
Morphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent Breathlessness...
Chronic Obstructive Pulmonary DiseaseInterstitial Lung DiseaseThe purpose of this study is to explore the role of low-dose immediate-release oral morphine as a novel adjunct pharmacotherapy to enable symptomatic adults with advanced chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD) to exercise at higher intensities for longer durations and maximize the psycho-physiological benefits of a supervised exercise training program. We hypothesize that, compared to placebo, exercise training with oral morphine will result in relatively greater improvements in exercise endurance time and intensity ratings of perceived breathlessness during constant-load cardiopulmonary cycle exercise testing (CPET) at 75% of peak power output (PPO).

High Flow Nasal Oxygen Versus Usual Care in COPD Pulmonary Rehabiliation
Chronic Obstructive Pulmonary DiseaseTo compare the effects of high flow nasal oxygen with usual care during an outpatient 6-week pulmonary rehabilitation program after hospitalization for COPD exacerbation.

Bufei Jianpi Granule for Delaying Pulmonary Function Decline in Early-Stage COPD
Chronic Obstructive Pulmonary DiseaseThis study aims to establish the treatment scheme of Bufei Jianpi granule for early-stage (GOLD stage 1 or 2) chronic obstructive pulmonary disease (COPD), delaying pulmonary function decline and forming high quality evidence.

Interactive 3D Visualization Technique Used in Pulmonary Rehabilitation Programme in COPD
Chronic Obstructive Pulmonary DiseaseA new education material with 3D technique was developed, by integrating 3D technology in an existing evidence-based pulmonary educational program, to enable an increased personalized education within a group setting. The investigators believe that this educational model will lead to increased adherence to treatment, and suggested lifestyle changes, which in turn improves patients' HRQL The purpose of this study was therefore to develop a pulmonary educational program in interactive 3D visualization technology and to evaluate differences between education with 3D technique or conventional technique in patient with COPD. Furthermore the LCQ will be translated and culturally adapted into Swedish and tested for validity and reliability.

Anti-viral Effects of Azithromycin in Patients With Asthma and COPD
AsthmaCOPD7 moreThe purpose of this study is to investigate the anti-viral effects of low-dose AZM treatment in patients with asthma and COPD with an exacerbation history. The investigators expect that long-term treatment with low dose AZM modulates the immune response to viral infections, with an increased interferon release, in patients with asthma and COPD with an exacerbation history. In addition, the investigators expect a decrease in inflammatory cells and mediators, and changes in bacteria, measured in samples from the lungs. Half of the participants will receive azithromycin on top of their regular asthma/COPD treatment, while the other half will receive placebo on top of their regular asthma/COPD treatment.

Yiqi Huoxue Huatan Granule for Reducing Mortality in COPD With Chronic Respiratory Failure
Chronic Obstructive Pulmonary DiseaseChronic Respiratory FailureThis study aims to establish the treatment scheme of Yiqi Huoxue Huatan granule for chronic obstructive pulmonary disease (COPD) with chronic respiratory failure (CRF), reducing mortality, improving quality of life and forming high quality evidence.

A Study to Evaluate the Effect of Yoga Exercises and Meditation on Lung Function and Quality of...
COPDObstructive Pulmonary DiseaseThe Investigator would like to study the effect of yoga exercises and meditation on lung volume, respiratory impedance, 6-minute walk distance and quality of life in COPD patients.

Efficacy and Safety of Tulobuterol Patch Combined With Tiotropium Bromide for Relieving Dyspnea...
Chronic Obstructive Pulmonary DiseasePhrase: IV Indication: dyspnea symptom of chronic obstructive pulmonary disease (COPD) Objective: to evaluate efficacy and safety of tulobuterol patch combined with Tiotropium bromide for relieving dyspnea symptom of COPD Design: a multi-centre randomized parallel blank control study Case number: test group 80, control group 80, totally 160 Site number:7 Study period: 2010.9 - 2011.8

Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome...
Chronic Obstructive Pulmonary DiseaseObstructive Sleep Apnea1 moreThe purpose of this study is to determine if Bipap should assume a standard-of-care role in the management of overlap syndrome.

Inhaled Iloprost for Disproportionate Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease...
Chronic Obstructive Pulmonary DiseasePulmonary hypertension is frequently present in COPD and it is generally limited to a mild increase in mean pulmonary artery pressure. However some COPD patients are characterized by higher levels of mPAP at rest, fulfilling the definition of moderate or severe PH disproportionate PH . In these patients the elevated pulmonary pressures adversely affect the prognosis.At the present time the evidence for the the use of specific pulmonary vasodilators in the management of these patients are scarce and cannot be recommended.the aim of this study is to evaluate the medium term efficacy and safety of the inhaled prostacyclin stable analog, iloprost in patients with COPD and moderate to severe pulmonary hypertension