Gefitinib in First-line Treatment of Advanced Gene Positive Non-squamous Non-small Cell Lung Cancer , to provide a reference of dosage for Phase II clinical trials

Unknown status44 enrollment criteria

Safety, Tolerability, Pharmacokinetics and Anti-tumour Activity of Alflutinib in Advanced Non Small...

NSCLC

Alflutinib Mesylate Tablets is a Epidermal Growth Factor Receptor (EGFR) mutation selective Tyrosine Kinase Inhibitor which can efficient suppress the EGFR T790M drug-resistant mutation tumor cell in Xenograft mouse model. This study aims at local advanced or metastatic non-small cell lung cancer patients with T790M drug-resistant mutation.

Unknown status25 enrollment criteria

High-dose Icotinib Treatment Beyond Progression in EGFR Mutant NSCLC

CarcinomaNon-Small-Cell Lung

The purpose of this study is to investigate whether high-dose icotinib treatment beyond disease progression is beneficial for NSCLC patients who have EGFR mutation and who have responded to EGFR TKI.

Unknown status16 enrollment criteria

Personalized DC Vaccine for Lung Cancer

CarcinomaNon-Small-Cell Lung

The study is aimed to the test the efficacy and safety of neoantigen-primed dendritic cell (DC) cell vaccine therapy for refractory non-small cell lung cancer.

Unknown status12 enrollment criteria

Endostar Plus EGFR-TKI(Epidermal Growth Factor Receptor-Tyrosine-Kinase Inhibitor) as a Treatment...

Advanced CancerLung Cancer1 more

EGFR Tyrosine-Kinase Inhibitor monotherapy is widely used in treatment of patients with EGFR mutation-positive Non-small cell lung cancer(NSCLC), In despite of the benefit of PFS (progression-free survival) , the OS ( overall survival) is limited extended. This study is aim to observe the safety and efficacy of the combination of an anti-angiogenic drug recombinant human-endostatin with EGFR TKI ,to find out a new strategy which may further extend the PFS and OS with a tolerated toxicity.

Unknown status2 enrollment criteria
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