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Active clinical trials for "Rosacea"

Results 61-70 of 196

Phase 3 Papulopustular Rosacea Study

Papulopustular Rosacea

The purpose of this study is to demonstrate that CD5024 1% cream is more effective than its vehicle when applied once daily, at bed time, during a 12 week period in subjects with Papulopustular Rosacea (PPR) and continues to be safe up to 12 months.

Completed4 enrollment criteria

Safety and Efficacy of Azelaic Acid Foam, 15 % in Papulopustular Rosacea

Papulopustular Rosacea

The purpose of this study is to assess the safety and efficacy of azelaic acid (AzA) foam, 15% topically applied twice daily for 12 weeks in subjects with papulopustular rosacea compared to its vehicle.

Completed14 enrollment criteria

A Study to Evaluate the Safety, Tolerability, and Effects of Anatabloc® Crème in Rosacea

Rosacea

This is a multi-site, four-visit, eight-week, double-blind, randomized, vehicle-controlled, parallel-group study followed by an eight-week open-label extension to evaluate the safety, tolerability, and potential effects of Anatabloc Facial Cream. The secondary aim is to evaluate if Anatabloc Facial Cream improves the appearance of the skin in subjects with mild to moderate rosacea.

Completed7 enrollment criteria

Randomized, Double-blind, Multiple-site, Placebo-controlled, Parallel-design Study in Patients With...

Rosacea

A Randomized, Double-Blind, Multiple-Site, Placebo-Controlled, Parallel-Design Study to Evaluate the Safety and Therapeutic Equivalence of Brimonidine Topical Gel, 0.33% (Watson Laboratories, Inc., USA) to Reference Product Mirvaso® (brimonidine) topical gel, 0.33% (Galderma Laboratories, L.P., USA) in Patients with Moderate to Severe Facial Erythema Associated with Rosacea

Completed33 enrollment criteria

Patient-Reported Outcome Of Facial Erythema (PROOF)

RosaceaErythema

The purpose of the study is to evaluate the patient-reported outcomes (feedbacks of patients)of a new drug for the treatment of erythema of rosacea (central facial redness). The feedback of patients receiving the active drug will be compared to the feedback of patients receiving the placebo.

Completed8 enrollment criteria

An Analysis of the Effect of Topical Cromolyn Sodium on Rosacea-associated Erythema

Papulopustular Rosacea

This study is designed to investigate whether topical application of a cromolyn sodium solution is able to decrease the facial redness seen in patients with papulopustular rosacea. Previous work in the lab of Dr. Di Nardo on mice has suggested that cromolyn may be able to have this effect. The study will enroll a total of 10 patients. 5 will randomly be assigned to receive the cromolyn sodium solution, and the other 5 will be randomly assigned to receive the placebo solution. All participants will be instructed to apply their assigned solution twice daily to their face. Patients will return to the clinic 3, 6, and 8 weeks after the distribution of the solutions to measure the efficacy of their assigned solution.

Completed18 enrollment criteria

Combination Therapy for the Treatment of Rosacea

Erythematotelangiectatic Rosacea

The purpose of this study is to determine the efficacy of calcium dobesilate in combination with pulsed dye laser for the treatment of rosacea.

Completed18 enrollment criteria

A Multicenter Trial of a Topical Medication for Papulopustular Rosacea Applied Twice Daily Versus...

Papulopustular Rosacea

To assess the efficacy and tolerability of azelaic acid 15% gel applied once daily versus twice daily in the treatment of patients with papulopustular rosacea.

Completed6 enrollment criteria

Treatment of Patients With Blepharitis and Facial Rosacea

BlepharitisMeibomianitis1 more

To determine the safety and efficacy of sub-antimicrobial dose COL-101 in the treatment of patients who have both blepharitis and facial rosacea

Completed8 enrollment criteria

Safety, Efficacy and Pharmacokinetics of Rifaximin in Patients With Moderate-to-severe Papulopustular...

Papulopustular Rosacea

Rosacea is a common chronic inflammatory relapsing-remitting skin condition almost exclusively affecting the central area of the face and the eyes. Preliminary evidence suggests that treatment with rifaximin, a poorly absorbed oral antibiotic drug may be beneficial in patients with rosacea, particularly in those with papulopustular phenotype and positivity to Lactulose Breath Test (L-BT). The objective of this study is twofold: To explore the safety and efficacy of 2 doses of oral Rifaximin versus placebo in adults with moderate-to-severe papulopustular rosacea. To assess the pharmacokinetics (PK) of these two dose regimens in a sub-group of patients.

Completed33 enrollment criteria
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